FR10C0012I1 - - Google Patents

Info

Publication number
FR10C0012I1
FR10C0012I1 FR10C0012C FR10C0012I1 FR 10C0012 I1 FR10C0012 I1 FR 10C0012I1 FR 10C0012 C FR10C0012 C FR 10C0012C FR 10C0012 I1 FR10C0012 I1 FR 10C0012I1
Authority
FR
France
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9449457&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=FR10C0012(I1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed filed Critical
Publication of FR10C0012I1 publication Critical patent/FR10C0012I1/fr
Application granted granted Critical
Publication of FR10C0012I2 publication Critical patent/FR10C0012I2/fr
Active legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • C07D519/04—Dimeric indole alkaloids, e.g. vincaleucoblastine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
FR10C0012C 1993-07-21 2010-03-04 Active FR10C0012I2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9308948A FR2707988B1 (fr) 1993-07-21 1993-07-21 Nouveaux dérivés antimitotiques des alcaloïdes binaires du catharantus rosesus, leur procédé de préparation et les compositions pharmaceutiques les comprenant.
PCT/FR1994/000898 WO1995003312A1 (fr) 1993-07-21 1994-07-19 Derives antimitotiques des alcaloides binaires du catharanthus roseus

Publications (2)

Publication Number Publication Date
FR10C0012I1 true FR10C0012I1 (fr) 2010-04-16
FR10C0012I2 FR10C0012I2 (fr) 2011-04-01

Family

ID=9449457

Family Applications (2)

Application Number Title Priority Date Filing Date
FR9308948A Expired - Lifetime FR2707988B1 (fr) 1993-07-21 1993-07-21 Nouveaux dérivés antimitotiques des alcaloïdes binaires du catharantus rosesus, leur procédé de préparation et les compositions pharmaceutiques les comprenant.
FR10C0012C Active FR10C0012I2 (fr) 1993-07-21 2010-03-04

Family Applications Before (1)

Application Number Title Priority Date Filing Date
FR9308948A Expired - Lifetime FR2707988B1 (fr) 1993-07-21 1993-07-21 Nouveaux dérivés antimitotiques des alcaloïdes binaires du catharantus rosesus, leur procédé de préparation et les compositions pharmaceutiques les comprenant.

Country Status (15)

