FR2081417A1 - Anti-androgenic 16 beta-hydrocarbyl-oest- - rane derivs - Google Patents
Anti-androgenic 16 beta-hydrocarbyl-oest- - rane derivsInfo
- Publication number
- FR2081417A1 FR2081417A1 FR7100263A FR7100263A FR2081417A1 FR 2081417 A1 FR2081417 A1 FR 2081417A1 FR 7100263 A FR7100263 A FR 7100263A FR 7100263 A FR7100263 A FR 7100263A FR 2081417 A1 FR2081417 A1 FR 2081417A1
- Authority
- FR
- France
- Prior art keywords
- hydrocarbyl
- derivs
- androgenic
- beta
- oest
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J75/00—Processes for the preparation of steroids in general
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Anti-androgenic 16 beta-hydrocarbyl-oestrane derivs. Title cpds. of formula (I) (where A is H or acyl and R is 2C hydrocarbyl), which are useful in the treatment of prostate adenoma, are prepd. by hydrolysing a cpd. of formula (II) or (III) (where R' is acyl or hydrocarbyl) and opt. acylating a resulting cpd. in which-A is n or further hydrolysing a product in which A is acyl.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP238570A JPS4916856B1 (en) | 1970-01-07 | 1970-01-07 | |
JP5748570A JPS4916858B1 (en) | 1970-07-01 | 1970-07-01 |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2081417A1 true FR2081417A1 (en) | 1971-12-03 |
FR2081417B1 FR2081417B1 (en) | 1975-04-18 |
Family
ID=26335748
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7100263A Granted FR2081417A1 (en) | 1970-01-07 | 1971-01-06 | Anti-androgenic 16 beta-hydrocarbyl-oest- - rane derivs |
Country Status (11)
Country | Link |
---|---|
CA (1) | CA945140A (en) |
CH (1) | CH577527A5 (en) |
DE (1) | DE2100319C3 (en) |
DK (1) | DK129123B (en) |
FR (1) | FR2081417A1 (en) |
HK (1) | HK1877A (en) |
HU (1) | HU163056B (en) |
MY (1) | MY7700131A (en) |
NL (1) | NL151006B (en) |
SE (1) | SE366031B (en) |
SU (1) | SU482041A3 (en) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3027908A1 (en) * | 1980-07-21 | 1982-03-18 | Schering Ag, 1000 Berlin Und 4619 Bergkamen | 16 (BETA) -ETHYLSTEROIDS, PREPARATIONS CONTAINING THE SAME AND METHOD FOR THE PRODUCTION THEREOF |
GR77885B (en) * | 1982-03-20 | 1984-09-25 | Wakon Tsuchiya |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR1453828A (en) * | 1964-02-29 | 1966-09-30 | Organon Nv | Novel 16-alkyl-steroids and process for their preparation |
-
1971
- 1971-01-05 SU SU1607737A patent/SU482041A3/en active
- 1971-01-05 DE DE19712100319 patent/DE2100319C3/en not_active Expired
- 1971-01-05 SE SE6071A patent/SE366031B/xx unknown
- 1971-01-06 NL NL7100131A patent/NL151006B/en not_active IP Right Cessation
- 1971-01-06 FR FR7100263A patent/FR2081417A1/en active Granted
- 1971-01-06 DK DK3371A patent/DK129123B/en not_active IP Right Cessation
- 1971-01-07 HU HUTA001100 patent/HU163056B/hu unknown
- 1971-01-07 CA CA102,163A patent/CA945140A/en not_active Expired
- 1971-01-07 CH CH20871A patent/CH577527A5/xx not_active IP Right Cessation
-
1977
- 1977-01-13 HK HK1877A patent/HK1877A/en unknown
- 1977-12-30 MY MY7700131A patent/MY7700131A/en unknown
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR1453828A (en) * | 1964-02-29 | 1966-09-30 | Organon Nv | Novel 16-alkyl-steroids and process for their preparation |
Also Published As
Publication number | Publication date |
---|---|
NL7100131A (en) | 1971-07-09 |
FR2081417B1 (en) | 1975-04-18 |
DE2100319C3 (en) | 1974-10-31 |
HU163056B (en) | 1973-05-28 |
NL151006B (en) | 1976-10-15 |
SU482041A3 (en) | 1975-08-25 |
DK129123B (en) | 1974-08-26 |
HK1877A (en) | 1977-01-21 |
DE2100319A1 (en) | 1971-07-15 |
CH577527A5 (en) | 1976-07-15 |
SE366031B (en) | 1974-04-08 |
DE2100319B2 (en) | 1974-03-28 |
MY7700131A (en) | 1977-12-31 |
DK129123C (en) | 1975-01-20 |
CA945140A (en) | 1974-04-09 |
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