FR2123515A1 - 5-alpha-hydro(pero)xy-oestr-6-enes and ethers and esters - - with progestational, ovulation-inhibiting and oestrogenic activity - Google Patents
5-alpha-hydro(pero)xy-oestr-6-enes and ethers and esters - - with progestational, ovulation-inhibiting and oestrogenic activityInfo
- Publication number
- FR2123515A1 FR2123515A1 FR7202928A FR7202928A FR2123515A1 FR 2123515 A1 FR2123515 A1 FR 2123515A1 FR 7202928 A FR7202928 A FR 7202928A FR 7202928 A FR7202928 A FR 7202928A FR 2123515 A1 FR2123515 A1 FR 2123515A1
- Authority
- FR
- France
- Prior art keywords
- progestational
- ovulation
- inhibiting
- alkyl
- oestr
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Steroid Compounds (AREA)
Abstract
Cpds. of formula (I):- (where R1 = 1-4C alkyl; R2 is O or (betaP)(alphaQ), where P is free, esterified or etherified OH and Q is H, alkyl, alkenyl or alkynyl (all =4C); R3 is OH, alkoxy, acyloxy, H, alkyl or acyl) are prepd. by reaction of a cpd. (II), with activated oxygen to give the DELTA6-5alpha-hydroperoxy steroid which can then be reduced to the DELTA6-5alpha-hydroxy-steroid and/or substituents introduced and posn. 17 and/or the OOH or OH gps. esterified or etherified. Oxygenation can be effected by irradiating (II) with visible or UV light in the presence of O2 and a sensitiser or by heating with a substd. phosphite-ozonide, esp. triphenyl phosphite ozonide. Cpds. (I) have progestational ovulation-inhibiting, pregnancy-maintaining and oestrogenic activity.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| NL7101102A NL7101102A (en) | 1971-01-28 | 1971-01-28 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| FR2123515A1 true FR2123515A1 (en) | 1972-09-08 |
Family
ID=19812345
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7202928A Withdrawn FR2123515A1 (en) | 1971-01-28 | 1972-01-28 | 5-alpha-hydro(pero)xy-oestr-6-enes and ethers and esters - - with progestational, ovulation-inhibiting and oestrogenic activity |
Country Status (9)
| Country | Link |
|---|---|
| AR (1) | AR194220A1 (en) |
| AU (1) | AU3813772A (en) |
| BE (1) | BE778645A (en) |
| DE (1) | DE2203886A1 (en) |
| ES (1) | ES399242A1 (en) |
| FR (1) | FR2123515A1 (en) |
| IL (1) | IL38579A0 (en) |
| NL (1) | NL7101102A (en) |
| ZA (1) | ZA72301B (en) |
-
1971
- 1971-01-28 NL NL7101102A patent/NL7101102A/xx unknown
-
1972
- 1972-01-17 ZA ZA720301A patent/ZA72301B/en unknown
- 1972-01-18 IL IL38579A patent/IL38579A0/en unknown
- 1972-01-20 AU AU38137/72A patent/AU3813772A/en not_active Expired
- 1972-01-25 AR AR240211A patent/AR194220A1/en active
- 1972-01-27 ES ES399242A patent/ES399242A1/en not_active Expired
- 1972-01-27 DE DE19722203886 patent/DE2203886A1/en active Pending
- 1972-01-28 BE BE778645A patent/BE778645A/en unknown
- 1972-01-28 FR FR7202928A patent/FR2123515A1/en not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| ZA72301B (en) | 1972-09-27 |
| NL7101102A (en) | 1972-08-01 |
| ES399242A1 (en) | 1974-12-16 |
| AR194220A1 (en) | 1973-06-29 |
| IL38579A0 (en) | 1972-03-28 |
| DE2203886A1 (en) | 1972-08-17 |
| AU3813772A (en) | 1973-07-26 |
| BE778645A (en) | 1972-05-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |