FR1460659A - Nouveaux acides biphényl-acétiques substitués et procédés pour leur préparation - Google Patents

Nouveaux acides biphényl-acétiques substitués et procédés pour leur préparation

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Publication number
FR1460659A
FR1460659A FR30712A FR30712A FR1460659A FR 1460659 A FR1460659 A FR 1460659A FR 30712 A FR30712 A FR 30712A FR 30712 A FR30712 A FR 30712A FR 1460659 A FR1460659 A FR 1460659A
Authority
FR
France
Prior art keywords
processes
preparation
acetic acids
substituted biphenyl
new substituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR30712A
Other languages
English (en)
French (fr)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Priority to FR30712A priority Critical patent/FR1460659A/fr
Priority to FR41105A priority patent/FR7047M/fr
Application granted granted Critical
Publication of FR1460659A publication Critical patent/FR1460659A/fr
Priority to FR121826A priority patent/FR7008M/fr
Priority to FR121824A priority patent/FR7007M/fr
Priority to FR121825A priority patent/FR7048M/fr
Expired legal-status Critical Current

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/06Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C201/00Preparation of esters of nitric or nitrous acid or of compounds containing nitro or nitroso groups bound to a carbon skeleton
    • C07C201/06Preparation of nitro compounds
    • C07C201/12Preparation of nitro compounds by reactions not involving the formation of nitro groups
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    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/45Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by at least one doubly—bound oxygen atom, not being part of a —CHO group
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    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/49Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups
    • C07C205/56Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups bound to carbon atoms of six-membered aromatic rings and carboxyl groups bound to acyclic carbon atoms of the carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/49Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups
    • C07C205/57Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
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    • C07C227/00Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/04Formation of amino groups in compounds containing carboxyl groups
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    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/52Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton
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    • C07C231/00Preparation of carboxylic acid amides
    • C07C231/02Preparation of carboxylic acid amides from carboxylic acids or from esters, anhydrides, or halides thereof by reaction with ammonia or amines
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    • C07C253/00Preparation of carboxylic acid nitriles
    • C07C253/30Preparation of carboxylic acid nitriles by reactions not involving the formation of cyano groups
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    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C303/00Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides
    • C07C303/02Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of sulfonic acids or halides thereof
    • C07C303/16Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of sulfonic acids or halides thereof by oxidation of thiols, sulfides, hydropolysulfides, or polysulfides with formation of sulfo or halosulfonyl groups
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    • C07C303/00Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides
    • C07C303/36Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of amides of sulfonic acids
    • C07C303/38Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of amides of sulfonic acids by reaction of ammonia or amines with sulfonic acids, or with esters, anhydrides, or halides thereof
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    • C07C315/00Preparation of sulfones; Preparation of sulfoxides
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    • C07C323/50Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/62Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton
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    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
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    • C07C45/46Friedel-Crafts reactions
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    • C07C45/63Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by introduction of halogen; by substitution of halogen atoms by other halogen atoms
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    • C07C51/00Preparation of carboxylic acids or their salts, halides or anhydrides
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    • C07C51/00Preparation of carboxylic acids or their salts, halides or anhydrides
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    • C07C51/00Preparation of carboxylic acids or their salts, halides or anhydrides
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    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C67/00Preparation of carboxylic acid esters
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    • C07C67/00Preparation of carboxylic acid esters
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    • C07C67/313Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by introduction of doubly bound oxygen containing functional groups, e.g. carboxyl groups
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    • C07C67/00Preparation of carboxylic acid esters
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    • C07C67/317Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by splitting-off hydrogen or functional groups; by hydrogenolysis of functional groups
    • C07C67/327Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by splitting-off hydrogen or functional groups; by hydrogenolysis of functional groups by elimination of functional groups containing oxygen only in singly bound form
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    • C07C67/00Preparation of carboxylic acid esters
    • C07C67/30Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
    • C07C67/333Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton
    • C07C67/343Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
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    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/02Systems containing only non-condensed rings with a three-membered ring

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
FR30712A 1964-09-10 1965-09-07 Nouveaux acides biphényl-acétiques substitués et procédés pour leur préparation Expired FR1460659A (fr)

Priority Applications (5)

Application Number Priority Date Filing Date Title
FR30712A FR1460659A (fr) 1964-09-10 1965-09-07 Nouveaux acides biphényl-acétiques substitués et procédés pour leur préparation
FR41105A FR7047M (US20100056889A1-20100304-C00004.png) 1964-09-10 1965-12-06
FR121826A FR7008M (US20100056889A1-20100304-C00004.png) 1964-09-10 1967-09-21
FR121824A FR7007M (US20100056889A1-20100304-C00004.png) 1964-09-10 1967-09-21
FR121825A FR7048M (US20100056889A1-20100304-C00004.png) 1964-09-10 1967-09-21

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US39555364A 1964-09-10 1964-09-10
FR30712A FR1460659A (fr) 1964-09-10 1965-09-07 Nouveaux acides biphényl-acétiques substitués et procédés pour leur préparation

Publications (1)

Publication Number Publication Date
FR1460659A true FR1460659A (fr) 1966-01-07

Family

ID=23563534

Family Applications (5)

Application Number Title Priority Date Filing Date
FR30712A Expired FR1460659A (fr) 1964-09-10 1965-09-07 Nouveaux acides biphényl-acétiques substitués et procédés pour leur préparation
FR41105A Expired FR7047M (US20100056889A1-20100304-C00004.png) 1964-09-10 1965-12-06
FR121826A Expired FR7008M (US20100056889A1-20100304-C00004.png) 1964-09-10 1967-09-21
FR121825A Expired FR7048M (US20100056889A1-20100304-C00004.png) 1964-09-10 1967-09-21
FR121824A Expired FR7007M (US20100056889A1-20100304-C00004.png) 1964-09-10 1967-09-21

Family Applications After (4)

Application Number Title Priority Date Filing Date
FR41105A Expired FR7047M (US20100056889A1-20100304-C00004.png) 1964-09-10 1965-12-06
FR121826A Expired FR7008M (US20100056889A1-20100304-C00004.png) 1964-09-10 1967-09-21
FR121825A Expired FR7048M (US20100056889A1-20100304-C00004.png) 1964-09-10 1967-09-21
FR121824A Expired FR7007M (US20100056889A1-20100304-C00004.png) 1964-09-10 1967-09-21

Country Status (9)

Country Link
US (1) US3624142A (US20100056889A1-20100304-C00004.png)
BE (1) BE669347A (US20100056889A1-20100304-C00004.png)
BR (1) BR6572746D0 (US20100056889A1-20100304-C00004.png)
CH (1) CH490309A (US20100056889A1-20100304-C00004.png)
ES (1) ES317635A1 (US20100056889A1-20100304-C00004.png)
FR (5) FR1460659A (US20100056889A1-20100304-C00004.png)
GB (4) GB1116435A (US20100056889A1-20100304-C00004.png)
IL (1) IL24046A (US20100056889A1-20100304-C00004.png)
NL (1) NL6511845A (US20100056889A1-20100304-C00004.png)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2016169A1 (US20100056889A1-20100304-C00004.png) * 1968-08-22 1970-05-08 Scherico Ltd
FR2059514A1 (US20100056889A1-20100304-C00004.png) * 1969-07-16 1971-06-04 Bdh Pharmaceuticals Ltd
FR2059497A1 (US20100056889A1-20100304-C00004.png) * 1969-07-09 1971-06-04 Bdh Pharmaceuticals Ltd
FR2295738A1 (fr) * 1972-09-22 1976-07-23 Boots Co Ltd Derives d'acide biphenylylacetique et leurs applications
FR2584403A1 (fr) * 1985-07-08 1987-01-09 Pf Medicament Derives d'alcools primaires halogeno biphenyles utiles en therapeutique dans le traitement de l'atherosclerose
CN114790141A (zh) * 2022-05-25 2022-07-26 大连理工大学 一种无过渡金属催化的氯代烯丙基酯的合成方法

