GB1127868A - The preparation of c alkyl esters of ª‡-methyl-ª‡-cyano-ªß-(3,4-disubstituted phenyl)propionic acids - Google Patents

The preparation of c alkyl esters of ª‡-methyl-ª‡-cyano-ªß-(3,4-disubstituted phenyl)propionic acids

Info

Publication number
GB1127868A
GB1127868A GB4680266A GB4680266A GB1127868A GB 1127868 A GB1127868 A GB 1127868A GB 4680266 A GB4680266 A GB 4680266A GB 4680266 A GB4680266 A GB 4680266A GB 1127868 A GB1127868 A GB 1127868A
Authority
GB
United Kingdom
Prior art keywords
cyano
methyl
preparation
alkyl esters
disubstituted phenyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB4680266A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of GB1127868A publication Critical patent/GB1127868A/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

1,127,868. Esters of substituted 2-benzyl-2- cyanopropionic acids. MERCK & CO. Inc. 19 Oct., 1966 [22 Oct., 1965], No. 46802/66. Heading C2C. The racemic form of a compound of formula wherein R 1 and R 2 are each H or C 1-4 alkyl, R 3 is C 1-8 alkyl and n is 0 or 1, is obtained by resolving the corresponding acid (R 3 =H), recovering the D and L forms separately as the esters, contacting the D-ester with an aqueous solution of a strong acid to form the corresponding D-2-carbamyl ester, racemizing the latter and dehydrating the product.
GB4680266A 1965-10-22 1966-10-19 The preparation of c alkyl esters of ª‡-methyl-ª‡-cyano-ªß-(3,4-disubstituted phenyl)propionic acids Expired GB1127868A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US50235565A 1965-10-22 1965-10-22

Publications (1)

Publication Number Publication Date
GB1127868A true GB1127868A (en) 1968-09-18

Family

ID=23997440

Family Applications (1)

Application Number Title Priority Date Filing Date
GB4680266A Expired GB1127868A (en) 1965-10-22 1966-10-19 The preparation of c alkyl esters of ª‡-methyl-ª‡-cyano-ªß-(3,4-disubstituted phenyl)propionic acids

Country Status (6)

Country Link
BR (1) BR6683809D0 (en)
CH (1) CH484877A (en)
DE (1) DE1543774A1 (en)
FR (1) FR1502950A (en)
GB (1) GB1127868A (en)
NL (1) NL6614972A (en)

Also Published As

Publication number Publication date
FR1502950A (en) 1967-11-24
NL6614972A (en) 1967-04-24
DE1543774A1 (en) 1970-02-12
CH484877A (en) 1970-01-31
BR6683809D0 (en) 1973-12-04

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