FR2081426A1 - Spasmolytic dihydrobenz-1,4-oxazepine deriv - Google Patents
Spasmolytic dihydrobenz-1,4-oxazepine derivInfo
- Publication number
- FR2081426A1 FR2081426A1 FR7100812A FR7100812A FR2081426A1 FR 2081426 A1 FR2081426 A1 FR 2081426A1 FR 7100812 A FR7100812 A FR 7100812A FR 7100812 A FR7100812 A FR 7100812A FR 2081426 A1 FR2081426 A1 FR 2081426A1
- Authority
- FR
- France
- Prior art keywords
- substd
- alkyl
- dihydrobenz
- oxazepine
- deriv
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 230000002048 spasmolytic effect Effects 0.000 title abstract 2
- 239000000812 cholinergic antagonist Substances 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- XHXFXVLFKHQFAL-UHFFFAOYSA-N phosphoryl trichloride Chemical compound ClP(Cl)(Cl)=O XHXFXVLFKHQFAL-UHFFFAOYSA-N 0.000 abstract 2
- 125000006273 (C1-C3) alkyl group Chemical group 0.000 abstract 1
- PUAQLLVFLMYYJJ-UHFFFAOYSA-N 2-aminopropiophenone Chemical compound CC(N)C(=O)C1=CC=CC=C1 PUAQLLVFLMYYJJ-UHFFFAOYSA-N 0.000 abstract 1
- -1 PCL3 Chemical compound 0.000 abstract 1
- 229910019213 POCl3 Inorganic materials 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000006193 alkinyl group Chemical group 0.000 abstract 1
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- 125000004104 aryloxy group Chemical group 0.000 abstract 1
- 125000002619 bicyclic group Chemical group 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 125000004122 cyclic group Chemical group 0.000 abstract 1
- 125000002950 monocyclic group Chemical group 0.000 abstract 1
- 229940035363 muscle relaxants Drugs 0.000 abstract 1
- 239000003158 myorelaxant agent Substances 0.000 abstract 1
- UHZYTMXLRWXGPK-UHFFFAOYSA-N phosphorus pentachloride Chemical compound ClP(Cl)(Cl)(Cl)Cl UHZYTMXLRWXGPK-UHFFFAOYSA-N 0.000 abstract 1
- 125000004076 pyridyl group Chemical group 0.000 abstract 1
- 125000000714 pyrimidinyl group Chemical group 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D267/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D267/02—Seven-membered rings
- C07D267/08—Seven-membered rings having the hetero atoms in positions 1 and 4
- C07D267/12—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D267/14—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with one six-membered ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
LU60171 | 1970-01-12 | ||
LU62353 | 1970-12-31 |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2081426A1 true FR2081426A1 (en) | 1971-12-03 |
FR2081426B1 FR2081426B1 (enrdf_load_stackoverflow) | 1975-04-18 |
Family
ID=26640047
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR7100812A Granted FR2081426A1 (en) | 1970-01-12 | 1971-01-12 | Spasmolytic dihydrobenz-1,4-oxazepine deriv |
Country Status (4)
Country | Link |
---|---|
BE (1) | BE761315A (enrdf_load_stackoverflow) |
DE (1) | DE2100654A1 (enrdf_load_stackoverflow) |
FR (1) | FR2081426A1 (enrdf_load_stackoverflow) |
NL (1) | NL7100335A (enrdf_load_stackoverflow) |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2730489A1 (fr) * | 1995-02-09 | 1996-08-14 | Egyt Gyogyszervegyeszeti Gyar | Derives de 1-(2-(vinyl-substitues))-5h-2,3-benzodiazepine |
EP0726257A1 (en) * | 1995-02-09 | 1996-08-14 | Egis Gyogyszergyar Rt. | 1-(Hetero)Arylvinyl-5H-2,3-benzodiazepine derivatives useful for the treatment of central nervous system disorders, and benzopyrylium intermediates for their preparation |
FR2730490A1 (fr) * | 1995-02-09 | 1996-08-14 | Egyt Gyogyszervegyeszeti Gyar | Derives 1-(2-(vinyl-substitues))-3,4-dihydro-5h-2,3- benzodiazepine |
ES2111493A1 (es) * | 1996-02-08 | 1998-03-01 | Egyt Gyogyszervegyeszeti Gyar | Derivados de 1-(2- (vinilo substituido ) ) -5h-2,3-benzo-diazepina, procedimiento para su preparacion, composiciones farmaceuticas que los contienen y utilizaciones correspondientes. |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4125538A (en) | 1977-02-04 | 1978-11-14 | Bristol-Myers Company | Substituted 5-phenyl-2,3,4,5-tetrahydro-1,4-benzoxazepines |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BE695313A (enrdf_load_stackoverflow) * | 1966-03-10 | 1967-09-11 | ||
CH481128A (de) * | 1967-04-26 | 1969-11-15 | Geigy Ag J R | Verfahren zur Herstellung von neuen Oxazepinen |
-
1971
- 1971-01-07 BE BE761315A patent/BE761315A/xx unknown
- 1971-01-08 DE DE19712100654 patent/DE2100654A1/de active Pending
- 1971-01-11 NL NL7100335A patent/NL7100335A/xx unknown
- 1971-01-12 FR FR7100812A patent/FR2081426A1/fr active Granted
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BE695313A (enrdf_load_stackoverflow) * | 1966-03-10 | 1967-09-11 | ||
CH481128A (de) * | 1967-04-26 | 1969-11-15 | Geigy Ag J R | Verfahren zur Herstellung von neuen Oxazepinen |
Cited By (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2730489A1 (fr) * | 1995-02-09 | 1996-08-14 | Egyt Gyogyszervegyeszeti Gyar | Derives de 1-(2-(vinyl-substitues))-5h-2,3-benzodiazepine |
EP0726257A1 (en) * | 1995-02-09 | 1996-08-14 | Egis Gyogyszergyar Rt. | 1-(Hetero)Arylvinyl-5H-2,3-benzodiazepine derivatives useful for the treatment of central nervous system disorders, and benzopyrylium intermediates for their preparation |
EP0726256A1 (en) * | 1995-02-09 | 1996-08-14 | Egis Gyogyszergyar Rt. | 1-Arylvinyl-3,4-dihydro-5H-2,3-benzodiazepine derivatives useful for the treatment of central nervous system disorders |
FR2730490A1 (fr) * | 1995-02-09 | 1996-08-14 | Egyt Gyogyszervegyeszeti Gyar | Derives 1-(2-(vinyl-substitues))-3,4-dihydro-5h-2,3- benzodiazepine |
BE1009516A3 (fr) * | 1995-02-09 | 1997-04-01 | Egyt Gyogyszervegyeszeti Gyar | Derives de 1-[2-(vinyl-substitues)]-5h-2,3-benzodiazepine. |
BE1009852A3 (fr) * | 1995-02-09 | 1997-10-07 | Egyt Gyogyszervegyeszeti Gyar | Derives 1-[2(vinyl-substitues)]-3-4-dihydro-5h-2,3-benzodiazepine. |
ES2111492A1 (es) * | 1995-02-09 | 1998-03-01 | Egyt Gyogyszervegyeszeti Gyar | Derivados de 1-(2-(vinilo substituido))-3,4-dihidro-5h-2,3-benzodiazepina, procedimiento para su preparacion, composiciones farmaceuticas que los contienen y utilizacion de dichos derivados y composiciones para el tratamiento de trastornos del sistema nervioso central. |
ES2111493A1 (es) * | 1996-02-08 | 1998-03-01 | Egyt Gyogyszervegyeszeti Gyar | Derivados de 1-(2- (vinilo substituido ) ) -5h-2,3-benzo-diazepina, procedimiento para su preparacion, composiciones farmaceuticas que los contienen y utilizaciones correspondientes. |
Also Published As
Publication number | Publication date |
---|---|
BE761315A (enrdf_load_stackoverflow) | 1971-07-07 |
FR2081426B1 (enrdf_load_stackoverflow) | 1975-04-18 |
DE2100654A1 (de) | 1971-07-22 |
NL7100335A (enrdf_load_stackoverflow) | 1971-07-14 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
ST | Notification of lapse |