FR2197003B1 - - Google Patents

Info

Publication number
FR2197003B1
FR2197003B1 FR7330353A FR7330353A FR2197003B1 FR 2197003 B1 FR2197003 B1 FR 2197003B1 FR 7330353 A FR7330353 A FR 7330353A FR 7330353 A FR7330353 A FR 7330353A FR 2197003 B1 FR2197003 B1 FR 2197003B1
Authority
FR
France
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR7330353A
Other languages
French (fr)
Other versions
FR2197003A1 (US08118993-20120221-C00002.png
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of FR2197003A1 publication Critical patent/FR2197003A1/fr
Application granted granted Critical
Publication of FR2197003B1 publication Critical patent/FR2197003B1/fr
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/141,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/161,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/181,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/141,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/161,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/181,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24Oxygen atoms
    • C07D243/28Preparation including building-up the benzodiazepine skeleton from compounds containing no hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D243/00Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/141,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines
    • C07D243/161,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals
    • C07D243/181,4-Benzodiazepines; Hydrogenated 1,4-benzodiazepines substituted in position 5 by aryl radicals substituted in position 2 by nitrogen, oxygen or sulfur atoms
    • C07D243/24Oxygen atoms
    • C07D243/30Preparation including building-up the benzodiazepine skeleton from compounds already containing hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
FR7330353A 1972-08-21 1973-08-21 Expired FR2197003B1 (US08118993-20120221-C00002.png)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US28221772A 1972-08-21 1972-08-21
US35981473A 1973-05-14 1973-05-14

Publications (2)

Publication Number Publication Date
FR2197003A1 FR2197003A1 (US08118993-20120221-C00002.png) 1974-03-22
FR2197003B1 true FR2197003B1 (US08118993-20120221-C00002.png) 1978-01-13

Family

ID=26961312

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7330353A Expired FR2197003B1 (US08118993-20120221-C00002.png) 1972-08-21 1973-08-21

Country Status (24)

Country Link
JP (1) JPS5911589B2 (US08118993-20120221-C00002.png)
AR (1) AR198108A1 (US08118993-20120221-C00002.png)
AT (1) AT341527B (US08118993-20120221-C00002.png)
AU (1) AU472777B2 (US08118993-20120221-C00002.png)
CA (1) CA1012535A (US08118993-20120221-C00002.png)
CH (1) CH578544A5 (US08118993-20120221-C00002.png)
DD (1) DD107040A5 (US08118993-20120221-C00002.png)
DE (1) DE2340159A1 (US08118993-20120221-C00002.png)
DK (1) DK155326C (US08118993-20120221-C00002.png)
ES (1) ES418014A1 (US08118993-20120221-C00002.png)
FI (1) FI57939C (US08118993-20120221-C00002.png)
FR (1) FR2197003B1 (US08118993-20120221-C00002.png)
GB (1) GB1392681A (US08118993-20120221-C00002.png)
HU (1) HU170153B (US08118993-20120221-C00002.png)
IE (1) IE38091B1 (US08118993-20120221-C00002.png)
IL (1) IL42947A (US08118993-20120221-C00002.png)
LU (1) LU68269A1 (US08118993-20120221-C00002.png)
NL (1) NL179582C (US08118993-20120221-C00002.png)
NO (1) NO139481C (US08118993-20120221-C00002.png)
PH (1) PH13640A (US08118993-20120221-C00002.png)
PL (1) PL99162B1 (US08118993-20120221-C00002.png)
SE (1) SE408302B (US08118993-20120221-C00002.png)
SU (1) SU550980A3 (US08118993-20120221-C00002.png)
YU (1) YU219873A (US08118993-20120221-C00002.png)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5334792A (en) * 1976-09-13 1978-03-31 Scherico Ltd Production of 1*44 benzodiazepines and 1*44 benzodiazepinee22ones
CN113149915B (zh) * 2021-03-01 2024-03-15 中国科学院成都有机化学有限公司 一种合成氯硝西泮化合物的方法
CN116023342B (zh) * 2021-10-26 2024-06-25 江苏昱林生物科技有限公司 一种高纯度氯硝西泮的制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1136709B (de) * 1959-12-10 1962-09-20 Hoffmann La Roche Verfahren zur Herstellung von 2-Oxo-1, 2-dihydro-1, 4-benzodiazepinen
CH537393A (de) * 1969-10-16 1973-05-31 Hoffmann La Roche Verfahren zur Herstellung von 1,4-Benzodiazepin-derivaten
BE785962A (fr) * 1971-07-08 1973-01-08 Hoffmann La Roche Procede pour la preparation de derives de benzodiazepine

Also Published As

Publication number Publication date
GB1392681A (en) 1975-04-30
FI57939B (fi) 1980-07-31
SE408302B (sv) 1979-06-05
YU219873A (en) 1982-06-30
DK155326C (da) 1989-08-14
AR198108A1 (es) 1974-05-31
DE2340159C2 (US08118993-20120221-C00002.png) 1989-01-19
AU472777B2 (en) 1976-06-03
JPS5911589B2 (ja) 1984-03-16
LU68269A1 (US08118993-20120221-C00002.png) 1975-05-21
FR2197003A1 (US08118993-20120221-C00002.png) 1974-03-22
NL7311507A (US08118993-20120221-C00002.png) 1974-02-25
ATA720773A (de) 1977-06-15
IE38091B1 (en) 1977-12-21
FI57939C (fi) 1980-11-10
PH13640A (en) 1980-08-18
NL179582C (nl) 1986-10-01
IL42947A0 (en) 1973-11-28
NO139481C (no) 1979-03-21
CA1012535A (en) 1977-06-21
HU170153B (US08118993-20120221-C00002.png) 1977-04-28
IL42947A (en) 1977-01-31
AU5918073A (en) 1975-02-13
SU550980A3 (ru) 1977-03-15
DK155326B (da) 1989-03-28
ES418014A1 (es) 1976-03-16
DE2340159A1 (de) 1974-03-07
IE38091L (en) 1974-02-21
AT341527B (de) 1978-02-10
NO139481B (no) 1978-12-11
JPS4956992A (US08118993-20120221-C00002.png) 1974-06-03
PL99162B1 (pl) 1978-06-30
DD107040A5 (US08118993-20120221-C00002.png) 1974-07-12
CH578544A5 (US08118993-20120221-C00002.png) 1976-08-13
NL179582B (nl) 1986-05-01

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Legal Events

Date Code Title Description
ST Notification of lapse