FR2015812A1 - Analgesic hexahydro 1h azepine derivs - Google Patents
Analgesic hexahydro 1h azepine derivsInfo
- Publication number
- FR2015812A1 FR2015812A1 FR6928129A FR6928129A FR2015812A1 FR 2015812 A1 FR2015812 A1 FR 2015812A1 FR 6928129 A FR6928129 A FR 6928129A FR 6928129 A FR6928129 A FR 6928129A FR 2015812 A1 FR2015812 A1 FR 2015812A1
- Authority
- FR
- France
- Prior art keywords
- analgesic
- alkyl
- derivs
- hexahydro
- azepine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 230000000202 analgesic effect Effects 0.000 title abstract 4
- ZSIQJIWKELUFRJ-UHFFFAOYSA-N azepane Chemical compound C1CCCNCC1 ZSIQJIWKELUFRJ-UHFFFAOYSA-N 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 4
- 125000001589 carboacyl group Chemical group 0.000 abstract 2
- PUAQLLVFLMYYJJ-UHFFFAOYSA-N 2-aminopropiophenone Chemical compound CC(N)C(=O)C1=CC=CC=C1 PUAQLLVFLMYYJJ-UHFFFAOYSA-N 0.000 abstract 1
- 125000000094 2-phenylethyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])* 0.000 abstract 1
- XAKBSHICSHRJCL-UHFFFAOYSA-N [CH2]C(=O)C1=CC=CC=C1 Chemical group [CH2]C(=O)C1=CC=CC=C1 XAKBSHICSHRJCL-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000000304 alkynyl group Chemical group 0.000 abstract 1
- 150000003863 ammonium salts Chemical class 0.000 abstract 1
- 239000005557 antagonist Substances 0.000 abstract 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
- -1 beta-benzoylethyl Chemical group 0.000 abstract 1
- 125000004186 cyclopropylmethyl group Chemical group [H]C([H])(*)C1([H])C([H])([H])C1([H])[H] 0.000 abstract 1
- 125000002485 formyl group Chemical group [H]C(*)=O 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/02—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D223/04—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings with only hydrogen atoms, halogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB3920168 | 1968-08-16 | ||
| GB4206068 | 1968-09-04 | ||
| GB4694/69A GB1285025A (en) | 1968-08-16 | 1969-01-28 | Hexahydroazepines |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| FR2015812A1 true FR2015812A1 (en) | 1970-04-30 |
Family
ID=27254483
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR6928129A Withdrawn FR2015812A1 (en) | 1968-08-16 | 1969-08-14 | Analgesic hexahydro 1h azepine derivs |
Country Status (18)
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1319785A (en) * | 1970-02-06 | 1973-06-06 | Wyeth John & Brother Ltd | Hexahydroazepines |
| US3666752A (en) * | 1970-03-09 | 1972-05-30 | Bristol Myers Co | 4,4-diphenylhexahydroazepine compounds |
| DE2901180A1 (de) * | 1979-01-13 | 1980-07-24 | Basf Ag | Hexahydro-1,4-oxazepine, verfahren zu deren herstellung und diese enthaltende arzneimittel |
| SE439186B (sv) * | 1980-12-04 | 1985-06-03 | Olof Ohrnell | Elastisk koppling mellan ett inre och ett yttre i forhallande till varandra koncentriska ror |
| DE3502667A1 (de) * | 1985-01-26 | 1986-07-31 | Klöckner-Humboldt-Deutz AG, 5000 Köln | Oelschleuderfilter fuer brennkraftmaschinen |
| EP1679069A4 (en) * | 2003-10-21 | 2009-05-13 | Dainippon Sumitomo Pharma Co | NEW PIPERIDINE DERIVATIVE |
| US20190031615A1 (en) * | 2016-01-15 | 2019-01-31 | Laboratorios Del Dr. Esteve S.A. | 3-ethyl-3-phenylazepane derivatives having multimodal activity against pain |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2740779A (en) * | 1956-04-03 | Substituted azacycloalkanes |
-
1969
- 1969-08-06 IE IE1102/69A patent/IE33382B1/xx unknown
- 1969-08-08 IL IL32801A patent/IL32801A/xx unknown
- 1969-08-14 DE DE1941534A patent/DE1941534C3/de not_active Expired
- 1969-08-14 IT IT20967/69A patent/IT1053698B/it active
- 1969-08-14 ES ES370497A patent/ES370497A1/es not_active Expired
- 1969-08-14 FR FR6928129A patent/FR2015812A1/fr not_active Withdrawn
- 1969-08-14 BE BE737548D patent/BE737548A/xx not_active IP Right Cessation
- 1969-08-15 NL NL6912483.A patent/NL164275C/xx not_active IP Right Cessation
- 1969-08-15 SE SE11395/69A patent/SE366043B/xx unknown
- 1969-08-15 CH CH1241969A patent/CH536843A/de not_active IP Right Cessation
- 1969-08-15 YU YU2102/69A patent/YU34124B/xx unknown
- 1969-08-15 HU HUWI160A patent/HU162512B/hu unknown
- 1969-08-15 NO NO3311/69A patent/NO132046C/no unknown
- 1969-08-15 DK DK439969AA patent/DK141401B/da not_active IP Right Cessation
- 1969-08-15 CH CH1056472A patent/CH554864A/xx not_active IP Right Cessation
- 1969-08-15 CH CH340773A patent/CH554865A/xx not_active IP Right Cessation
- 1969-08-15 JP JP44064669A patent/JPS505197B1/ja active Pending
- 1969-08-15 FI FI692393A patent/FI51479C/fi active
- 1969-08-18 AT AT789269A patent/AT312611B/de not_active IP Right Cessation
-
1971
- 1971-07-09 DK DK340571A patent/DK150849C/da not_active IP Right Cessation
- 1971-11-30 AR AR239343A patent/AR194353A1/es active
-
1975
- 1975-02-11 NO NO750442A patent/NO142395C/no unknown
- 1975-10-27 YU YU02716/75A patent/YU39170B/xx unknown
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2740779A (en) * | 1956-04-03 | Substituted azacycloalkanes |
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |