FR2149275A1 - 4-(3-dialkylaminopropylamino)-1,3-dimethyl-1h-pyrazolo - (3,4-b) quinolines - with hypocholesterolaemic and hypolipaemic activ - Google Patents

4-(3-dialkylaminopropylamino)-1,3-dimethyl-1h-pyrazolo - (3,4-b) quinolines - with hypocholesterolaemic and hypolipaemic activ

Info

Publication number
FR2149275A1
FR2149275A1 FR7129821A FR7129821A FR2149275A1 FR 2149275 A1 FR2149275 A1 FR 2149275A1 FR 7129821 A FR7129821 A FR 7129821A FR 7129821 A FR7129821 A FR 7129821A FR 2149275 A1 FR2149275 A1 FR 2149275A1
Authority
FR
France
Prior art keywords
hypocholesterolaemic
hypolipaemic
dialkylaminopropylamino
activ
quinolines
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7129821A
Other languages
French (fr)
Other versions
FR2149275B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Co
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Priority to FR7129821A priority Critical patent/FR2149275A1/en
Publication of FR2149275A1 publication Critical patent/FR2149275A1/en
Application granted granted Critical
Publication of FR2149275B1 publication Critical patent/FR2149275B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/38—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/04—1,3-Oxazines; Hydrogenated 1,3-oxazines
    • C07D265/12—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems
    • C07D265/14—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D265/20—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with hetero atoms directly attached in position 4
    • C07D265/22—Oxygen atoms

Abstract

Cpds. of formula (I): (where R1 and R2 are lower alkyl, and pref. R1=R2=Me, Et, n-Pr or i-Pr, or R1 = Me and r2 = Et) have hypocholesterolaemic and hypolipaemic activity. They are pref. by reaction of a cpd. (II): with H2NCH2CH2CH2NR1R2, pref. in a solvent at 100-200 degrees C.
FR7129821A 1971-08-16 1971-08-16 4-(3-dialkylaminopropylamino)-1,3-dimethyl-1h-pyrazolo - (3,4-b) quinolines - with hypocholesterolaemic and hypolipaemic activ Granted FR2149275A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR7129821A FR2149275A1 (en) 1971-08-16 1971-08-16 4-(3-dialkylaminopropylamino)-1,3-dimethyl-1h-pyrazolo - (3,4-b) quinolines - with hypocholesterolaemic and hypolipaemic activ

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7129821A FR2149275A1 (en) 1971-08-16 1971-08-16 4-(3-dialkylaminopropylamino)-1,3-dimethyl-1h-pyrazolo - (3,4-b) quinolines - with hypocholesterolaemic and hypolipaemic activ

Publications (2)

Publication Number Publication Date
FR2149275A1 true FR2149275A1 (en) 1973-03-30
FR2149275B1 FR2149275B1 (en) 1974-09-06

Family

ID=9081902

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7129821A Granted FR2149275A1 (en) 1971-08-16 1971-08-16 4-(3-dialkylaminopropylamino)-1,3-dimethyl-1h-pyrazolo - (3,4-b) quinolines - with hypocholesterolaemic and hypolipaemic activ

Country Status (1)

Country Link
FR (1) FR2149275A1 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0813533A1 (en) * 1995-03-10 1997-12-29 Sanofi Winthrop, Inc. SUBSTITUTED N-CYCLOALKYLMETHYL-1H-PYRAZOLO 3,4-b]QUINOLIN-4 AMINES AND COMPOSITIONS AND METHODS OF USE THEREOF

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0813533A1 (en) * 1995-03-10 1997-12-29 Sanofi Winthrop, Inc. SUBSTITUTED N-CYCLOALKYLMETHYL-1H-PYRAZOLO 3,4-b]QUINOLIN-4 AMINES AND COMPOSITIONS AND METHODS OF USE THEREOF
EP0813533A4 (en) * 1995-03-10 2000-01-19 Sanofi Winthrop Inc SUBSTITUTED N-CYCLOALKYLMETHYL-1H-PYRAZOLO 3,4-b]QUINOLIN-4 AMINES AND COMPOSITIONS AND METHODS OF USE THEREOF

Also Published As

Publication number Publication date
FR2149275B1 (en) 1974-09-06

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