FR1363948A - Nouvelles bases azotées substituées par au moins un radical naphtyle ou naphtylméthyle - Google Patents

Nouvelles bases azotées substituées par au moins un radical naphtyle ou naphtylméthyle

Info

Publication number
FR1363948A
FR1363948A FR929519A FR929519A FR1363948A FR 1363948 A FR1363948 A FR 1363948A FR 929519 A FR929519 A FR 929519A FR 929519 A FR929519 A FR 929519A FR 1363948 A FR1363948 A FR 1363948A
Authority
FR
France
Prior art keywords
naphthyl
nitrogenous bases
bases substituted
new nitrogenous
naphthylmethyl radical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR929519A
Other languages
English (en)
French (fr)
Inventor
Etienne Szarvasi
Michel Bayssat
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Sante SAS
Original Assignee
LIPHA SAS
LIPHA Liyonnaise Industrielle Pharmaceutique
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to NL142872D priority Critical patent/NL142872C/xx
Application filed by LIPHA SAS, LIPHA Liyonnaise Industrielle Pharmaceutique filed Critical LIPHA SAS
Priority to FR929519A priority patent/FR1363948A/fr
Priority to SE3234/64A priority patent/SE306747B/xx
Priority to SE11642/66A priority patent/SE335351B/xx
Priority to BE645366D priority patent/BE645366A/xx
Priority to US352963A priority patent/US3334096A/en
Priority to GB32352/65A priority patent/GB1022034A/en
Priority to GB12259/64A priority patent/GB1022032A/en
Priority to GB32350/65A priority patent/GB1022033A/en
Priority to DE1493920A priority patent/DE1493920C3/de
Priority to DE1543741A priority patent/DE1543741C3/de
Priority to AT260964A priority patent/AT250339B/de
Priority to AT778864A priority patent/AT247309B/de
Priority to CH1627269A priority patent/CH496636A/fr
Priority to DK152064AA priority patent/DK125702B/da
Priority to CH1627169A priority patent/CH495951A/fr
Priority to CH394364A priority patent/CH483395A/fr
Priority to BR157920/64A priority patent/BR6457920D0/pt
Priority to ES298057A priority patent/ES298057A1/es
Priority to NL646403315A priority patent/NL142872B/xx
Priority to FR977740A priority patent/FR88158E/fr
Publication of FR1363948A publication Critical patent/FR1363948A/fr
Application granted granted Critical
Priority to OA50983A priority patent/OA00893A/xx
Priority to BE664909D priority patent/BE664909A/xx
Priority to DE1595880A priority patent/DE1595880C3/de
Priority to GB24306/65A priority patent/GB1085876A/en
Priority to NL6507424A priority patent/NL6507424A/xx
Priority to NO65159024A priority patent/NO117982B/no
Priority to DK325466AA priority patent/DK118773B/da
Priority to NL7400838A priority patent/NL7400838A/xx
Priority to NL7400837A priority patent/NL7400837A/xx
Priority to NL7400839A priority patent/NL7400839A/xx
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/084—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings
    • C07D295/088—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms attached to the same carbon chain, which is not interrupted by carbocyclic rings to an acyclic saturated chain
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/04—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D307/10—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/12—Radicals substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/04—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D307/10—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/16—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Hydrogenated Pyridines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
FR929519A 1963-03-28 1963-03-28 Nouvelles bases azotées substituées par au moins un radical naphtyle ou naphtylméthyle Expired FR1363948A (fr)

Priority Applications (31)

