FR2135249B1 - - Google Patents
Info
- Publication number
- FR2135249B1 FR2135249B1 FR7215673A FR7215673A FR2135249B1 FR 2135249 B1 FR2135249 B1 FR 2135249B1 FR 7215673 A FR7215673 A FR 7215673A FR 7215673 A FR7215673 A FR 7215673A FR 2135249 B1 FR2135249 B1 FR 2135249B1
- Authority
- FR
- France
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/06—Pyrimidine radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/12—Triazine radicals
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE2122991A DE2122991C2 (de) | 1971-05-04 | 1971-05-04 | Verfahren zur Herstellung von Cytosin- und 6-Azacytosinnucleosiden |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2135249A1 FR2135249A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1972-12-15 |
| FR2135249B1 true FR2135249B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1975-10-17 |
Family
ID=5807376
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7215673A Expired FR2135249B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1971-05-04 | 1972-05-03 |
Country Status (8)
Families Citing this family (42)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4090021A (en) * | 1971-10-08 | 1978-05-16 | Schering Aktiengesellschaft | Process for the production of N6 -substituted adenosine nucleotides and products resulting therefrom |
| DE2508312A1 (de) * | 1975-02-24 | 1976-09-02 | Schering Ag | Neues verfahren zur herstellung von nucleosiden |
| DE2514275A1 (de) * | 1975-03-27 | 1976-10-14 | Schering Ag | Verfahren zur herstellung von n- (polysaccharidyl)-stickstoffheterocyclen, insbesondere von pyrimidin- oder purinbasen |
| US4118484A (en) * | 1976-03-29 | 1978-10-03 | The Upjohn Company | Method of treating rheumatoid arthritis |
| DE2621645C3 (de) * | 1976-05-13 | 1981-08-06 | Schering Ag Berlin Und Bergkamen, 1000 Berlin | Verfahren zur Herstellung von Aminoderivaten von N-Heterocyclen |
| GB1601020A (en) | 1978-04-24 | 1981-10-21 | Stichting Grega Vzw | 2'-deoxy-5 (2-halogenovinyl)-uridines |
| US4267171A (en) * | 1979-07-02 | 1981-05-12 | The Regents Of The University Of California | C-5 Substituted cytosine nucleosides |
| US4754026A (en) * | 1985-06-04 | 1988-06-28 | Takeda Chemical Industries, Ltd. | Conversion of uracil derivatives to cytosine derivatives |
| FR2590255B1 (fr) * | 1985-11-19 | 1987-12-24 | Rhone Poulenc Sante | Procede de preparation de derives de la pteridine |
| US4788181A (en) * | 1986-09-29 | 1988-11-29 | The United States Of America As Represented By The Department Of Health And Human Services | 5-substituted-2',3'-dideoxycytidine compounds with anti-HTLV-III activity |
| US6432924B1 (en) | 1993-12-26 | 2002-08-13 | East Carolina University | Method of treating disorders characterized by overexpression of cytidine deaminase or deoxycytidine deaminase |
| US8236493B2 (en) * | 1994-10-21 | 2012-08-07 | Affymetrix, Inc. | Methods of enzymatic discrimination enhancement and surface-bound double-stranded DNA |
| US6974666B1 (en) * | 1994-10-21 | 2005-12-13 | Appymetric, Inc. | Methods of enzymatic discrimination enhancement and surface-bound double-stranded DNA |
| AU728377C (en) * | 1995-12-22 | 2003-10-30 | East Carolina University | Method of treating disorders characterized by overexpression of cytidine deaminase or deoxycytidine deaminase |
| US20010018514A1 (en) * | 1998-07-31 | 2001-08-30 | Mcgall Glenn H. | Nucleic acid labeling compounds |
| US6864059B2 (en) * | 1996-01-23 | 2005-03-08 | Affymetrix, Inc. | Biotin containing C-glycoside nucleic acid labeling compounds |
| US7291463B2 (en) * | 1996-01-23 | 2007-11-06 | Affymetrix, Inc. | Nucleic acid labeling compounds |
| US7282327B2 (en) * | 1996-01-23 | 2007-10-16 | Affymetrix, Inc. | Nucleic acid labeling compounds |
| EP0880598A4 (en) | 1996-01-23 | 2005-02-23 | Affymetrix Inc | RAPID EVALUATION OF NUCLEIC ACID ABUNDANCE DIFFERENCE, WITH A HIGH-DENSITY OLIGONUCLEOTIDE SYSTEM |
| US6965020B2 (en) | 1996-01-23 | 2005-11-15 | Affymetrix, Inc. | Nucleic acid labeling compounds |
| US20040210045A1 (en) * | 1996-01-23 | 2004-10-21 | Mcgall Glenn | Nucleic acid labeling compounds |
| US7423143B2 (en) * | 1996-01-23 | 2008-09-09 | Affymetrix. Inc. | Nucleic acid labeling compounds |
| MY164523A (en) | 2000-05-23 | 2017-12-29 | Univ Degli Studi Cagliari | Methods and compositions for treating hepatitis c virus |
