FR2100850A1 - 4-hydroxy isophthalic acid 3-picolyl amides - with anticoagulant and fibrinolytic activity - Google Patents

4-hydroxy isophthalic acid 3-picolyl amides - with anticoagulant and fibrinolytic activity

Info

Publication number
FR2100850A1
FR2100850A1 FR7123901A FR7123901A FR2100850A1 FR 2100850 A1 FR2100850 A1 FR 2100850A1 FR 7123901 A FR7123901 A FR 7123901A FR 7123901 A FR7123901 A FR 7123901A FR 2100850 A1 FR2100850 A1 FR 2100850A1
Authority
FR
France
Prior art keywords
isophthalic acid
anticoagulant
fibrinolytic activity
hydroxy isophthalic
picolyl amides
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7123901A
Other languages
English (en)
French (fr)
Other versions
FR2100850B1 (enExample
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Manetti & Roberts Italo Brit
Original Assignee
Manetti & Roberts Italo Brit
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Manetti & Roberts Italo Brit filed Critical Manetti & Roberts Italo Brit
Publication of FR2100850A1 publication Critical patent/FR2100850A1/fr
Application granted granted Critical
Publication of FR2100850B1 publication Critical patent/FR2100850B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/36—Radicals substituted by singly-bound nitrogen atoms
    • C07D213/40—Acylated substituent nitrogen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pyridine Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR7123901A 1970-07-01 1971-06-30 4-hydroxy isophthalic acid 3-picolyl amides - with anticoagulant and fibrinolytic activity Granted FR2100850A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT5181270A IT1016005B (it) 1970-07-01 1970-07-01 Picolilamidi dell acido 4 idrossi isoftalico e suoi derivati e relativo procedimento di prepara zione

Publications (2)

Publication Number Publication Date
FR2100850A1 true FR2100850A1 (en) 1972-03-24
FR2100850B1 FR2100850B1 (enExample) 1975-10-10

Family

ID=11275776

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7123901A Granted FR2100850A1 (en) 1970-07-01 1971-06-30 4-hydroxy isophthalic acid 3-picolyl amides - with anticoagulant and fibrinolytic activity

Country Status (3)

Country Link
BE (1) BE851967Q (enExample)
FR (1) FR2100850A1 (enExample)
IT (1) IT1016005B (enExample)

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2300566A1 (fr) * 1975-02-11 1976-09-10 Manetti & Roberts Italo Brit Inhibiteur d'agregation des plaquettes sanguines et procede pour sa preparation
FR2401922A1 (fr) * 1977-09-06 1979-03-30 Manetti & Roberts Italo Brit Picolylamides d'acides 4-hydroxy-isophtaliques substitues, leur preparation et leurs utilisations therapeutiques
FR2481283A1 (enExample) * 1980-04-23 1981-10-30 Manetti & Roberts Italo Brit
US4698354A (en) * 1985-10-10 1987-10-06 Societa Italo-Brittanica L. Manetti-H. Roberts & Co. 4-methoxy-isophthalic acid derivative having a pharmacological activity in thromboembolic disorders
EP0530444A1 (en) * 1991-08-01 1993-03-10 American Cyanamid Company Aryl, amide, imide, and carbamate pyridine antagonists of platelet activating factor
WO2008142106A1 (en) * 2007-05-21 2008-11-27 Dybly Ag Salts of picotamide
CN103664804A (zh) * 2013-11-12 2014-03-26 安徽中医药大学 吡考他胺类似物、制备方法及其应用
CN112159347B (zh) * 2020-10-27 2022-06-07 常州工程职业技术学院 吡考他胺的制备方法

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3367940A (en) * 1963-01-02 1968-02-06 Chevron Res Beta-picolinamide derivatives

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3367940A (en) * 1963-01-02 1968-02-06 Chevron Res Beta-picolinamide derivatives

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2300566A1 (fr) * 1975-02-11 1976-09-10 Manetti & Roberts Italo Brit Inhibiteur d'agregation des plaquettes sanguines et procede pour sa preparation
FR2401922A1 (fr) * 1977-09-06 1979-03-30 Manetti & Roberts Italo Brit Picolylamides d'acides 4-hydroxy-isophtaliques substitues, leur preparation et leurs utilisations therapeutiques
FR2481283A1 (enExample) * 1980-04-23 1981-10-30 Manetti & Roberts Italo Brit
DK155735B (da) * 1980-04-23 1989-05-08 Sandoz Ag Fremgangsmaade til fremstilling af monohydratiseret n,n'-bis-(3-picolyl)-4-methoxy-isophthalamid
US4698354A (en) * 1985-10-10 1987-10-06 Societa Italo-Brittanica L. Manetti-H. Roberts & Co. 4-methoxy-isophthalic acid derivative having a pharmacological activity in thromboembolic disorders
EP0530444A1 (en) * 1991-08-01 1993-03-10 American Cyanamid Company Aryl, amide, imide, and carbamate pyridine antagonists of platelet activating factor
WO2008142106A1 (en) * 2007-05-21 2008-11-27 Dybly Ag Salts of picotamide
CN103664804A (zh) * 2013-11-12 2014-03-26 安徽中医药大学 吡考他胺类似物、制备方法及其应用
CN103664804B (zh) * 2013-11-12 2016-01-20 安徽中医药大学 吡考他胺类似物、制备方法及其应用
CN112159347B (zh) * 2020-10-27 2022-06-07 常州工程职业技术学院 吡考他胺的制备方法

Also Published As

Publication number Publication date
BE851967Q (fr) 1977-07-01
IT1016005B (it) 1977-05-30
FR2100850B1 (enExample) 1975-10-10

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