Application Number Priority Date Filing Date Title
NL142872D NL142872C (US20100268047A1-20101021-C00003.png) 1963-03-28
FR929519A FR1363948A (fr) 1963-03-28 1963-03-28 Nouvelles bases azotées substituées par au moins un radical naphtyle ou naphtylméthyle
SE3234/64A SE306747B (US20100268047A1-20101021-C00003.png) 1963-03-28 1964-03-16
SE11642/66A SE335351B (US20100268047A1-20101021-C00003.png) 1963-03-28 1964-03-16
BE645366D BE645366A (US20100268047A1-20101021-C00003.png) 1963-03-28 1964-03-18
US352963A US3334096A (en) 1963-03-28 1964-03-18 Acid salts of tertiaryaminoethyl beta-(1-naphthyl)-beta-(2-tetrahydrofuryl) isobutyrates
GB32352/65A GB1022034A (en) 1963-03-28 1964-03-23 New alcohols and process for producing the same
GB12259/64A GB1022032A (en) 1963-03-28 1964-03-23 Basic ethers
GB32350/65A GB1022033A (en) 1963-03-28 1964-03-23 Basic esters
DE1543741A DE1543741C3 (de) 1963-03-28 1964-03-24 Aminoäthylester und deren pharmakologisch nicht giftige Salze und Verfahren zu deren Herstellung. Ausscheidung aus: 1493920
DE1493920A DE1493920C3 (de) 1963-03-28 1964-03-24 Aminoäther und deren pharmakologisch nichtgiftige Salze und quaternäre Ammoniumverbindungen mit Methyljodid sowie Verfahren zu deren Herstellung
BR157920/64A BR6457920D0 (pt) 1963-03-28 1964-03-25 Processo de preparacao de novos impostos de bases introgenados substituidos por ao menos um radical maftila ou naftila-metila
AT778864A AT247309B (de) 1963-03-28 1964-03-25 Verfahren zur Herstellung neuer, disubstituierter Alkohole
CH1627269A CH496636A (fr) 1963-03-28 1964-03-25 Procédé de préparation de nouveaux alcools primaires substitués par un radical naphtyle ou naphtyl-méthyle
AT260964A AT250339B (de) 1963-03-28 1964-03-25 Verfahren zur Herstellung von neuen Amino-ester bzw. -äthern
DK152064AA DK125702B (da) 1963-03-28 1964-03-25 Fremgangsmåde til fremstilling af aminoetheroxider med en naphthyl- eller naphthylmethylgruppe eller syreadditionssalte eller kvaternære ammoniumsalte deraf.
CH1627169A CH495951A (fr) 1963-03-28 1964-03-25 Procédé de préparation de nouvelles bases azotées contenant un radical naphtyle ou naphtyl-méthyle
CH394364A CH483395A (fr) 1963-03-28 1964-03-25 Procédé pour la préparation de nouvelles bases azotées contenant un radical naphtyle ou naphtyl-méthyle
ES298057A ES298057A1 (es) 1963-03-28 1964-03-26 Procedimiento de preparación de nuevas bases nitrogenadas
NL646403315A NL142872B (nl) 1963-03-28 1964-03-26 Werkwijze ter bereiding van basische stikstofverbindingen met spasmolytische en/of vaatverwijdende werking; werkwijze ter bereiding van farmaceutische preparaten, alsmede de aldus verkregen voorwerpen.
FR977740A FR88158E (fr) 1963-03-28 1964-06-10 Nouvelles bases azotées substituées par au moins un radical naphtyle ou naphtylméthyle
OA50983A OA00893A (fr) 1963-03-28 1964-12-22 Nouvelles bases azotées substituées par au moins un radical naphtyle ou naphtyl-méthyle.
BE664909D BE664909A (US20100268047A1-20101021-C00003.png) 1963-03-28 1965-06-03
DE1595880A DE1595880C3 (de) 1963-03-28 1965-06-04 Aminopropylester und deren pharmakologisch nicht giftige Salze und Verfahren zu deren Herstellung
GB24306/65A GB1085876A (en) 1963-03-28 1965-06-08 Basic esters of naphthyl-tetrahydrofuryl-isobutyric acid
NL6507424A NL6507424A (US20100268047A1-20101021-C00003.png) 1963-03-28 1965-06-10
NO65159024A NO117982B (US20100268047A1-20101021-C00003.png) 1963-03-28 1965-07-20
DK325466AA DK118773B (da) 1963-03-28 1966-06-24 Fremgangsmåde til fremstilling af aminoestere med mindst én naphthyl- eller naphthylmethylgruppe eller syreadditionssalte deraf.
NL7400838A NL7400838A (US20100268047A1-20101021-C00003.png) 1963-03-28 1974-01-22
NL7400837A NL7400837A (US20100268047A1-20101021-C00003.png) 1963-03-28 1974-01-22
NL7400839A NL7400839A (US20100268047A1-20101021-C00003.png) 1963-03-28 1974-01-22

