FR2034994A1 - 3-carbamoyl-1-thia-isochroman-1,-dioxide - derivatives preparation - Google Patents

3-carbamoyl-1-thia-isochroman-1,-dioxide - derivatives preparation

Info

Publication number
FR2034994A1
FR2034994A1 FR7009311A FR7009311A FR2034994A1 FR 2034994 A1 FR2034994 A1 FR 2034994A1 FR 7009311 A FR7009311 A FR 7009311A FR 7009311 A FR7009311 A FR 7009311A FR 2034994 A1 FR2034994 A1 FR 2034994A1
Authority
FR
France
Prior art keywords
carbamoyl
dioxide
isochroman
thia
derivatives preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7009311A
Other languages
French (fr)
Other versions
FR2034994B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AWD Pharma GmbH and Co KG
Original Assignee
Arzneimittelwerk Dresden GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Arzneimittelwerk Dresden GmbH filed Critical Arzneimittelwerk Dresden GmbH
Publication of FR2034994A1 publication Critical patent/FR2034994A1/en
Application granted granted Critical
Publication of FR2034994B1 publication Critical patent/FR2034994B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D327/00—Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms
    • C07D327/02—Heterocyclic compounds containing rings having oxygen and sulfur atoms as the only ring hetero atoms one oxygen atom and one sulfur atom
    • C07D327/06—Six-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
    • A61K31/39—Heterocyclic compounds having sulfur as a ring hetero atom having oxygen in the same ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

3-Carbamoyl-1-thia-isochroman-1,1-dioxide derivs. preparation. The title cpd. of general formula: (in which R1 and R2 is a lower alkyl residue and R3 is H or a lower alkyl gp.) and is prepd. by reacting with conc. H2SO4 at room temp., a cpd. of general formula: (where R4 is a carbonitrile or carbamoyl gp.). Pref. the deriv. is 3-carbamoyl-3-methyl-6,7-dimethoxy-1-thiisochroman-1.1-dioxide. Used pharmaceutically as anticonvulsant.
FR7009311A 1969-03-17 1970-03-16 3-carbamoyl-1-thia-isochroman-1,-dioxide - derivatives preparation Granted FR2034994A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DD13859769 1969-03-17

Publications (2)

Publication Number Publication Date
FR2034994A1 true FR2034994A1 (en) 1970-12-18
FR2034994B1 FR2034994B1 (en) 1974-04-12

Family

ID=5481041

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7009311A Granted FR2034994A1 (en) 1969-03-17 1970-03-16 3-carbamoyl-1-thia-isochroman-1,-dioxide - derivatives preparation

Country Status (11)

Country Link
AT (1) AT294847B (en)
BG (1) BG17562A3 (en)
CH (1) CH524627A (en)
CS (1) CS163363B1 (en)
DK (1) DK124206B (en)
EG (1) EG10526A (en)
FI (1) FI49974C (en)
FR (1) FR2034994A1 (en)
PL (1) PL80537B1 (en)
RO (1) RO58333A2 (en)
SE (1) SE363337B (en)

Also Published As

Publication number Publication date
FR2034994B1 (en) 1974-04-12
RO58333A2 (en) 1975-05-20
EG10526A (en) 1976-01-31
FI49974B (en) 1975-07-31
DE2011025A1 (en) 1970-10-08
FI49974C (en) 1975-11-10
PL80537B1 (en) 1975-08-30
SE363337B (en) 1974-01-14
AT294847B (en) 1971-11-15
CH524627A (en) 1972-06-30
DK124206B (en) 1972-09-25
BG17562A3 (en) 1973-11-10
CS163363B1 (en) 1975-09-15

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Legal Events

Date Code Title Description
ST Notification of lapse