FR1460659A - Nouveaux acides biphényl-acétiques substitués et procédés pour leur préparation - Google Patents
Nouveaux acides biphényl-acétiques substitués et procédés pour leur préparationInfo
- Publication number
- FR1460659A FR1460659A FR30712A FR30712A FR1460659A FR 1460659 A FR1460659 A FR 1460659A FR 30712 A FR30712 A FR 30712A FR 30712 A FR30712 A FR 30712A FR 1460659 A FR1460659 A FR 1460659A
- Authority
- FR
- France
- Prior art keywords
- processes
- preparation
- acetic acids
- substituted biphenyl
- new substituted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- YWPABLWXCWUIIT-UHFFFAOYSA-N 2-(2-phenylphenyl)acetic acid Chemical class OC(=O)CC1=CC=CC=C1C1=CC=CC=C1 YWPABLWXCWUIIT-UHFFFAOYSA-N 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/06—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C201/00—Preparation of esters of nitric or nitrous acid or of compounds containing nitro or nitroso groups bound to a carbon skeleton
- C07C201/06—Preparation of nitro compounds
- C07C201/12—Preparation of nitro compounds by reactions not involving the formation of nitro groups
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
- C07C205/45—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by at least one doubly—bound oxygen atom, not being part of a —CHO group
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
- C07C205/49—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups
- C07C205/56—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups bound to carbon atoms of six-membered aromatic rings and carboxyl groups bound to acyclic carbon atoms of the carbon skeleton
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
- C07C205/49—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups
- C07C205/57—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
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- C—CHEMISTRY; METALLURGY
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- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/04—Formation of amino groups in compounds containing carboxyl groups
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C229/52—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/02—Preparation of carboxylic acid amides from carboxylic acids or from esters, anhydrides, or halides thereof by reaction with ammonia or amines
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C253/00—Preparation of carboxylic acid nitriles
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C253/00—Preparation of carboxylic acid nitriles
- C07C253/30—Preparation of carboxylic acid nitriles by reactions not involving the formation of cyano groups
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C303/00—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides
- C07C303/02—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of sulfonic acids or halides thereof
- C07C303/16—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of sulfonic acids or halides thereof by oxidation of thiols, sulfides, hydropolysulfides, or polysulfides with formation of sulfo or halosulfonyl groups
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- C—CHEMISTRY; METALLURGY
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- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C303/00—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides
- C07C303/36—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of amides of sulfonic acids
- C07C303/38—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of amides of sulfonic acids by reaction of ammonia or amines with sulfonic acids, or with esters, anhydrides, or halides thereof
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- C—CHEMISTRY; METALLURGY
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- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C315/00—Preparation of sulfones; Preparation of sulfoxides
- C07C315/02—Preparation of sulfones; Preparation of sulfoxides by formation of sulfone or sulfoxide groups by oxidation of sulfides, or by formation of sulfone groups by oxidation of sulfoxides
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- C07C317/00—Sulfones; Sulfoxides
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- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
- C07C317/44—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
- C07C319/02—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of thiols
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- C—CHEMISTRY; METALLURGY
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- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
- C07C319/14—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides
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- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
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- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
- C07C323/62—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton
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- C—CHEMISTRY; METALLURGY
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- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/004—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reaction with organometalhalides
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- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/41—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by hydrogenolysis or reduction of carboxylic groups or functional derivatives thereof
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- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
- C07C45/46—Friedel-Crafts reactions
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- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/63—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by introduction of halogen; by substitution of halogen atoms by other halogen atoms
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- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/06—Preparation of carboxylic acids or their salts, halides or anhydrides from carboxylic acid amides
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/09—Preparation of carboxylic acids or their salts, halides or anhydrides from carboxylic acid esters or lactones
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
- C07C51/363—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by introduction of halogen; by substitution of halogen atoms by other halogen atoms
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- C—CHEMISTRY; METALLURGY
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- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/30—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings
- C07C57/38—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings polycyclic
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- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/52—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen
- C07C57/58—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings
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- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/52—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen
- C07C57/62—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings and other rings
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- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/42—Unsaturated compounds containing hydroxy or O-metal groups
- C07C59/56—Unsaturated compounds containing hydroxy or O-metal groups containing halogen
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- C07C67/00—Preparation of carboxylic acid esters
- C07C67/14—Preparation of carboxylic acid esters from carboxylic acid halides
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- C07C67/00—Preparation of carboxylic acid esters
- C07C67/30—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
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- C—CHEMISTRY; METALLURGY
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- C07C67/00—Preparation of carboxylic acid esters
- C07C67/30—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
- C07C67/303—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by hydrogenation of unsaturated carbon-to-carbon bonds
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- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
- C07C67/30—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
- C07C67/307—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by introduction of halogen; by substitution of halogen atoms by other halogen atoms
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- C07C67/00—Preparation of carboxylic acid esters
- C07C67/30—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
- C07C67/31—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by introduction of functional groups containing oxygen only in singly bound form
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- C07C67/00—Preparation of carboxylic acid esters
- C07C67/30—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
- C07C67/313—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by introduction of doubly bound oxygen containing functional groups, e.g. carboxyl groups
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- C07C67/00—Preparation of carboxylic acid esters
- C07C67/30—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
- C07C67/317—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by splitting-off hydrogen or functional groups; by hydrogenolysis of functional groups
- C07C67/327—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by splitting-off hydrogen or functional groups; by hydrogenolysis of functional groups by elimination of functional groups containing oxygen only in singly bound form
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- C07C67/00—Preparation of carboxylic acid esters
- C07C67/30—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
- C07C67/333—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton
- C07C67/343—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
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- C—CHEMISTRY; METALLURGY
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- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/02—Systems containing only non-condensed rings with a three-membered ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Priority Applications (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR30712A FR1460659A (fr) | 1964-09-10 | 1965-09-07 | Nouveaux acides biphényl-acétiques substitués et procédés pour leur préparation |
FR41105A FR7047M (fr) | 1964-09-10 | 1965-12-06 | |
FR121825A FR7048M (fr) | 1964-09-10 | 1967-09-21 | |
FR121824A FR7007M (fr) | 1964-09-10 | 1967-09-21 | |
FR121826A FR7008M (fr) | 1964-09-10 | 1967-09-21 |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US39555364A | 1964-09-10 | 1964-09-10 | |
FR30712A FR1460659A (fr) | 1964-09-10 | 1965-09-07 | Nouveaux acides biphényl-acétiques substitués et procédés pour leur préparation |
Publications (1)
Publication Number | Publication Date |
---|---|
FR1460659A true FR1460659A (fr) | 1966-01-07 |
Family
ID=23563534
Family Applications (5)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR30712A Expired FR1460659A (fr) | 1964-09-10 | 1965-09-07 | Nouveaux acides biphényl-acétiques substitués et procédés pour leur préparation |
FR41105A Expired FR7047M (fr) | 1964-09-10 | 1965-12-06 | |
FR121824A Expired FR7007M (fr) | 1964-09-10 | 1967-09-21 | |
FR121825A Expired FR7048M (fr) | 1964-09-10 | 1967-09-21 | |
FR121826A Expired FR7008M (fr) | 1964-09-10 | 1967-09-21 |
Family Applications After (4)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR41105A Expired FR7047M (fr) | 1964-09-10 | 1965-12-06 | |
FR121824A Expired FR7007M (fr) | 1964-09-10 | 1967-09-21 | |
FR121825A Expired FR7048M (fr) | 1964-09-10 | 1967-09-21 | |
FR121826A Expired FR7008M (fr) | 1964-09-10 | 1967-09-21 |
Country Status (9)
Country | Link |
---|---|
US (1) | US3624142A (fr) |
BE (1) | BE669347A (fr) |
BR (1) | BR6572746D0 (fr) |
CH (1) | CH490309A (fr) |
ES (1) | ES317635A1 (fr) |
FR (5) | FR1460659A (fr) |
GB (4) | GB1116433A (fr) |
IL (1) | IL24046A (fr) |
NL (1) | NL6511845A (fr) |
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2016169A1 (fr) * | 1968-08-22 | 1970-05-08 | Scherico Ltd | |
FR2059514A1 (fr) * | 1969-07-16 | 1971-06-04 | Bdh Pharmaceuticals Ltd | |
FR2059497A1 (fr) * | 1969-07-09 | 1971-06-04 | Bdh Pharmaceuticals Ltd | |
FR2295738A1 (fr) * | 1972-09-22 | 1976-07-23 | Boots Co Ltd | Derives d'acide biphenylylacetique et leurs applications |
