FR2150240A2 - 5-cinnamoyl-4,7-dimethoxy-6-tertiary amino alkyl - -benzofurans - vasodilators,hypotensives,diuretics,spasmolytics,analg - Google Patents

5-cinnamoyl-4,7-dimethoxy-6-tertiary amino alkyl - -benzofurans - vasodilators,hypotensives,diuretics,spasmolytics,analg

Info

Publication number
FR2150240A2
FR2150240A2 FR7130853A FR7130853A FR2150240A2 FR 2150240 A2 FR2150240 A2 FR 2150240A2 FR 7130853 A FR7130853 A FR 7130853A FR 7130853 A FR7130853 A FR 7130853A FR 2150240 A2 FR2150240 A2 FR 2150240A2
Authority
FR
France
Prior art keywords
hypotensives
spasmolytics
analg
benzofurans
cinnamoyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7130853A
Other languages
French (fr)
Other versions
FR2150240B2 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Synthelabo SA
Original Assignee
Delalande SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to BE787838D priority Critical patent/BE787838R/en
Application filed by Delalande SA filed Critical Delalande SA
Priority to FR7130853A priority patent/FR2150240A2/en
Priority to DE19722238115 priority patent/DE2238115C3/en
Priority to IL40184A priority patent/IL40184A/en
Priority to GB3898372A priority patent/GB1399662A/en
Priority to ZA725804A priority patent/ZA725804B/en
Priority to LU65937A priority patent/LU65937A1/xx
Priority to CH1248972A priority patent/CH544084A/en
Priority to US283055A priority patent/US3862176A/en
Priority to SE7210992A priority patent/SE403376B/en
Priority to NL7211577A priority patent/NL7211577A/xx
Priority to AU45912/72A priority patent/AU466133B2/en
Priority to ES406084A priority patent/ES406084A2/en
Priority to CA150,310A priority patent/CA966125A/en
Priority to SU1827679A priority patent/SU435611A3/en
Priority to YU02168/72A priority patent/YU216872A/en
Priority to AT734172A priority patent/AT326116B/en
Priority to JP47084680A priority patent/JPS5220995B2/ja
Priority to IT69736/72A priority patent/IT1052683B/en
Publication of FR2150240A2 publication Critical patent/FR2150240A2/en
Application granted granted Critical
Publication of FR2150240B2 publication Critical patent/FR2150240B2/fr
Granted legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/86Benzo [b] furans; Hydrogenated benzo [b] furans with an oxygen atom directly attached in position 7

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Novel title cpds of formula: (where -NR1R2 = dimethylamino, diethylamino, diisopropylamino or a pyrrolidino, piperidino, morpholino or perhydroazepino ring, n = 2 or 3, R3, R4, R5 = H, 1-4C alkoxy, halo or hydroxy or two of the gps. together form a methylenedioxy gp. the other being H), and their acid addn salts are prepd. by condensing a khellinone deriv with a benzaldehyde under alkaline conditions.
FR7130853A 1971-08-25 1971-08-25 5-cinnamoyl-4,7-dimethoxy-6-tertiary amino alkyl - -benzofurans - vasodilators,hypotensives,diuretics,spasmolytics,analg Granted FR2150240A2 (en)

Priority Applications (19)

Application Number Priority Date Filing Date Title
BE787838D BE787838R (en) 1971-08-25 NEW DERIVATIVES OF CINNAMOYL-5 BENZOFURANNE, THEIR PROCESS FOR PREPARATION AND THEIR USE IN THERAPEUTICS
FR7130853A FR2150240A2 (en) 1971-08-25 1971-08-25 5-cinnamoyl-4,7-dimethoxy-6-tertiary amino alkyl - -benzofurans - vasodilators,hypotensives,diuretics,spasmolytics,analg
DE19722238115 DE2238115C3 (en) 1971-08-25 1972-08-02 5-Cinnamoyl-benzofuran derivatives, processes for their preparation and pharmaceuticals containing these compounds
IL40184A IL40184A (en) 1971-08-25 1972-08-22 5-cinnamoyl-benzofurans,their preparation and pharmaceutical compositions containing them
GB3898372A GB1399662A (en) 1971-08-25 1972-08-22 Derivarives of 5-cinnamoyl benzofuran and process for the preparation thereof
LU65937A LU65937A1 (en) 1971-08-25 1972-08-23
CH1248972A CH544084A (en) 1971-08-25 1972-08-23 Process for the preparation of cinnamoyl-5-benzofuran derivatives
US283055A US3862176A (en) 1971-08-25 1972-08-23 Derivatives of 5-cinnamoyl benzofuran
ZA725804A ZA725804B (en) 1971-08-25 1972-08-23 Novel derivatives of 5-cinnamoyl benzofuran,process for their preparation and their therapeutic use
AU45912/72A AU466133B2 (en) 1971-08-25 1972-08-24 Derivatives of 5-cinnamoyl-benzofuran
SE7210992A SE403376B (en) 1971-08-25 1972-08-24 METHOD OF MAKING DERIVATIVES OF 5-CINNAMOYL BENZOFURAN
ES406084A ES406084A2 (en) 1971-08-25 1972-08-24 Derivatives of 5-cinnamoyl benzofuran
CA150,310A CA966125A (en) 1971-08-25 1972-08-24 Derives du cinnamoyl-5-benzofuranne, leur procede de preparation et leur utilisation en therapeutique
SU1827679A SU435611A3 (en) 1971-08-25 1972-08-24 METHOD FOR PRODUCING 5-CINNAMOILBENZENOFURANE DERIVATIVES
NL7211577A NL7211577A (en) 1971-08-25 1972-08-24
YU02168/72A YU216872A (en) 1971-08-25 1972-08-25 Process for preparing cinnamoyl-5-benzofuran derivatives
AT734172A AT326116B (en) 1971-08-25 1972-08-25 PROCESS FOR THE PRODUCTION OF NEW 5-CINNAMOYL-BENZOFURAN DERIVATIVES AND THEIR SALT
JP47084680A JPS5220995B2 (en) 1971-08-25 1972-08-25
IT69736/72A IT1052683B (en) 1971-08-25 1972-08-25 ORIGINAL DERIVATIVES OF CINNAMOIL 5 BENZOFURAN AND THEIR PREPARATION PROCEDURE AND THEIR USE IN THERAPY

