FR2163358A1 - Phenylalkanolamine derivs - with effects on the smooth musculature - Google Patents

Phenylalkanolamine derivs - with effects on the smooth musculature

Info

Publication number
FR2163358A1
FR2163358A1 FR7145106A FR7145106A FR2163358A1 FR 2163358 A1 FR2163358 A1 FR 2163358A1 FR 7145106 A FR7145106 A FR 7145106A FR 7145106 A FR7145106 A FR 7145106A FR 2163358 A1 FR2163358 A1 FR 2163358A1
Authority
FR
France
Prior art keywords
alkyl
nr3r4
benzyl
derivs
phenylalkanolamine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7145106A
Other languages
English (en)
French (fr)
Other versions
FR2163358B1 (enrdf_load_stackoverflow
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Synthelabo SA
Original Assignee
Synthelabo SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synthelabo SA filed Critical Synthelabo SA
Priority to FR7145106A priority Critical patent/FR2163358A1/fr
Priority to DE19722261506 priority patent/DE2261506A1/de
Priority to JP47126011A priority patent/JPS4867234A/ja
Publication of FR2163358A1 publication Critical patent/FR2163358A1/fr
Application granted granted Critical
Publication of FR2163358B1 publication Critical patent/FR2163358B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/06—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom
    • C07D213/16—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom containing only hydrogen and carbon atoms in addition to the ring nitrogen atom containing only one pyridine ring
    • C07D213/20—Quaternary compounds thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/02—Preparation by ring-closure or hydrogenation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/10—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms
    • C07D211/14—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms with hydrocarbon or substituted hydrocarbon radicals attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D211/62—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4
    • C07D211/64—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4 having an aryl radical as the second substituent in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/092—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings with aromatic radicals attached to the chain

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyridine Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
FR7145106A 1971-12-15 1971-12-15 Phenylalkanolamine derivs - with effects on the smooth musculature Granted FR2163358A1 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
FR7145106A FR2163358A1 (en) 1971-12-15 1971-12-15 Phenylalkanolamine derivs - with effects on the smooth musculature
DE19722261506 DE2261506A1 (de) 1971-12-15 1972-12-15 Basische derivate von phenyl-1 alkanolen, ihre herstellung und diese enthaltende medikamente
JP47126011A JPS4867234A (enrdf_load_stackoverflow) 1971-12-15 1972-12-15

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7145106A FR2163358A1 (en) 1971-12-15 1971-12-15 Phenylalkanolamine derivs - with effects on the smooth musculature

Publications (2)

Publication Number Publication Date
FR2163358A1 true FR2163358A1 (en) 1973-07-27
FR2163358B1 FR2163358B1 (enrdf_load_stackoverflow) 1975-03-14

Family

ID=9087537

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7145106A Granted FR2163358A1 (en) 1971-12-15 1971-12-15 Phenylalkanolamine derivs - with effects on the smooth musculature

Country Status (3)

Country Link
JP (1) JPS4867234A (enrdf_load_stackoverflow)
DE (1) DE2261506A1 (enrdf_load_stackoverflow)
FR (1) FR2163358A1 (enrdf_load_stackoverflow)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2534580A1 (fr) * 1982-10-13 1984-04-20 Synthelabo Derives de phenyl-1 piperidino-2 propanol, leur preparation, et medicaments qui les contiennent
FR2541275A1 (fr) * 1982-12-02 1984-08-24 Nippon Chemiphar Co Nouveaux derives de la piperazine et leurs sels, leur procede de preparation et leur application en therapeutique
EP0288563A4 (en) * 1986-09-30 1990-09-26 Eisai Co., Ltd. Cyclic amine derivatives

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5830306B2 (ja) * 1972-07-18 1983-06-28 ヒサミツセイヤク カブシキカイシヤ アミノアルコ−ルユウドウタイ ノ セイゾウホウホウ
US4022776A (en) * 1974-01-31 1977-05-10 Otsuka Pharmaceutical Company Limited 5-[1-Hydroxy-2-(substituted-amino)]ethyl-8-hydroxycarbostyril derivatives
US4022784A (en) * 1974-01-31 1977-05-10 Otsuka Pharmaceutical Company Limited 5-[1-Hydroxy-2-(substituted-amino)]alkyl-8-substituted-carbostyril and -3,4-dihydrocarbostyril derivatives
GB1508208A (en) 1975-12-05 1978-04-19 Ici Ltd Amide derivatives
JPS6034951B2 (ja) * 1979-09-13 1985-08-12 東洋フアルマ−株式会社 １−（４−ヒドロキシフエニル）−２−（４−ベンジルピペリジノ）プロパン−１−オ−ルの製造方法
JPS5677258A (en) * 1979-11-28 1981-06-25 Grelan Pharmaceut Co Ltd Preparation of erythro 2- 4-benzylpiperidino -1- 4-hydroxyphenyl propanol
JPS5679667A (en) * 1979-12-04 1981-06-30 Grelan Pharmaceut Co Ltd Preparation of erythro 2- 4-benzylpiperidino -1- 4- hydroxyphenyl propanol
JPS5679666A (en) * 1979-12-04 1981-06-30 Grelan Pharmaceut Co Ltd Erythro 1- 4-benzyloxyphenyl -2- 4-benzylpiperidino propanol and its preparation
JPS591467A (ja) * 1983-02-09 1984-01-06 Grelan Pharmaceut Co Ltd ピペリジノアルカノン類とその塩およびそれらの製造法
JPS601165A (ja) * 1984-05-22 1985-01-07 Grelan Pharmaceut Co Ltd ピペリジノアルカノ−ル類
WO1987000433A1 (en) * 1985-07-24 1987-01-29 Grelan Pharmaceutical Co., Ltd. Circulation improving agent
JP2573195B2 (ja) * 1986-09-30 1997-01-22 エーザイ株式会社 環状アミン誘導体

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2534580A1 (fr) * 1982-10-13 1984-04-20 Synthelabo Derives de phenyl-1 piperidino-2 propanol, leur preparation, et medicaments qui les contiennent
EP0109317A3 (en) * 1982-10-13 1984-08-08 Synthelabo Phenyl-1-piperidino-2-propanol derivatives, their preparation and medicaments containing them
FR2541275A1 (fr) * 1982-12-02 1984-08-24 Nippon Chemiphar Co Nouveaux derives de la piperazine et leurs sels, leur procede de preparation et leur application en therapeutique
EP0288563A4 (en) * 1986-09-30 1990-09-26 Eisai Co., Ltd. Cyclic amine derivatives

Also Published As

Publication number Publication date
JPS4867234A (enrdf_load_stackoverflow) 1973-09-13
FR2163358B1 (enrdf_load_stackoverflow) 1975-03-14
DE2261506A1 (de) 1973-06-28

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Legal Events

Date Code Title Description
ST Notification of lapse