FR2584403A1 (fr) * | 1985-07-08 | 1987-01-09 | Pf Medicament | Derives d'alcools primaires halogeno biphenyles utiles en therapeutique dans le traitement de l'atherosclerose |
CN114790141A (zh) * | 2022-05-25 | 2022-07-26 | 大连理工大学 | 一种无过渡金属催化的氯代烯丙基酯的合成方法 |
Families Citing this family (40)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4053639A (en) * | 1964-01-24 | 1977-10-11 | The Boots Company Limited | Therapeutically active phenylalkane derivatives |
US4163788A (en) | 1968-03-27 | 1979-08-07 | Ciba-Geigy Corporation | Tertiary aminoacids |
US4316850A (en) | 1968-03-27 | 1982-02-23 | Ciba-Geigy Corporation | Tertiary aminoacids |
SE365788B (fr) * | 1968-10-25 | 1974-04-01 | Ciba Geigy Ag | |
US3981905A (en) * | 1970-03-16 | 1976-09-21 | Boots Pure Drug Company Limited | 2-(Substituted phenyl) propionic acids |
US4192890A (en) * | 1970-04-15 | 1980-03-11 | Roussel Uclaf | Novel benzoylphenylacetic acid esters |
US3941821A (en) * | 1970-05-05 | 1976-03-02 | William H. Rorer, Inc. | 2-Thiosulfo biphenylylacetic acids |
US3864384A (en) * | 1970-05-05 | 1975-02-04 | Rorer Inc William H | Substituted phenylacetic acid compounds |
GB1312642A (en) * | 1970-07-13 | 1973-04-04 | Science Union & Cie | Pyrazole compounds and process for their manufacture |
GB1359987A (en) * | 1970-10-12 | 1974-07-17 | Boots Co Ltd | 2-substituted biphenylyl propionic acids |
US4052514A (en) * | 1971-03-26 | 1977-10-04 | The Boots Company Limited | Trihalosubstituted biphenylyl propionic acids |
US3857880A (en) * | 1971-07-20 | 1974-12-31 | Schering Corp | Cyclopropane carboxylic acid derivatives |
BE787782A (fr) * | 1971-08-20 | 1973-02-19 | Thomae Gmbh Dr K | Nouveaux 4-(4-biphenylyl)-butyramides |
DE2205732A1 (de) * | 1972-02-08 | 1973-08-16 | Thomae Gmbh Dr K | Neue 4-(4-biphenylyl)-butensaeurederivate |
US4048332A (en) * | 1972-06-15 | 1977-09-13 | The Boots Company Limited | Phenylalkanoic acids |
GB1396726A (en) * | 1972-06-15 | 1975-06-04 | Boots Co Ltd | Phenylalkanoic acids |
US3987197A (en) * | 1972-08-17 | 1976-10-19 | Boehringer Ingelheim Gmbh | 3-(2'-fluoro-4-biphenylyl)-butyric acid and salts thereof |
DE2341506A1 (de) * | 1973-08-16 | 1975-02-27 | Thomae Gmbh Dr K | Neue biphenylderivate und verfahren zu ihrer herstellung |
US3957861A (en) * | 1973-11-07 | 1976-05-18 | The Upjohn Company | Biphenylylpropionic acids and esters |
GB1497044A (en) * | 1974-03-07 | 1978-01-05 | Prodotti Antibiotici Spa | Salts of phenyl-alkanoic acids |
US4020094A (en) * | 1974-04-22 | 1977-04-26 | Syntex (U.S.A.) Inc. | 2-Substituted-5-oxo-5H-dibenzo[a,d]cycloheptenes, the salts and esters thereof, having pharmaceutical activity |
US4035509A (en) * | 1974-04-22 | 1977-07-12 | Syntex (U.S.A.) Inc. | Methods and compositions for the use of 2-carboxy-5-oxo-5H-dibenzo[a,d]cycloheptenes, salts and esters thereof |
ES446581A1 (es) * | 1975-04-04 | 1977-06-16 | Boots Co Ltd | Un procedimiento para preparar acidos 2-arilpropionicos. |
US4333951A (en) * | 1977-11-15 | 1982-06-08 | A. H. Robins Company, Inc. | 2-Amino-6-biphenylacetic acids |
US4324904A (en) * | 1979-12-19 | 1982-04-13 | The Upjohn Company | Processes for the preparation of hydratropic acids and esters |
FR2498449A1 (fr) * | 1981-01-23 | 1982-07-30 | Fabre Sa Pierre | Acides halogeno biphenyl carboxyliques et leurs sels utiles en therapeutique |
US4731484A (en) * | 1985-01-18 | 1988-03-15 | The Dow Chemical Company | Haloacetyl derivatives of aromatic compounds |
IT1197289B (it) * | 1986-09-26 | 1988-11-30 | S I F I Societa Ind Farmaceuti | Sale di lisina dell'acido 4-bifenilacetico e sue composizioni oftalmiche |
US5663416A (en) * | 1990-05-22 | 1997-09-02 | Cortech Inc. | Oxidant sensitive and insensitive aromatic esters as inhibitors of human neutrophil elastase |
TW348175B (en) * | 1993-01-06 | 1998-12-21 | Hoechst Ag | Process for the preparation of biphenyl derivatives |
US5691376A (en) * | 1994-02-17 | 1997-11-25 | American Home Products Corporation | Substituted biphenyl derivatives |
AU692839B2 (en) * | 1994-02-17 | 1998-06-18 | American Home Products Corporation | Substituted biphenyl derivatives as phosphodiesterase inhibitors |
US5593994A (en) * | 1994-09-29 | 1997-01-14 | The Dupont Merck Pharmaceutical Company | Prostaglandin synthase inhibitors |
US5789434A (en) * | 1994-11-15 | 1998-08-04 | Bayer Corporation | Derivatives of substituted 4-biarylbutyric acid as matrix metalloprotease inhibitors |
AR002945A1 (es) * | 1994-11-15 | 1998-05-27 | Bayer Corp | Acidos 4-biarilbutirico o 5-biarilpentanoico sustituidos y sus derivados como inhibidores de las metaloproteasas de matriz, composicion que los contiene, y metodos para la preparacion de dichos compuestos |
DK0933346T3 (da) | 1996-07-31 | 2004-03-29 | Shionogi & Co | Nye p-terphenylforbindelser |
US5994379A (en) * | 1998-02-13 | 1999-11-30 | Merck Frosst Canada, Inc. | Bisaryl COX-2 inhibiting compounds, compositions and methods of use |
KR100809489B1 (ko) * | 2001-10-10 | 2008-03-03 | 씨제이제일제당 (주) | 사이클로옥시게나제-2의 저해제로서 선택성이 뛰어난4'-메탄설포닐-비페닐 유도체 |
CN1944378A (zh) * | 2006-10-23 | 2007-04-11 | 广东中科药物研究有限公司 | 一种联苯乙酸氨丁三醇盐及其制备方法 |
CN106748721B (zh) * | 2016-11-17 | 2019-06-21 | 山东铂源药业有限公司 | 一种2-氯-5-碘苯甲酸的制备方法 |
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Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2921939A (en) * | 1955-11-28 | 1960-01-19 | Metal & Thermit Corp | Process for preparing alpha-substituted acetic acids |
FR1152761A (fr) * | 1956-04-07 | 1958-02-25 | Maggioni & C Spa | Procédé pour la préparation d'acides 4-diphénylyl-alkyl-acétiques |
US3043746A (en) * | 1959-11-02 | 1962-07-10 | Vismara Francesco Spa | 2-(4-biphenylyl)-delta-hexenoic acid and derivatives as anticholesterinemic agents |
US3120551A (en) * | 1961-03-20 | 1964-02-04 | Warner Lambert Pharmaceutical | 5-(4-biphenylyl)-3-methylvaleric acid and functional derivatives thereof |
-
1964
- 1964-09-10 US US395553A patent/US3624142A/en not_active Expired - Lifetime
-
1965
- 1965-07-28 IL IL24046A patent/IL24046A/en unknown
- 1965-08-31 BR BR172746/65A patent/BR6572746D0/pt unknown
- 1965-09-01 CH CH1222365A patent/CH490309A/de not_active IP Right Cessation
- 1965-09-07 GB GB38600/67A patent/GB1116433A/en not_active Expired
- 1965-09-07 GB GB38168/65A patent/GB1116432A/en not_active Expired
- 1965-09-07 GB GB38711/67A patent/GB1116434A/en not_active Expired
- 1965-09-07 FR FR30712A patent/FR1460659A/fr not_active Expired
- 1965-09-07 GB GB38712/67A patent/GB1116435A/en not_active Expired
- 1965-09-08 BE BE669347D patent/BE669347A/xx unknown
- 1965-09-09 ES ES0317635A patent/ES317635A1/es not_active Expired
- 1965-09-10 NL NL6511845A patent/NL6511845A/xx unknown
- 1965-12-06 FR FR41105A patent/FR7047M/fr not_active Expired
-
1967
- 1967-09-21 FR FR121824A patent/FR7007M/fr not_active Expired
- 1967-09-21 FR FR121825A patent/FR7048M/fr not_active Expired
- 1967-09-21 FR FR121826A patent/FR7008M/fr not_active Expired
Cited By (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2016169A1 (fr) * | 1968-08-22 | 1970-05-08 | Scherico Ltd | |
FR2059497A1 (fr) * | 1969-07-09 | 1971-06-04 | Bdh Pharmaceuticals Ltd | |
FR2059514A1 (fr) * | 1969-07-16 | 1971-06-04 | Bdh Pharmaceuticals Ltd | |
FR2295738A1 (fr) * | 1972-09-22 | 1976-07-23 | Boots Co Ltd | Derives d'acide biphenylylacetique et leurs applications |
FR2584403A1 (fr) * | 1985-07-08 | 1987-01-09 | Pf Medicament | Derives d'alcools primaires halogeno biphenyles utiles en therapeutique dans le traitement de l'atherosclerose |
EP0210885A1 (fr) * | 1985-07-08 | 1987-02-04 | Pierre Fabre Medicament | Dérivés d'alcools primaires halogéno biphényles utiles en thérapeutique dans le traitement de l'athérosclérose |
CN114790141A (zh) * | 2022-05-25 | 2022-07-26 | 大连理工大学 | 一种无过渡金属催化的氯代烯丙基酯的合成方法 |
CN114790141B (zh) * | 2022-05-25 | 2023-03-07 | 大连理工大学 | 一种无过渡金属催化的氯代烯丙基酯的合成方法 |
Also Published As
Publication number | Publication date |
---|---|
FR7007M (fr) | 1969-06-02 |
CH490309A (de) | 1970-05-15 |
GB1116433A (en) | 1968-06-06 |
ES317635A1 (es) | 1966-04-01 |
BE669347A (fr) | 1966-03-08 |
FR7008M (fr) | 1969-06-02 |
GB1116435A (en) | 1968-06-06 |
IL24046A (en) | 1970-03-22 |
FR7047M (fr) | 1969-06-16 |
BR6572746D0 (pt) | 1973-08-07 |
GB1116432A (en) | 1968-06-06 |
GB1116434A (en) | 1968-06-06 |
FR7048M (fr) | 1969-06-16 |
NL6511845A (fr) | 1966-03-11 |
US3624142A (en) | 1971-11-30 |
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