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR929519A FR1363948A (fr) 1963-03-28 1963-03-28 Nouvelles bases azotées substituées par au moins un radical naphtyle ou naphtylméthyle

Publications (1)

Publication Number Publication Date
FR1363948A true FR1363948A (fr) 1964-06-19

Family

ID=8800292

Family Applications (1)

Application Number Title Priority Date Filing Date
FR929519A Expired FR1363948A (fr) 1963-03-28 1963-03-28 Nouvelles bases azotées substituées par au moins un radical naphtyle ou naphtylméthyle

Country Status (13)

Country Link
US (1) US3334096A (US20100268047A1-20101021-C00003.png)
AT (2) AT250339B (US20100268047A1-20101021-C00003.png)
BE (1) BE645366A (US20100268047A1-20101021-C00003.png)
BR (1) BR6457920D0 (US20100268047A1-20101021-C00003.png)
CH (1) CH483395A (US20100268047A1-20101021-C00003.png)
DE (2) DE1493920C3 (US20100268047A1-20101021-C00003.png)
DK (2) DK125702B (US20100268047A1-20101021-C00003.png)
ES (1) ES298057A1 (US20100268047A1-20101021-C00003.png)
FR (1) FR1363948A (US20100268047A1-20101021-C00003.png)
GB (3) GB1022032A (US20100268047A1-20101021-C00003.png)
NL (5) NL142872B (US20100268047A1-20101021-C00003.png)
NO (1) NO117982B (US20100268047A1-20101021-C00003.png)
SE (2) SE335351B (US20100268047A1-20101021-C00003.png)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2237078A1 (de) * 1971-07-29 1973-05-03 Lipha Tetrahydrofurfurylaminoester mit periphere und cerebrale gefaesse erweiternden eigenschaften
FR2371197A1 (fr) * 1976-11-18 1978-06-16 Bottu Nouveaux derives de l'acide isobutyrique disubstitue ainsi que leur application comme medicaments

