FR2126306A1 - Ajmalicine nicotinate - antihypertensive - Google Patents

Ajmalicine nicotinate - antihypertensive

Info

Publication number
FR2126306A1
FR2126306A1 FR7205969A FR7205969A FR2126306A1 FR 2126306 A1 FR2126306 A1 FR 2126306A1 FR 7205969 A FR7205969 A FR 7205969A FR 7205969 A FR7205969 A FR 7205969A FR 2126306 A1 FR2126306 A1 FR 2126306A1
Authority
FR
France
Prior art keywords
ajmalicine
nicotinate
antihypertensive
prepd
reaction
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7205969A
Other languages
French (fr)
Other versions
FR2126306B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Gruppo Lepetit SpA
Original Assignee
Gruppo Lepetit SpA
Lepetit SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gruppo Lepetit SpA, Lepetit SpA filed Critical Gruppo Lepetit SpA
Publication of FR2126306A1 publication Critical patent/FR2126306A1/en
Application granted granted Critical
Publication of FR2126306B1 publication Critical patent/FR2126306B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79—Acids; Esters
    • C07D213/80—Acids; Esters in position 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Title cpd. is of formula (I): It has less side-effects and a lower toxicity than ajmalicine itself. It is prepd. by the reaction of ajmalicine with 2 molar equivs. of nicotinic acid at ambient temp. in a lower alkanol.
FR7205969A 1971-02-22 1972-02-22 Ajmalicine nicotinate - antihypertensive Granted FR2126306A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT2086071 1971-02-22

Publications (2)

Publication Number Publication Date
FR2126306A1 true FR2126306A1 (en) 1972-10-06
FR2126306B1 FR2126306B1 (en) 1975-06-13

Family

ID=11173149

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7205969A Granted FR2126306A1 (en) 1971-02-22 1972-02-22 Ajmalicine nicotinate - antihypertensive

Country Status (2)

Country Link
ES (1) ES399252A1 (en)
FR (1) FR2126306A1 (en)

Also Published As

Publication number Publication date
FR2126306B1 (en) 1975-06-13
ES399252A1 (en) 1975-05-16

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Legal Events

Date Code Title Description
ST Notification of lapse