FR2142809A1 - 3-hydroxy-3-methyl-2-methylene pyrrolidinium iodides - with vasodilator, hypotensive and analgesic activity - Google Patents
3-hydroxy-3-methyl-2-methylene pyrrolidinium iodides - with vasodilator, hypotensive and analgesic activityInfo
- Publication number
- FR2142809A1 FR2142809A1 FR7123262A FR7123262A FR2142809A1 FR 2142809 A1 FR2142809 A1 FR 2142809A1 FR 7123262 A FR7123262 A FR 7123262A FR 7123262 A FR7123262 A FR 7123262A FR 2142809 A1 FR2142809 A1 FR 2142809A1
- Authority
- FR
- France
- Prior art keywords
- methyl
- vasodilator
- hypotensive
- iodides
- hydroxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
Abstract
Cpds. of formula where R1, R2 are alkyl (C1-4) or R1+R2 and the attached N-atom are morpholino, pyrrolidino or piperidino. The cpds. are prepd. by cyclisation of 5-t-amino-3-methyl-1-pentyn-3-ols and neutralisation of the tert. amine with hydriodic acid.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR7123262A FR2142809A1 (en) | 1971-06-25 | 1971-06-25 | 3-hydroxy-3-methyl-2-methylene pyrrolidinium iodides - with vasodilator, hypotensive and analgesic activity |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR7123262A FR2142809A1 (en) | 1971-06-25 | 1971-06-25 | 3-hydroxy-3-methyl-2-methylene pyrrolidinium iodides - with vasodilator, hypotensive and analgesic activity |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2142809A1 true FR2142809A1 (en) | 1973-02-02 |
FR2142809B1 FR2142809B1 (en) | 1974-08-30 |
Family
ID=9079334
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7123262A Granted FR2142809A1 (en) | 1971-06-25 | 1971-06-25 | 3-hydroxy-3-methyl-2-methylene pyrrolidinium iodides - with vasodilator, hypotensive and analgesic activity |
Country Status (1)
Country | Link |
---|---|
FR (1) | FR2142809A1 (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4208423A (en) * | 1978-11-24 | 1980-06-17 | Syntex Inc. | Anticholinergic bronchodilators |
CN103254120A (en) * | 2013-05-16 | 2013-08-21 | 中国科学院化学研究所 | Spiro-azasugar quaternary ammonium salt compound, and preparation method and application thereof |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1144656A (en) * | 1966-11-08 | 1969-03-05 | Fujisawa Pharmaceutical Co | 1,1-diethyl-2-methyl-3-diphenylmethylenepyrrolidinium halide compositions |
CH486449A (en) * | 1964-01-14 | 1970-02-28 | Delmar Chem | Process for preparing phthalimidoacylamido-benzophenones |
-
1971
- 1971-06-25 FR FR7123262A patent/FR2142809A1/en active Granted
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH486449A (en) * | 1964-01-14 | 1970-02-28 | Delmar Chem | Process for preparing phthalimidoacylamido-benzophenones |
GB1144656A (en) * | 1966-11-08 | 1969-03-05 | Fujisawa Pharmaceutical Co | 1,1-diethyl-2-methyl-3-diphenylmethylenepyrrolidinium halide compositions |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4208423A (en) * | 1978-11-24 | 1980-06-17 | Syntex Inc. | Anticholinergic bronchodilators |
CN103254120A (en) * | 2013-05-16 | 2013-08-21 | 中国科学院化学研究所 | Spiro-azasugar quaternary ammonium salt compound, and preparation method and application thereof |
Also Published As
Publication number | Publication date |
---|---|
FR2142809B1 (en) | 1974-08-30 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ST | Notification of lapse |