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3458529A (en) * 1964-06-10 1969-07-29 Lipha Nitrogenous bases substituted by at least one naphthyl or naphthylmethyl radical
FR5671M (US20100268047A1-20101021-C00003.png) * 1965-04-23 1968-01-02
US4048330A (en) * 1967-01-13 1977-09-13 Syntex Corporation Compositions containing 2-(6'-substituted-2'-naphthyl)acetic acid esters used for treating inflammation, pain or pyrexia
US3896157A (en) * 1967-01-13 1975-07-22 Syntex Corp Dihydo 2-naphthylacetic acid derivatives
US3973033A (en) * 1971-07-29 1976-08-03 Lipha, Lyonnaise Industrielle Pharmaceutique Compositions and methods for producing a vasodilatory effect with a naphthyl tetrahydrofurfuryl amino-ester
US3975390A (en) * 1973-07-26 1976-08-17 Richter Gedeon Vegyeszeti Gyar Rt. N-methyl substituted piperazino nitrobenzophenones and a process for the preparation thereof
FR2377196A1 (fr) * 1977-01-13 1978-08-11 Lipha Composition medicamenteuse a usage oral
HU177876B (en) * 1979-04-24 1982-01-28 Nitrokemia Ipartelepek Process for preparing 2,6-dialkyl-n-/alkoxy-methyl/-chloro-acetanilide derivatives
FR2505836A1 (fr) * 1981-05-14 1982-11-19 Sanofi Sa Citrate de naftidrofuryl et son application therapeutique
FR2580502B1 (fr) * 1985-04-23 1988-07-08 Lipha Emploi du " naftidrofuryl " dans la preparation d'un medicament
JPH0662521B2 (ja) * 1988-02-24 1994-08-17 日東紡績株式会社 新規コリン誘導体及びそれを用いた血清コリンエステラーゼ活性測定法
ES2362998T3 (es) 2002-08-19 2011-07-18 Pfizer Inc. Terapia de combinación para enfermedades hiperproliferativas.
US20050037063A1 (en) * 2003-07-21 2005-02-17 Bolton Anthony E. Combined therapies
US20060063803A1 (en) * 2004-09-23 2006-03-23 Pfizer Inc 4-Amino substituted-2-substituted-1,2,3,4-tetrahydroquinoline compounds
US7741317B2 (en) 2005-10-21 2010-06-22 Bristol-Myers Squibb Company LXR modulators
US7888376B2 (en) 2005-11-23 2011-02-15 Bristol-Myers Squibb Company Heterocyclic CETP inhibitors
ATE547394T1 (de) 2006-12-01 2012-03-15 Bristol Myers Squibb Co N-((3-benzyl)-2,2-(bis-phenyl)-propan-1- aminderivate als cetp-hemmer für die behandlung von atherosklerose und herz-kreislauf- erkrankungen
KR101695582B1 (ko) 2013-04-17 2017-01-13 화이자 인코포레이티드 심혈관 질환을 치료하기 위한 n-피페리딘-3-일벤즈아미드 유도체
WO2016055901A1 (en) 2014-10-08 2016-04-14 Pfizer Inc. Substituted amide compounds
EA202191892A1 (ru) 2019-01-18 2022-02-24 Астразенека Аб Ингибиторы pcsk9 и способы их применения

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2417208A (en) * 1943-08-04 1947-03-11 Geigy Ag J R Basic esters of monoalkyl isobutyl acetic acids
CH396872A (de) * 1959-08-13 1965-08-15 Ciba Geigy Verfahren zur Herstellung neuer Harnstoffe
US3242174A (en) * 1962-02-06 1966-03-22 Pfizer & Co C 1-(tertiary aminosulfonyl)-3-(hydrocarbon) ureas

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2237078A1 (de) * 1971-07-29 1973-05-03 Lipha Tetrahydrofurfurylaminoester mit periphere und cerebrale gefaesse erweiternden eigenschaften
FR2371197A1 (fr) * 1976-11-18 1978-06-16 Bottu Nouveaux derives de l'acide isobutyrique disubstitue ainsi que leur application comme medicaments

Also Published As

Publication number Publication date
DK125702B (da) 1973-03-26
DK118773B (da) 1970-10-05
NL7400838A (US20100268047A1-20101021-C00003.png) 1974-04-25
NL7400837A (US20100268047A1-20101021-C00003.png) 1974-04-25
NL7400839A (US20100268047A1-20101021-C00003.png) 1974-04-25
DE1543741A1 (de) 1969-12-11
BE645366A (US20100268047A1-20101021-C00003.png) 1964-09-18
GB1022034A (en) 1966-03-09
ES298057A1 (es) 1964-06-01
NL142872B (nl) 1974-08-15
BR6457920D0 (pt) 1973-02-22
NL6403315A (US20100268047A1-20101021-C00003.png) 1964-09-29
DE1493920A1 (de) 1969-07-10
SE306747B (US20100268047A1-20101021-C00003.png) 1968-12-09
CH483395A (fr) 1969-12-31
DE1543741C3 (de) 1974-02-07
SE335351B (US20100268047A1-20101021-C00003.png) 1971-05-24
GB1022032A (en) 1966-03-09
DE1493920B2 (de) 1973-06-20
AT250339B (de) 1966-11-10
GB1022033A (en) 1966-03-09
DE1493920C3 (de) 1974-01-17
DE1543741B2 (de) 1973-07-05
US3334096A (en) 1967-08-01
AT247309B (de) 1966-06-10
NL142872C (US20100268047A1-20101021-C00003.png)
NO117982B (US20100268047A1-20101021-C00003.png) 1969-10-20

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