FR2106599A1 - Spiro-isoindoline cpds - analgesics and hypotensives - Google Patents

Spiro-isoindoline cpds - analgesics and hypotensives

Info

Publication number
FR2106599A1
FR2106599A1 FR7133152A FR7133152A FR2106599A1 FR 2106599 A1 FR2106599 A1 FR 2106599A1 FR 7133152 A FR7133152 A FR 7133152A FR 7133152 A FR7133152 A FR 7133152A FR 2106599 A1 FR2106599 A1 FR 2106599A1
Authority
FR
France
Prior art keywords
cpds
hypotensives
analgesics
isoindoline
spiro
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
FR7133152A
Other languages
French (fr)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz AG filed Critical Sandoz AG
Publication of FR2106599A1 publication Critical patent/FR2106599A1/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/10—Spiro-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/96—Spiro-condensed ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D219/00—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems
    • C07D219/04—Heterocyclic compounds containing acridine or hydrogenated acridine ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
    • C07D219/06—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10—Spiro-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/10—Spiro-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Cpds. of formula (I): (where Z is CH2; X is a direct bond, O, S, CH2S or NR10, where R10 = Me or Et; R is 1-3C alkyl; R1-R9 are H, Cl or 1-3C alkoxy, provided that not more than 2 are other than H) are prepd. by reduction of (I; Z = CO) pref. in an inert solvent and atmosphere. Cpds. (I) are analgesics (X = O, S or CH2S) and hypotensives (X = bond or NR10).
FR7133152A 1970-09-18 1971-09-15 Spiro-isoindoline cpds - analgesics and hypotensives Withdrawn FR2106599A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US7359670A 1970-09-18 1970-09-18

Publications (1)

Publication Number Publication Date
FR2106599A1 true FR2106599A1 (en) 1972-05-05

Family

ID=22114638

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7133152A Withdrawn FR2106599A1 (en) 1970-09-18 1971-09-15 Spiro-isoindoline cpds - analgesics and hypotensives

Country Status (2)

Country Link
DE (1) DE2146340A1 (en)
FR (1) FR2106599A1 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2022269145A1 (en) 2021-06-22 2022-12-29 Psa Automobiles Sa Management of a voltage converter control unit for a motor vehicle

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2022269145A1 (en) 2021-06-22 2022-12-29 Psa Automobiles Sa Management of a voltage converter control unit for a motor vehicle

Also Published As

Publication number Publication date
DE2146340A1 (en) 1972-03-30

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Legal Events

Date Code Title Description
ST Notification of lapse