Country Link
US (1) US5620985A (fr)
EP (1) EP0710240B1 (fr)
JP (1) JP3606872B2 (fr)
AT (1) ATE146477T1 (fr)
AU (1) AU693460B2 (fr)
BR (1) BR1100311A (fr)
CA (1) CA2167694C (fr)
DE (2) DE69401216T2 (fr)
DK (1) DK0710240T3 (fr)
ES (1) ES2097659T3 (fr)
FR (2) FR2707988B1 (fr)
GR (1) GR3022659T3 (fr)
LU (1) LU91660I2 (fr)
NZ (2) NZ269172A (fr)
WO (1) WO1995003312A1 (fr)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
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FR2737208A1 (fr) * 1995-07-28 1997-01-31 Pf Medicament Nouvelles fluorovindolines, precurseurs d'analogues de la vinblastine et de la vinorelbine,leurs procedes de preparation et leur utilisation comme medicament
FR2761990B1 (fr) 1997-04-10 1999-06-25 Pf Medicament Derives halogenes antimitotiques d'alcaloides de vinca
FR2783522A1 (fr) * 1998-09-21 2000-03-24 Pf Medicament Composes derives d'alcaloides de vinca, leur preparation et leur application en therapeutique
GB0011903D0 (en) * 2000-05-18 2000-07-05 Astrazeneca Ab Combination chemotherapy
US6890558B2 (en) * 2002-05-31 2005-05-10 R.P. Scherer Technologies, Inc. Oral pharmaceutical composition for soft capsules containing vinorelbine and method of treatment
AU2004296191B2 (en) 2003-12-04 2010-10-28 Albany Molecular Research, Inc. Vinca derivatives
WO2005055943A2 (fr) 2003-12-04 2005-06-23 Amr Technology, Inc. Derives de la vinorelbine
FR2863891B1 (fr) * 2003-12-23 2006-03-24 Pf Medicament Composition pharmaceutique de vinflunine destinee a une administration parentale, procede de preparation et utilisation
US20110015221A1 (en) * 2003-12-23 2011-01-20 Pierre Fabre Medicament Pharmaceutical composition of vinflunine which is intended for parenteral administration preparation method thereof and use of same
ATE507240T1 (de) * 2004-03-05 2011-05-15 Vegenics Pty Ltd Materialien und verfahren für wachstumsfaktorbindende konstrukte
FR2894966B1 (fr) * 2005-12-20 2008-03-14 Pierre Fabre Medicament Sa Nouvelle forme cristalline de la vinflunine
CN101421282B (zh) 2006-02-17 2013-08-14 俄勒冈州由俄勒冈州立大学代表高等教育委员会行使 用长春花生物碱n-氧化物和类似物治疗过度增殖性疾病
CN101108859A (zh) * 2006-07-17 2008-01-23 上海恒瑞医药有限公司 长春碱类化合物、其制备方法及其在医药上的用途
WO2008033935A2 (fr) * 2006-09-12 2008-03-20 Amr Technology, Inc. Dérivés de la vinorelbine
US8039453B2 (en) * 2006-09-12 2011-10-18 Albany Molecular Research, Inc. Vinca derivatives
FR2905949B1 (fr) * 2006-09-20 2008-11-21 Pierre Fabre Medicament Sa Derives fluores de catharanthine, leur preparation et leur utilisation comme precurseurs d'alcaloides dimeres de vinca
CN101235046B (zh) * 2007-01-29 2010-09-08 中国科学院上海药物研究所 长春碱衍生物、其制备方法和用途、以及包含该衍生物的药物组合物
FR2912406B1 (fr) * 2007-02-13 2009-05-08 Pierre Fabre Medicament Sa Sels cristalins anhydres de vinflunine, procede de preparation et utilisation en tant que medicament et moyen de purification de la vinflunine.
EP1997534A1 (fr) * 2007-05-31 2008-12-03 Pierre Fabre Medicament Thérapie de combinaison de traitement du cancer comportant de la vinflunine et trastuzumab
FR2918566B1 (fr) 2007-07-11 2009-10-09 Pierre Fabre Medicament Sa Composition pharmaceutique stable d'un sel hydrosoluble de vinflunine.
FR2918567B1 (fr) * 2007-07-11 2012-08-03 Pf Medicament Composition pharmaceutique stable d'un sel hydrosoluble de vinorelbine.
US20090076055A1 (en) * 2007-09-14 2009-03-19 Protia, Llc Deuterium-enriched vinflunine
US8173621B2 (en) 2008-06-11 2012-05-08 Gilead Pharmasset Llc Nucleoside cyclicphosphates
PA8855601A1 (es) 2008-12-23 2010-07-27 Forformidatos de nucleósidos
CA2748034A1 (fr) 2008-12-23 2010-07-01 Pharmasset, Inc. Promedicaments de 2'-deoxy'2'-fluoro-2'-c-methyl-nucleoside-phosphoramidate purifie destines au traitement d'infections virales
CN102325783A (zh) 2008-12-23 2012-01-18 法莫赛特股份有限公司 嘌呤核苷的合成
DK2547359T3 (en) 2010-03-15 2016-06-06 The Board Of Trustees Of The Univ Of Illionis Inhibitors of beta integrin G-protein alpha subunit-BINDING INTERACTIONS
SG184323A1 (en) 2010-03-31 2012-11-29 Gilead Pharmasett Llc Stereoselective synthesis of phosphorus containing actives
EP2655401B1 (fr) 2010-12-20 2016-03-09 The Regents of the University of Michigan Inhibiteurs de l'interaction de liaison entre le récepteur du facteur de croissance épidermique et la protéine de choc thermique 90
CN103788117A (zh) * 2012-10-30 2014-05-14 何小解 一种脱水长春碱、长春瑞滨及长春氟宁连续化合成工艺
HU230462B1 (hu) 2013-05-30 2016-07-28 Richter Gedeon Nyrt. Új bisz-indol alkaloidok mint rákellenes gyógyszerek
US9783547B2 (en) 2014-01-15 2017-10-10 Centre National De La Recherche Scientifique (Cnrs) Water soluble 4-azapodophyllotoxin analogs
US10308719B2 (en) 2015-01-26 2019-06-04 The University Of Chicago IL13Rα2 binding agents and use thereof in cancer treatment
CN107835820B (zh) 2015-01-26 2021-10-15 芝加哥大学 识别癌症特异性IL13Rα2的CAR T细胞
RU2730521C2 (ru) * 2016-03-09 2020-08-24 Синбиас Фарма АГ Винорелбина монотартрат и его фармацевтическое применение
WO2018007554A1 (fr) 2016-07-06 2018-01-11 Pierre Fabre Medicament Combinaison pharmaceutique comprenant la vinflunine et l'inhibiteur de pd1 et/ou de pdl1
AU2018314227A1 (en) 2017-08-07 2020-02-06 Amgen Inc. Treatment of triple negative breast cancer or colorectal cancer with liver metastases with an anti PD-L1 antibody and an oncolytic virus
CN114174340A (zh) 2019-03-20 2022-03-11 加利福尼亚大学董事会 密封蛋白-6抗体和药物缀合物
BR112021021663A2 (pt) 2019-04-30 2022-05-17 Inst De Medicina Molecular Joao Lobo Antunes Inibidores da via rank em combinação com inibidores de cdk
CA3140904A1 (fr) 2019-06-24 2020-12-30 Amgen Inc. Inhibition de la sirp-gamma pour le traitement du cancer
FR3140369A1 (fr) 2022-10-04 2024-04-05 Universite De Poitiers Procédé de fluoration et/ou cyclisation d’un alcène ou alcyne aminé en flux continu et installation pour la mise en œuvre du procédé

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2296418B1 (fr) * 1974-12-30 1978-07-21 Anvar
US4110330A (en) * 1977-05-27 1978-08-29 Eli Lilly And Company 5'-Acetonylvincristine and related compounds
US4203898A (en) * 1977-08-29 1980-05-20 Eli Lilly And Company Amide derivatives of VLB, leurosidine, leurocristine and related dimeric alkaloids
US4307100A (en) * 1978-08-24 1981-12-22 Agence Nationale De Valorisation De La Recherche (Anvar) Nor bis-indole compounds usable as medicaments
US4320058A (en) * 1980-12-29 1982-03-16 Eli Lilly And Company 20'-Hydroxyvinblastine and related compounds
HU193772B (en) * 1985-06-12 1987-11-30 Richter Gedeon Vegyeszet Process for producing new nitro-bis-indole derivatives

Also Published As

Publication number Publication date
AU693460B2 (en) 1998-07-02
NZ269172A (en) 1997-10-24
ES2097659T3 (es) 1997-04-01
DE122010000012I1 (de) 2010-07-08
FR10C0012I2 (fr) 2011-04-01
FR2707988A1 (fr) 1995-01-27
DE69401216D1 (de) 1997-01-30
BR1100311A (pt) 1999-08-31
CA2167694A1 (fr) 1995-02-02
ATE146477T1 (de) 1997-01-15
EP0710240A1 (fr) 1996-05-08
LU91660I2 (fr) 2010-05-10
GR3022659T3 (en) 1997-05-31
DE69401216T2 (de) 1997-07-03
DK0710240T3 (da) 1997-06-02
NZ328612A (en) 2000-05-26
WO1995003312A1 (fr) 1995-02-02
CA2167694C (fr) 2007-03-06
US5620985A (en) 1997-04-15
AU7266694A (en) 1995-02-20
JP3606872B2 (ja) 2005-01-05
FR2707988B1 (fr) 1995-10-13
EP0710240B1 (fr) 1996-12-18
JPH09500634A (ja) 1997-01-21

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