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4053639A (en) * 1964-01-24 1977-10-11 The Boots Company Limited Therapeutically active phenylalkane derivatives
US4163788A (en) 1968-03-27 1979-08-07 Ciba-Geigy Corporation Tertiary aminoacids
US4316850A (en) 1968-03-27 1982-02-23 Ciba-Geigy Corporation Tertiary aminoacids
SE365788B (US20100056889A1-20100304-C00004.png) * 1968-10-25 1974-04-01 Ciba Geigy Ag
US3981905A (en) * 1970-03-16 1976-09-21 Boots Pure Drug Company Limited 2-(Substituted phenyl) propionic acids
US4192890A (en) * 1970-04-15 1980-03-11 Roussel Uclaf Novel benzoylphenylacetic acid esters
US3864384A (en) * 1970-05-05 1975-02-04 Rorer Inc William H Substituted phenylacetic acid compounds
US3941821A (en) * 1970-05-05 1976-03-02 William H. Rorer, Inc. 2-Thiosulfo biphenylylacetic acids
GB1312642A (en) * 1970-07-13 1973-04-04 Science Union & Cie Pyrazole compounds and process for their manufacture
GB1359987A (en) * 1970-10-12 1974-07-17 Boots Co Ltd 2-substituted biphenylyl propionic acids
US4052514A (en) * 1971-03-26 1977-10-04 The Boots Company Limited Trihalosubstituted biphenylyl propionic acids
US3857880A (en) * 1971-07-20 1974-12-31 Schering Corp Cyclopropane carboxylic acid derivatives
BE787782A (fr) * 1971-08-20 1973-02-19 Thomae Gmbh Dr K Nouveaux 4-(4-biphenylyl)-butyramides
DE2205732A1 (de) * 1972-02-08 1973-08-16 Thomae Gmbh Dr K Neue 4-(4-biphenylyl)-butensaeurederivate
GB1396726A (en) * 1972-06-15 1975-06-04 Boots Co Ltd Phenylalkanoic acids
US4048332A (en) * 1972-06-15 1977-09-13 The Boots Company Limited Phenylalkanoic acids
US3987197A (en) * 1972-08-17 1976-10-19 Boehringer Ingelheim Gmbh 3-(2'-fluoro-4-biphenylyl)-butyric acid and salts thereof
DE2341506A1 (de) * 1973-08-16 1975-02-27 Thomae Gmbh Dr K Neue biphenylderivate und verfahren zu ihrer herstellung
US3957861A (en) * 1973-11-07 1976-05-18 The Upjohn Company Biphenylylpropionic acids and esters
GB1497044A (en) * 1974-03-07 1978-01-05 Prodotti Antibiotici Spa Salts of phenyl-alkanoic acids
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FR2016169A1 (US20100056889A1-20100304-C00004.png) * 1968-08-22 1970-05-08 Scherico Ltd
FR2059497A1 (US20100056889A1-20100304-C00004.png) * 1969-07-09 1971-06-04 Bdh Pharmaceuticals Ltd
FR2059514A1 (US20100056889A1-20100304-C00004.png) * 1969-07-16 1971-06-04 Bdh Pharmaceuticals Ltd
FR2295738A1 (fr) * 1972-09-22 1976-07-23 Boots Co Ltd Derives d'acide biphenylylacetique et leurs applications
FR2584403A1 (fr) * 1985-07-08 1987-01-09 Pf Medicament Derives d'alcools primaires halogeno biphenyles utiles en therapeutique dans le traitement de l'atherosclerose
EP0210885A1 (fr) * 1985-07-08 1987-02-04 Pierre Fabre Medicament Dérivés d'alcools primaires halogéno biphényles utiles en thérapeutique dans le traitement de l'athérosclérose
CN114790141A (zh) * 2022-05-25 2022-07-26 大连理工大学 一种无过渡金属催化的氯代烯丙基酯的合成方法
CN114790141B (zh) * 2022-05-25 2023-03-07 大连理工大学 一种无过渡金属催化的氯代烯丙基酯的合成方法

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FR7048M (US20100056889A1-20100304-C00004.png) 1969-06-16
FR7047M (US20100056889A1-20100304-C00004.png) 1969-06-16
GB1116433A (en) 1968-06-06
US3624142A (en) 1971-11-30
CH490309A (de) 1970-05-15
BR6572746D0 (pt) 1973-08-07
NL6511845A (US20100056889A1-20100304-C00004.png) 1966-03-11
ES317635A1 (es) 1966-04-01
GB1116435A (en) 1968-06-06
FR7008M (US20100056889A1-20100304-C00004.png) 1969-06-02
BE669347A (US20100056889A1-20100304-C00004.png) 1966-03-08
FR7007M (US20100056889A1-20100304-C00004.png) 1969-06-02
IL24046A (en) 1970-03-22
GB1116434A (en) 1968-06-06
GB1116432A (en) 1968-06-06

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