FR2252090A1 - 3,3-Diphenyl-2-indolinone laxatives - with 4-propoxy substit. on one phenyl, with reduced gastrointestinal irritancy - Google Patents

3,3-Diphenyl-2-indolinone laxatives - with 4-propoxy substit. on one phenyl, with reduced gastrointestinal irritancy

Info

Publication number
FR2252090A1
FR2252090A1 FR7342361A FR7342361A FR2252090A1 FR 2252090 A1 FR2252090 A1 FR 2252090A1 FR 7342361 A FR7342361 A FR 7342361A FR 7342361 A FR7342361 A FR 7342361A FR 2252090 A1 FR2252090 A1 FR 2252090A1
Authority
FR
France
Prior art keywords
indolinone
diphenyl
substit
laxatives
propoxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
FR7342361A
Other languages
French (fr)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to FR7342361A priority Critical patent/FR2252090A1/en
Priority to JP11722274A priority patent/JPS5083370A/ja
Priority to DE19742451592 priority patent/DE2451592A1/en
Priority to BE150039A priority patent/BE821662A/en
Priority to ES432262A priority patent/ES432262A1/en
Publication of FR2252090A1 publication Critical patent/FR2252090A1/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/32—Oxygen atoms
    • C07D209/34—Oxygen atoms in position 2

Abstract

of formula (I): (where R is OH, acetoxy, or -O.CH2CH2CH2.SO3H; M is an alkali metal or alkaline earth cation esp. Na), are hexatives with no irritant action on the gastrointestinal micosa. (I) are prepd. by treating 3,3-diphenyl-2-indolinone with propanesultone (R = OH or -OCH2CH2CH2.SO3H) in e.g. methanol. Treatment of the indolinone (I; R=OH) with acetic anhydride gives (I; R = acetoxy).
FR7342361A 1973-11-28 1973-11-28 3,3-Diphenyl-2-indolinone laxatives - with 4-propoxy substit. on one phenyl, with reduced gastrointestinal irritancy Withdrawn FR2252090A1 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
FR7342361A FR2252090A1 (en) 1973-11-28 1973-11-28 3,3-Diphenyl-2-indolinone laxatives - with 4-propoxy substit. on one phenyl, with reduced gastrointestinal irritancy
JP11722274A JPS5083370A (en) 1973-11-28 1974-10-14
DE19742451592 DE2451592A1 (en) 1973-11-28 1974-10-30 NEW ETHERS AND ESTERS OF 3,3-DIPHENOL2-INDOLINONE AND THE PROCESS FOR THEIR PRODUCTION
BE150039A BE821662A (en) 1973-11-28 1974-10-30 NEW ETHERS AND ESTERS OF 3,3-DIPHENOL-2-INDOLINONE AND PROCESS FOR THEIR PREPARATION
ES432262A ES432262A1 (en) 1973-11-28 1974-11-26 Procedure for obtaining eteres and esters of 3, 3- difenol-2-indolinone. (Machine-translation by Google Translate, not legally binding)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7342361A FR2252090A1 (en) 1973-11-28 1973-11-28 3,3-Diphenyl-2-indolinone laxatives - with 4-propoxy substit. on one phenyl, with reduced gastrointestinal irritancy

Publications (1)

Publication Number Publication Date
FR2252090A1 true FR2252090A1 (en) 1975-06-20

Family

ID=9128388

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7342361A Withdrawn FR2252090A1 (en) 1973-11-28 1973-11-28 3,3-Diphenyl-2-indolinone laxatives - with 4-propoxy substit. on one phenyl, with reduced gastrointestinal irritancy

Country Status (5)

Country Link
JP (1) JPS5083370A (en)
BE (1) BE821662A (en)
DE (1) DE2451592A1 (en)
ES (1) ES432262A1 (en)
FR (1) FR2252090A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3529994A1 (en) * 1985-08-22 1987-02-26 Hoechst Ag INDOLINE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF, MEDICINAL PRODUCTS CONTAINING THEM AND THE USE THEREOF
WO2010109008A1 (en) 2009-03-26 2010-09-30 Topotarget A/S Prodrugs of substituted 3-(4-hydroxyphenyl)-indolin-2-ones

Also Published As

Publication number Publication date
JPS5083370A (en) 1975-07-05
DE2451592A1 (en) 1975-06-05
BE821662A (en) 1975-02-17
ES432262A1 (en) 1977-01-01

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Legal Events

Date Code Title Description
ST Notification of lapse