| EA007867B1 (ru) | 2000-05-26 | 2007-02-27 | Айденикс (Кайман) Лимитед | Композиции для лечения флавивирусных и пестивирусных инфекций и способы их применения |
| US20030008841A1 (en) * | 2000-08-30 | 2003-01-09 | Rene Devos | Anti-HCV nucleoside derivatives |
| CA2440615A1 (en) | 2001-03-12 | 2002-09-19 | Affymetrix, Inc. | Nucleic acid labeling compounds |
| NZ537662A (en) | 2002-06-28 | 2007-10-26 | Idenix Cayman Ltd | 2'-C-methyl-3'-O-L-valine ester ribofuranosyl cytidine for treatment of flaviviridae infections |
| MXPA04012802A (es) | 2002-06-28 | 2005-04-19 | Idenix Cayman Ltd | Ester 2'-c-metil-3'-o-l-valina de ribofuranosil-citidina para el tratamiento de infecciones por flaviviridae. |
| US7608600B2 (en) * | 2002-06-28 | 2009-10-27 | Idenix Pharmaceuticals, Inc. | Modified 2′ and 3′-nucleoside prodrugs for treating Flaviviridae infections |
| RU2005118421A (ru) | 2002-11-15 | 2006-01-20 | Айденикс (Кайман) Лимитед (Ky) | 2'-разветвленные нуклеозиды и мутация flaviviridae |
| PL377287A1 (pl) | 2002-12-12 | 2006-01-23 | Idenix (Cayman) Limited | Sposób wytwarzania 2'-rozgałęzionych nukleozydów |
| US6887855B2 (en) * | 2003-03-17 | 2005-05-03 | Pharmion Corporation | Forms of 5-azacytidine |
| US7038038B2 (en) * | 2003-03-17 | 2006-05-02 | Pharmion Corporation | Synthesis of 5-azacytidine |
| US6943249B2 (en) * | 2003-03-17 | 2005-09-13 | Ash Stevens, Inc. | Methods for isolating crystalline Form I of 5-azacytidine |
| CN101415719A (zh) * | 2003-03-20 | 2009-04-22 | 微生物化学及药品有限公司 | 生产2’-脱氧-β-L-核苷的方法 |
| CN1812995A (zh) | 2003-04-28 | 2006-08-02 | 艾登尼科斯（开曼）有限公司 | 工业化规模的核苷合成 |
| AU2004254620A1 (en) * | 2003-06-30 | 2005-01-13 | Idenix (Cayman) Limited | Synthesis of beta-L-2-deoxy nucleosides |
| JP4516863B2 (ja) * | 2005-03-11 | 2010-08-04 | 株式会社ケンウッド | 音声合成装置、音声合成方法及びプログラム |
| US7781576B2 (en) | 2005-12-23 | 2010-08-24 | Idenix Pharmaceuticals, Inc. | Process for preparing a synthetic intermediate for preparation of branched nucleosides |
| CN101877964A (zh) * | 2007-09-26 | 2010-11-03 | 西乃山医学院 | 氮杂胞苷类似物及其用途 |
| DK3782612T3 (da) * | 2008-05-15 | 2024-01-15 | Celgene Corp | Orale formuleringer af cytidinanaloger og fremgangsmåder til anvendelse deraf |
| JP6289361B2 (ja) | 2011-03-31 | 2018-03-07 | セルジーン インターナショナル サルル | ５−アザシチジンの合成 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1030970A (en) * | 1964-05-15 | 1966-05-25 | Inst Mikrobiologii Im Akad D K | Method for the preparation of 2', 3', 5'-tri-o-acyl-6-azacytidines |
| US3328389A (en) * | 1964-08-07 | 1967-06-27 | Sankyo Co | Process for preparing nucleotide derivatives |
| US3328388A (en) * | 1964-09-02 | 1967-06-27 | Merck & Co Inc | Arabinofuranosyl pyrimidines and methods of preparing same |
| US3354160A (en) * | 1965-07-22 | 1967-11-21 | Hoffmann La Roche | Tri-lower alkyl-silyl-5-fluoropyrimidines |
| US3346561A (en) * | 1965-10-24 | 1967-10-10 | Merck & Co Inc | Pyrimidine 3-deoxynucleosides |
| US3404144A (en) * | 1965-12-23 | 1968-10-01 | Research Corp | 1-beta-d-arabinofuranosyl-5-fluorocytosine compounds |
| DE1795357A1 (de) * | 1968-09-18 | 1972-01-05 | Schering Ag | 2-Thio-pyrimidin-nucleoside |
| US3721664A (en) * | 1970-01-27 | 1973-03-20 | Hoffmann La Roche | Preparation of 5-cytosine nucleosides |
-
1971
- 1971-05-04 DE DE2122991A patent/DE2122991C2/de not_active Expired
-
1972
- 1972-04-26 CS CS2827A patent/CS171723B2/cs unknown
- 1972-05-01 GB GB2011572A patent/GB1395764A/en not_active Expired
- 1972-05-03 FR FR7215673A patent/FR2135249B1/fr not_active Expired
- 1972-05-03 US US250045A patent/US3891623A/en not_active Expired - Lifetime
- 1972-05-04 CH CH663072A patent/CH579585A5/xx not_active IP Right Cessation
- 1972-05-04 NL NL7206058A patent/NL7206058A/xx not_active Application Discontinuation
- 1972-05-04 BE BE783026A patent/BE783026A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NL7206058A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1972-11-07 |
| US3891623A (en) | 1975-06-24 |
| DE2122991C2 (de) | 1982-06-09 |
| GB1395764A (en) | 1975-05-29 |
| CS171723B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1976-10-29 |
| BE783026A (fr) | 1972-11-06 |
| DE2122991A1 (de) | 1972-11-16 |
| CH579585A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1976-09-15 |
| FR2135249A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1972-12-15 |
Similar Documents
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |