FR2105119A1 - Analgesic piperidino ethanol deriv - 1-parabenzyloxyphenyl -2-4-benzylpiperidinoethanol - Google Patents

Analgesic piperidino ethanol deriv - 1-parabenzyloxyphenyl -2-4-benzylpiperidinoethanol

Info

Publication number
FR2105119A1
FR2105119A1 FR7035138A FR7035138A FR2105119A1 FR 2105119 A1 FR2105119 A1 FR 2105119A1 FR 7035138 A FR7035138 A FR 7035138A FR 7035138 A FR7035138 A FR 7035138A FR 2105119 A1 FR2105119 A1 FR 2105119A1
Authority
FR
France
Prior art keywords
parabenzyloxyphenyl
benzylpiperidinoethanol
deriv
analgesic
piperidino
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7035138A
Other languages
French (fr)
Other versions
FR2105119B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Synthelabo SA
Original Assignee
Synthelabo SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synthelabo SA filed Critical Synthelabo SA
Priority to FR7035138A priority Critical patent/FR2105119A1/en
Publication of FR2105119A1 publication Critical patent/FR2105119A1/en
Application granted granted Critical
Publication of FR2105119B1 publication Critical patent/FR2105119B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/30—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by doubly bound oxygen or sulfur atoms or by two oxygen or sulfur atoms singly bound to the same carbon atom
    • C07D211/32—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by doubly bound oxygen or sulfur atoms or by two oxygen or sulfur atoms singly bound to the same carbon atom by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/63—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by introduction of halogen; by substitution of halogen atoms by other halogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/10—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms
    • C07D211/14—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms with hydrocarbon or substituted hydrocarbon radicals attached to the ring nitrogen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

Title cpds is of formula (I): and may be prepd by reduction of 1-(p-benzyloxyphenyl)-2-(4-benzylpiperidino) acetophenone (II), itself prepd by the condensation of 4-benzyl piperidine with p-benzyloxy-alpha-bromoacetophenone.
FR7035138A 1970-09-29 1970-09-29 Analgesic piperidino ethanol deriv - 1-parabenzyloxyphenyl -2-4-benzylpiperidinoethanol Granted FR2105119A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR7035138A FR2105119A1 (en) 1970-09-29 1970-09-29 Analgesic piperidino ethanol deriv - 1-parabenzyloxyphenyl -2-4-benzylpiperidinoethanol

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7035138A FR2105119A1 (en) 1970-09-29 1970-09-29 Analgesic piperidino ethanol deriv - 1-parabenzyloxyphenyl -2-4-benzylpiperidinoethanol

Publications (2)

Publication Number Publication Date
FR2105119A1 true FR2105119A1 (en) 1972-04-28
FR2105119B1 FR2105119B1 (en) 1974-07-12

Family

ID=9061987

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7035138A Granted FR2105119A1 (en) 1970-09-29 1970-09-29 Analgesic piperidino ethanol deriv - 1-parabenzyloxyphenyl -2-4-benzylpiperidinoethanol

Country Status (1)

Country Link
FR (1) FR2105119A1 (en)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2471374A1 (en) * 1979-12-07 1981-06-19 Cosmos Enterprise NOVEL PROCESS FOR THE PREPARATION OF 1- (4-HYDROXYPHENYL) -2- (4-BENZYLPIPERIDINO) -PROPANOL AND ITS ACID ADDITION SALTS
FR2534580A1 (en) * 1982-10-13 1984-04-20 Synthelabo PHENYL-1 PIPERIDINO-2 PROPANOL DERIVATIVES, THEIR PREPARATION, AND MEDICINES THAT CONTAIN THEM
EP0232423A1 (en) * 1985-07-24 1987-08-19 Grelan Pharmaceutical Co., Ltd. Circulation improving agent
EP0288563A1 (en) * 1986-09-30 1988-11-02 Eisai Co., Ltd. Cyclic amine derivatives
JP2573195B2 (en) * 1986-09-30 1997-01-22 エーザイ株式会社 Cyclic amine derivative
US7786140B2 (en) * 2003-09-25 2010-08-31 Shionogi & Co., Ltd. Piperidine derivative having NMDA receptor antagonistic activity

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2471374A1 (en) * 1979-12-07 1981-06-19 Cosmos Enterprise NOVEL PROCESS FOR THE PREPARATION OF 1- (4-HYDROXYPHENYL) -2- (4-BENZYLPIPERIDINO) -PROPANOL AND ITS ACID ADDITION SALTS
FR2534580A1 (en) * 1982-10-13 1984-04-20 Synthelabo PHENYL-1 PIPERIDINO-2 PROPANOL DERIVATIVES, THEIR PREPARATION, AND MEDICINES THAT CONTAIN THEM
EP0109317A2 (en) * 1982-10-13 1984-05-23 Synthelabo Phenyl-1-piperidino-2-propanol derivatives, their preparation and medicaments containing them
EP0109317A3 (en) * 1982-10-13 1984-08-08 Synthelabo Phenyl-1-piperidino-2-propanol derivatives, their preparation and medicaments containing them
EP0232423A1 (en) * 1985-07-24 1987-08-19 Grelan Pharmaceutical Co., Ltd. Circulation improving agent
EP0232423A4 (en) * 1985-07-24 1987-12-09 Grelan Pharmaceutical Co Circulation improving agent.
EP0288563A1 (en) * 1986-09-30 1988-11-02 Eisai Co., Ltd. Cyclic amine derivatives
EP0288563A4 (en) * 1986-09-30 1990-09-26 Eisai Co., Ltd. Cyclic amine derivatives
JP2573195B2 (en) * 1986-09-30 1997-01-22 エーザイ株式会社 Cyclic amine derivative
US7786140B2 (en) * 2003-09-25 2010-08-31 Shionogi & Co., Ltd. Piperidine derivative having NMDA receptor antagonistic activity

Also Published As

Publication number Publication date
FR2105119B1 (en) 1974-07-12

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ST Notification of lapse