FR2124066A1 - Alpha-piperazino-beta-benzoylpropionic acids - - with analgesic,analeptic,anticonvulsant and other activity - Google Patents

Alpha-piperazino-beta-benzoylpropionic acids - - with analgesic,analeptic,anticonvulsant and other activity

Info

Publication number
FR2124066A1
FR2124066A1 FR7103521A FR7103521A FR2124066A1 FR 2124066 A1 FR2124066 A1 FR 2124066A1 FR 7103521 A FR7103521 A FR 7103521A FR 7103521 A FR7103521 A FR 7103521A FR 2124066 A1 FR2124066 A1 FR 2124066A1
Authority
FR
France
Prior art keywords
analeptic
piperazino
analgesic
activity
anticonvulsant
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7103521A
Other languages
French (fr)
Other versions
FR2124066B1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Synthelabo SA
Original Assignee
Delalande SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Delalande SA filed Critical Delalande SA
Priority to FR7103521A priority Critical patent/FR2124066A1/en
Publication of FR2124066A1 publication Critical patent/FR2124066A1/en
Application granted granted Critical
Publication of FR2124066B1 publication Critical patent/FR2124066B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/145—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Cpds. of formula where R is 1-4C alkyl, -CH2CO2R' where R' is 1-4C alkyl or where R2, R3 are H, 1-4C alkyl or R2, R3 and the attached N-atom may be pyrrolidino, piperazino or morpholino. Cpds. have analgesic, analeptic, anticonvusant, anxiolytic, hypotensive, vasodilator and diuretic activity. Pref. by reaction of 2-benzoylacrylic acid with 1-substd. piperazines. Cpds. have low toxicity.
FR7103521A 1971-02-03 1971-02-03 Alpha-piperazino-beta-benzoylpropionic acids - - with analgesic,analeptic,anticonvulsant and other activity Granted FR2124066A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR7103521A FR2124066A1 (en) 1971-02-03 1971-02-03 Alpha-piperazino-beta-benzoylpropionic acids - - with analgesic,analeptic,anticonvulsant and other activity

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7103521A FR2124066A1 (en) 1971-02-03 1971-02-03 Alpha-piperazino-beta-benzoylpropionic acids - - with analgesic,analeptic,anticonvulsant and other activity

Publications (2)

Publication Number Publication Date
FR2124066A1 true FR2124066A1 (en) 1972-09-22
FR2124066B1 FR2124066B1 (en) 1974-04-12

Family

ID=9071291

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7103521A Granted FR2124066A1 (en) 1971-02-03 1971-02-03 Alpha-piperazino-beta-benzoylpropionic acids - - with analgesic,analeptic,anticonvulsant and other activity

Country Status (1)

Country Link
FR (1) FR2124066A1 (en)

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
NEANT *

Also Published As

Publication number Publication date
FR2124066B1 (en) 1974-04-12

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Legal Events

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