FR2143539A1 - 2-benzylidene-3-hydroxy-3-methylpyrrolidinium iodides - with hypotensive and spasmolytic activity - Google Patents
2-benzylidene-3-hydroxy-3-methylpyrrolidinium iodides - with hypotensive and spasmolytic activityInfo
- Publication number
- FR2143539A1 FR2143539A1 FR7123472A FR7123472A FR2143539A1 FR 2143539 A1 FR2143539 A1 FR 2143539A1 FR 7123472 A FR7123472 A FR 7123472A FR 7123472 A FR7123472 A FR 7123472A FR 2143539 A1 FR2143539 A1 FR 2143539A1
- Authority
- FR
- France
- Prior art keywords
- methylpyrrolidinium
- hypotensive
- iodides
- benzylidene
- hydroxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- PBKZICUUPMVWRS-UHFFFAOYSA-N 2-benzylidene-3-methylpyrrolidin-1-ium-3-ol iodide Chemical class [I-].C(C1=CC=CC=C1)=C1[NH2+]CCC1(C)O PBKZICUUPMVWRS-UHFFFAOYSA-N 0.000 title 1
- 208000001953 Hypotension Diseases 0.000 title 1
- 208000021822 hypotensive Diseases 0.000 title 1
- 230000001077 hypotensive effect Effects 0.000 title 1
- 230000002048 spasmolytic effect Effects 0.000 title 1
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 abstract 3
- HLKCQDCFCONHBT-UHFFFAOYSA-N 5-amino-3-methyl-1-phenylpent-1-yn-3-ol Chemical class NCCC(C#CC1=CC=CC=C1)(O)C HLKCQDCFCONHBT-UHFFFAOYSA-N 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- XMBWDFGMSWQBCA-UHFFFAOYSA-N hydrogen iodide Chemical compound I XMBWDFGMSWQBCA-UHFFFAOYSA-N 0.000 abstract 1
- 230000003472 neutralizing effect Effects 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- -1 pyrrolidino, piperidino Chemical group 0.000 abstract 1
- 238000010992 reflux Methods 0.000 abstract 1
- 238000006798 ring closing metathesis reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pyrrole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7123472A FR2143539A1 (en) | 1971-06-28 | 1971-06-28 | 2-benzylidene-3-hydroxy-3-methylpyrrolidinium iodides - with hypotensive and spasmolytic activity |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7123472A FR2143539A1 (en) | 1971-06-28 | 1971-06-28 | 2-benzylidene-3-hydroxy-3-methylpyrrolidinium iodides - with hypotensive and spasmolytic activity |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2143539A1 true FR2143539A1 (en) | 1973-02-09 |
| FR2143539B1 FR2143539B1 (enExample) | 1974-08-23 |
Family
ID=9079423
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7123472A Granted FR2143539A1 (en) | 1971-06-28 | 1971-06-28 | 2-benzylidene-3-hydroxy-3-methylpyrrolidinium iodides - with hypotensive and spasmolytic activity |
Country Status (1)
| Country | Link |
|---|---|
| FR (1) | FR2143539A1 (enExample) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6121296A (en) * | 1992-11-04 | 2000-09-19 | Albert Einstein College Of Medicine Of Yeshiva University | Transition-state inhibitors for nucleoside hydrolase and transferase reactions |
| CN103254120A (zh) * | 2013-05-16 | 2013-08-21 | 中国科学院化学研究所 | 一种螺环氮杂糖季铵盐化合物及其制备方法与应用 |
-
1971
- 1971-06-28 FR FR7123472A patent/FR2143539A1/fr active Granted
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6121296A (en) * | 1992-11-04 | 2000-09-19 | Albert Einstein College Of Medicine Of Yeshiva University | Transition-state inhibitors for nucleoside hydrolase and transferase reactions |
| CN103254120A (zh) * | 2013-05-16 | 2013-08-21 | 中国科学院化学研究所 | 一种螺环氮杂糖季铵盐化合物及其制备方法与应用 |
Also Published As
| Publication number | Publication date |
|---|---|
| FR2143539B1 (enExample) | 1974-08-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |