FR2115454A1 - Hormonal delta-4-6, 7-dimethyl steroids - prepd by dehydration of 5-hydroxy cpds - Google Patents

Hormonal delta-4-6, 7-dimethyl steroids - prepd by dehydration of 5-hydroxy cpds

Info

Publication number
FR2115454A1
FR2115454A1 FR7142546A FR7142546A FR2115454A1 FR 2115454 A1 FR2115454 A1 FR 2115454A1 FR 7142546 A FR7142546 A FR 7142546A FR 7142546 A FR7142546 A FR 7142546A FR 2115454 A1 FR2115454 A1 FR 2115454A1
Authority
FR
France
Prior art keywords
prepd
hormonal
dehydration
delta
cpds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
FR7142546A
Other languages
French (fr)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Organon NV
Original Assignee
Organon NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Organon NV filed Critical Organon NV
Publication of FR2115454A1 publication Critical patent/FR2115454A1/en
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
    • C07J31/006—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J51/00—Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)

Abstract

Cpds. of formula: (I):- (where R1 = H2 or O; R2 = 1-4C alkyl; R3 = O or beta-OX(alpha-Y), where X = H, acyl or an ether gp., and Y = H or 1-6C alkyl, alkenyl or alkynyl) are prepd. by dehydration of (II):- while isomerising the 6 beta-Me group, and opt. eliminating the 3-keto gp., pref. by thioketalisation and reduction with alkali metal and liq. NH3, and/or introducing other gps. into posn-17. (I) are novel cpds. with hormonal, esp. ovulation inhibiting, oestrogenic, anabolic and androgenic activity.
FR7142546A 1970-11-28 1971-11-26 Hormonal delta-4-6, 7-dimethyl steroids - prepd by dehydration of 5-hydroxy cpds Withdrawn FR2115454A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NL7017428A NL7017428A (en) 1970-11-28 1970-11-28

Publications (1)

Publication Number Publication Date
FR2115454A1 true FR2115454A1 (en) 1972-07-07

Family

ID=19811666

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7142546A Withdrawn FR2115454A1 (en) 1970-11-28 1971-11-26 Hormonal delta-4-6, 7-dimethyl steroids - prepd by dehydration of 5-hydroxy cpds

Country Status (7)

Country Link
AU (1) AU3545671A (en)
BE (1) BE775052A (en)
DE (1) DE2158837A1 (en)
ES (1) ES397385A1 (en)
FR (1) FR2115454A1 (en)
NL (1) NL7017428A (en)
ZA (1) ZA717307B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3909770A1 (en) * 1989-03-21 1990-09-27 Schering Ag METHOD FOR PRODUCING 3-DESOXY-4-EN STEROIDS

Also Published As

Publication number Publication date
BE775052A (en) 1972-03-01
ZA717307B (en) 1972-07-26
AU3545671A (en) 1973-05-17
NL7017428A (en) 1972-05-30
ES397385A1 (en) 1974-05-16
DE2158837A1 (en) 1972-05-31

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Legal Events

Date Code Title Description
ST Notification of lapse