FR2106463A1 - Prostaglandins e2, fe alpha and f2 beta - and analogues from derivs extracted from plexaura homomalla - Google Patents
Prostaglandins e2, fe alpha and f2 beta - and analogues from derivs extracted from plexaura homomallaInfo
- Publication number
- FR2106463A1 FR2106463A1 FR7132823A FR7132823A FR2106463A1 FR 2106463 A1 FR2106463 A1 FR 2106463A1 FR 7132823 A FR7132823 A FR 7132823A FR 7132823 A FR7132823 A FR 7132823A FR 2106463 A1 FR2106463 A1 FR 2106463A1
- Authority
- FR
- France
- Prior art keywords
- beta
- alpha
- acetate methyl
- pgf2
- methyl ester
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 241000219210 Plexaura homomalla Species 0.000 title 1
- 229940094443 oxytocics prostaglandins Drugs 0.000 title 1
- 150000003180 prostaglandins Chemical class 0.000 title 1
- PXGPLTODNUVGFL-CKXCCYAOSA-N 15R-PGF2alpha Chemical compound CCCCC[C@@H](O)\C=C\[C@H]1[C@H](O)C[C@H](O)[C@@H]1C\C=C/CCCC(O)=O PXGPLTODNUVGFL-CKXCCYAOSA-N 0.000 abstract 4
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 abstract 4
- 229960002986 dinoprostone Drugs 0.000 abstract 4
- LOLJEILMPWPILA-AMFHKTBMSA-N 15-oxoprostaglandin F2alpha Chemical compound CCCCCC(=O)\C=C\[C@H]1[C@H](O)C[C@H](O)[C@@H]1C\C=C/CCCC(O)=O LOLJEILMPWPILA-AMFHKTBMSA-N 0.000 abstract 3
- 239000000203 mixture Substances 0.000 abstract 3
- 229910008338 Si—(CH3) Inorganic materials 0.000 abstract 2
- 150000002118 epoxides Chemical class 0.000 abstract 2
- 230000003301 hydrolyzing effect Effects 0.000 abstract 2
- KXKVLQRXCPHEJC-UHFFFAOYSA-N methyl acetate Chemical compound COC(C)=O KXKVLQRXCPHEJC-UHFFFAOYSA-N 0.000 abstract 2
- PXGPLTODNUVGFL-BRIYLRKRSA-N (E,Z)-(1R,2R,3R,5S)-7-(3,5-Dihydroxy-2-((3S)-(3-hydroxy-1-octenyl))cyclopentyl)-5-heptenoic acid Chemical compound CCCCC[C@H](O)C=C[C@H]1[C@H](O)C[C@H](O)[C@@H]1CC=CCCCC(O)=O PXGPLTODNUVGFL-BRIYLRKRSA-N 0.000 abstract 1
- 229910007161 Si(CH3)3 Inorganic materials 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/38—Compounds containing oxirane rings with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D303/40—Compounds containing oxirane rings with hydrocarbon radicals, substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals by ester radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US7139070A | 1970-09-11 | 1970-09-11 | |
| US7139670A | 1970-09-11 | 1970-09-11 | |
| US15946971A | 1971-07-02 | 1971-07-02 | |
| US15948971A | 1971-07-02 | 1971-07-02 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2106463A1 true FR2106463A1 (en) | 1972-05-05 |
| FR2106463B1 FR2106463B1 (fr) | 1978-08-18 |
Family
ID=27490895
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7132823A Granted FR2106463A1 (en) | 1970-09-11 | 1971-09-10 | Prostaglandins e2, fe alpha and f2 beta - and analogues from derivs extracted from plexaura homomalla |
| FR7529267A Granted FR2279730A1 (fr) | 1970-09-11 | 1975-09-24 | Derives 10,11 epoxy de prostaglandines et leurs procedes de preparation |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7529267A Granted FR2279730A1 (fr) | 1970-09-11 | 1975-09-24 | Derives 10,11 epoxy de prostaglandines et leurs procedes de preparation |
Country Status (5)
| Country | Link |
|---|---|
| CH (1) | CH572468A5 (fr) |
| DE (3) | DE2166721A1 (fr) |
| FR (2) | FR2106463A1 (fr) |
| NL (1) | NL7112462A (fr) |
| SE (2) | SE391714B (fr) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2166194A1 (fr) * | 1971-12-30 | 1973-08-10 | Upjohn Co | |
| FR2209739A1 (en) * | 1972-12-13 | 1974-07-05 | Aries Robert | Separating mixtures of prostanoic acid derivs - by passage through non ionic resins, eluting with aqueous alcohols |
| FR2219146A1 (en) * | 1973-02-28 | 1974-09-20 | Aries Robert | Prepn. of prostaglandins - from prostaglandin A2 by reduction and hydroxylation |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3887587A (en) * | 1972-04-17 | 1975-06-03 | Pfizer | Synthesis of prostaglandins of the one-series |
| SE8703854D0 (sv) * | 1987-10-07 | 1987-10-07 | Pharmacia Ab | Prostaglandinderivat for behandling av glaukom eller okuler hypertension |
-
1971
- 1971-09-09 SE SE7111423A patent/SE391714B/xx unknown
- 1971-09-09 DE DE19712166721 patent/DE2166721A1/de active Pending
- 1971-09-09 DE DE19712166720 patent/DE2166720A1/de active Pending
- 1971-09-09 DE DE19712145125 patent/DE2145125A1/de active Pending
- 1971-09-10 NL NL7112462A patent/NL7112462A/xx unknown
- 1971-09-10 CH CH1335371A patent/CH572468A5/xx not_active IP Right Cessation
- 1971-09-10 FR FR7132823A patent/FR2106463A1/fr active Granted
-
1974
- 1974-09-13 SE SE7411566A patent/SE7411566L/xx unknown
-
1975
- 1975-09-24 FR FR7529267A patent/FR2279730A1/fr active Granted
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2166194A1 (fr) * | 1971-12-30 | 1973-08-10 | Upjohn Co | |
| FR2209739A1 (en) * | 1972-12-13 | 1974-07-05 | Aries Robert | Separating mixtures of prostanoic acid derivs - by passage through non ionic resins, eluting with aqueous alcohols |
| FR2219146A1 (en) * | 1973-02-28 | 1974-09-20 | Aries Robert | Prepn. of prostaglandins - from prostaglandin A2 by reduction and hydroxylation |
Also Published As
| Publication number | Publication date |
|---|---|
| DE2166721A1 (de) | 1975-05-15 |
| SE391714B (sv) | 1977-02-28 |
| CH572468A5 (fr) | 1976-02-13 |
| DE2145125A1 (de) | 1972-04-06 |
| FR2279730A1 (fr) | 1976-02-20 |
| DE2166720A1 (de) | 1975-08-28 |
| NL7112462A (fr) | 1972-03-14 |
| FR2279730B1 (fr) | 1979-02-02 |
| SE7411566L (fr) | 1974-09-13 |
| FR2106463B1 (fr) | 1978-08-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |