FR2035903A1 - Alpha-alkyl, alpha-(para-(1,2,3,4-tetrahydro - -1-naphthyl) pehnoxy) acetic acids hypolipae - Google Patents

Alpha-alkyl, alpha-(para-(1,2,3,4-tetrahydro - -1-naphthyl) pehnoxy) acetic acids hypolipae

Info

Publication number
FR2035903A1
FR2035903A1 FR7010713A FR7010713A FR2035903A1 FR 2035903 A1 FR2035903 A1 FR 2035903A1 FR 7010713 A FR7010713 A FR 7010713A FR 7010713 A FR7010713 A FR 7010713A FR 2035903 A1 FR2035903 A1 FR 2035903A1
Authority
FR
France
Prior art keywords
alpha
alkyl
tetrahydro
para
naphthyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
FR7010713A
Other languages
French (fr)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
JR Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by JR Geigy AG filed Critical JR Geigy AG
Publication of FR2035903A1 publication Critical patent/FR2035903A1/en
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
    • C07C59/66—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
    • C07C59/66—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings
    • C07C59/68—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings the oxygen atom of the ether group being bound to a non-condensed six-membered aromatic ring
    • C07C59/70—Ethers of hydroxy-acetic acid, e.g. substitutes on the ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Alpha-alkyl, alpha- para-(1,2,3,4-tetrahydro-1-naphthyl)-phenoxy acetic acids; hypolipaemics. Compds. of formula (I): (wherein R = 3-10C alkyl or PhCH2), and their salts with alk. metals and alk. earth metals, useful as hypolipaemic agents, are prepd. by etherifying a tetrahydronaphthyl phenol with an alpha-hydroxy carboxylic acid deriv. or by decarboxylating a subst. malonic acid or ester or by hydrolysing a functional deriv. of the title compd.
FR7010713A 1969-03-26 1970-03-25 Alpha-alkyl, alpha-(para-(1,2,3,4-tetrahydro - -1-naphthyl) pehnoxy) acetic acids hypolipae Withdrawn FR2035903A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH456769 1969-03-26

Publications (1)

Publication Number Publication Date
FR2035903A1 true FR2035903A1 (en) 1970-12-24

Family

ID=4278487

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7010713A Withdrawn FR2035903A1 (en) 1969-03-26 1970-03-25 Alpha-alkyl, alpha-(para-(1,2,3,4-tetrahydro - -1-naphthyl) pehnoxy) acetic acids hypolipae

Country Status (8)

Country Link
BE (1) BE747947A (en)
BR (1) BR7017763D0 (en)
CH (3) CH505046A (en)
DE (1) DE2014479A1 (en)
FR (1) FR2035903A1 (en)
IL (1) IL34157A0 (en)
NL (1) NL7003945A (en)
ZA (1) ZA702057B (en)

Also Published As

Publication number Publication date
CH505047A (en) 1971-03-31
ZA702057B (en) 1971-01-27
IL34157A0 (en) 1970-05-21
CH505046A (en) 1971-03-31
BR7017763D0 (en) 1973-02-13
DE2014479A1 (en) 1970-10-08
NL7003945A (en) 1970-09-29
BE747947A (en) 1970-09-25
CH505048A (en) 1971-03-31

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Legal Events

Date Code Title Description
ST Notification of lapse