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7130853A FR2150240A2 (en) 1971-08-25 1971-08-25 5-cinnamoyl-4,7-dimethoxy-6-tertiary amino alkyl - -benzofurans - vasodilators,hypotensives,diuretics,spasmolytics,analg

Publications (2)

Publication Number Publication Date
FR2150240A2 true FR2150240A2 (en) 1973-04-06
FR2150240B2 FR2150240B2 (en) 1974-10-18

Family

ID=9082210

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7130853A Granted FR2150240A2 (en) 1971-08-25 1971-08-25 5-cinnamoyl-4,7-dimethoxy-6-tertiary amino alkyl - -benzofurans - vasodilators,hypotensives,diuretics,spasmolytics,analg

Country Status (3)

Country Link
AT (1) AT326116B (en)
FR (1) FR2150240A2 (en)
ZA (1) ZA725804B (en)

Also Published As

Publication number Publication date
ZA725804B (en) 1973-05-30
ATA734172A (en) 1975-02-15
AT326116B (en) 1975-11-25
FR2150240B2 (en) 1974-10-18

Similar Documents

Publication Publication Date Title
ES405011A1 (en) Hydroxyl-terminated polylactones
GB1344976A (en) Aminoalkanol compounds and methods for their production
GB1399662A (en) Derivarives of 5-cinnamoyl benzofuran and process for the preparation thereof
GB1359951A (en) Ny-tertiary-4,-aminomethyl-dibenzo-b,e-11-oxepine-2,-spiro- 1,3,-dioxolanes their process of preparation and their thera peutic application
BE790119A (en) PROCESS FOR THE PREPARATION OF SECONDARY OR TERTIARY ALIPHATIC AND CYCLOALIPHATIC AMINES.
FR2150240A2 (en) 5-cinnamoyl-4,7-dimethoxy-6-tertiary amino alkyl - -benzofurans - vasodilators,hypotensives,diuretics,spasmolytics,analg
FR2192807A2 (en) 5-cinnamoyl-4,7-dimethoxy-6-tertiary amino alkyl - -benzofurans - vasodilators,hypotensives,diuretics,spasmolytics,analg
CH557706A (en) PROCESS FOR MANUFACTURING A CORE.
FR2154082A5 (en) Antiarrhythmic piperazine derivs prepn - from benzhydrylpiperazine cinnamaldehyde by leuckart reactn
JPS5795946A (en) Manufacture of 1-amino-3-aryloxy-2-propanol and 1-amino-2-aryl-2-ethanol
ES394969A1 (en) 5-(2-amino-alkoxy-phenoxy-methyl)-3-alkyl-isoxazoles - useful as hypotensives and sedatives
FR2163322A1 (en) Tert aminomethyl pentenyl dioxolanes - vasodilators hypotensives spasmolytics diuretics and analgesics
FR2142648A1 (en) 4,7-dimethoxy benzofurant derivs - diuretics vasodilators hypotensives spasmolytics bradycardiants and antiulcer agents
SU467211A1 (en) Ventilator Packing
GB1364615A (en) Preparation of n -diethylaminoethyl - 2 - methoxy- 5 - methyl sulphonylbenzamide
GB1377244A (en) Production of formaldehyde
FR2175634A1 (en) Carboxymethoxybenzofurans derivs - analgesic antiinflammatory hypotensive activity etc
FR2100973A1 (en) 5-Aminopyrazoles - with analgesic, antiinflammatory and muscle relaxant activity
FR2150594A1 (en) Omega-amino-1,2-diphenyl-1-alkanones - with analgesic antiinflammatory anti-ulcer,bronchodilator,spasmolytic and hypotensive
FR2139269A5 (en) Antiarrhythmic piperazine derivs prepn - from benzhydrylpiperazine cinnamaldehyde by leuckart reactn
ES394968A1 (en) 5-(2-amino-alkoxy-phenoxy-methyl)-3-alkyl-isoxazoles - useful as hypotensives and sedatives
GB1337377A (en) Process for the preparation of ethyl 8-hydroxy-1,3-dioxolo
FR2178815A1 (en) Furo-benzoxazole derivs - analgesics, vasodilators, diuretics, etc
BE782977A (en) Antiarrhythmic piperazine derivs prepn - from benzhydrylpiperazine cinnamaldehyde by leuckart reactn
GB1389834A (en) Treatment of textile materials