FI990171A - Uusia yhdisteitä ja koostumuksia tryptaasiaktiivisuuden liittyvien tautien hoitamiseksi - Google Patents
Uusia yhdisteitä ja koostumuksia tryptaasiaktiivisuuden liittyvien tautien hoitamiseksi Download PDFInfo
- Publication number
- FI990171A FI990171A FI990171A FI990171A FI990171A FI 990171 A FI990171 A FI 990171A FI 990171 A FI990171 A FI 990171A FI 990171 A FI990171 A FI 990171A FI 990171 A FI990171 A FI 990171A
- Authority
- FI
- Finland
- Prior art keywords
- compositions
- treatment
- novel compounds
- diseases related
- tryptase activity
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/20—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/20—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
- C07D295/215—Radicals derived from nitrogen analogues of carbonic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/26—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D233/06—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to ring carbon atoms
- C07D233/08—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to ring carbon atoms with alkyl radicals, containing more than four carbon atoms, directly attached to ring carbon atoms
- C07D233/12—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to ring carbon atoms with alkyl radicals, containing more than four carbon atoms, directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D233/14—Radicals substituted by oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US2313996P | 1996-07-30 | 1996-07-30 | |
| US89577297A | 1997-07-17 | 1997-07-17 | |
| PCT/US1997/013422 WO1998004537A1 (fr) | 1996-07-30 | 1997-07-30 | Nouveaux composes et compositions servant a traiter des maladies associees a l'activite de tryptase |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FI990171A0 FI990171A0 (fi) | 1999-01-29 |
| FI990171A true FI990171A (fi) | 1999-03-23 |
Family
ID=26696778
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI990171A FI990171A (fi) | 1996-07-30 | 1999-01-29 | Uusia yhdisteitä ja koostumuksia tryptaasiaktiivisuuden liittyvien tautien hoitamiseksi |
Country Status (17)
| Country | Link |
|---|---|
| EP (1) | EP0934293A1 (fr) |
| JP (1) | JP2001509787A (fr) |
| KR (1) | KR20000029679A (fr) |
| CN (1) | CN1073103C (fr) |
| AU (1) | AU733621B2 (fr) |
| CA (1) | CA2262542A1 (fr) |
| CZ (1) | CZ29799A3 (fr) |
| EE (1) | EE9900036A (fr) |
| FI (1) | FI990171A (fr) |
| HU (1) | HUP0003267A3 (fr) |
| LV (1) | LV12291B (fr) |
| NO (1) | NO990433L (fr) |
| NZ (1) | NZ333713A (fr) |
| PL (1) | PL331465A1 (fr) |
| SI (1) | SI9720047A (fr) |
| SK (1) | SK8599A3 (fr) |
| WO (1) | WO1998004537A1 (fr) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6221914B1 (en) | 1997-11-10 | 2001-04-24 | Array Biopharma Inc. | Sulfonamide bridging compounds that inhibit tryptase activity |
| EP1060175B1 (fr) * | 1998-02-06 | 2004-11-17 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Inhibiteurs de la tryptase |
| WO1999040073A2 (fr) * | 1998-02-06 | 1999-08-12 | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. | Inhibiteurs de la tryptase |
| EP1115731A2 (fr) * | 1998-09-04 | 2001-07-18 | Byk Gulden Lomberg Chemische Fabrik GmbH | Nouvelles pyranoses |
| KR20020016942A (ko) | 1999-08-10 | 2002-03-06 | 빅 굴덴 롬베르크 케미쉐 파브릭 게엠베하 | 디아조신-디온 유도체 및 이것의 트립타제 억제제로서 용도 |
| EP1216236A1 (fr) * | 1999-09-14 | 2002-06-26 | Byk Gulden Lomberg Chemische Fabrik GmbH | Inhibiteurs de la tryptase |
| WO2001036386A1 (fr) * | 1999-11-17 | 2001-05-25 | Sumitomo Pharmaceuticals Co., Ltd. | Traitement du diabete contenant un derive de dipiperazine |
| DE19955476A1 (de) * | 1999-11-18 | 2001-05-23 | Boehringer Ingelheim Pharma | Bis-basische Verbindungen als Tryptase-Inhibitoren, Verfahren zu deren Herstellung sowie deren Verwendung als Arzneimittel |
| AU783217B2 (en) * | 1999-12-20 | 2005-10-06 | Altana Pharma Ag | Tryptase inhibitors |
| AU783371B2 (en) | 1999-12-20 | 2005-10-20 | Altana Pharma Ag | Tryptase inhibitors |
| ES2225758T3 (es) | 2001-01-31 | 2005-03-16 | Altana Pharma Ag | Derivdos de diazocina y su uso como agentes inhibidores de la triptasa. |
| AU2002253026B2 (en) * | 2001-02-21 | 2007-08-09 | Altana Pharma Ag | Tryptase inhibitors |
| JP2004518736A (ja) | 2001-02-21 | 2004-06-24 | アルタナ ファルマ アクチエンゲゼルシャフト | トリプターゼインヒビター |
| WO2002074732A2 (fr) * | 2001-03-15 | 2002-09-26 | Altana Pharma Ag | Inhibiteurs de la tryptase |
| US20040087792A1 (en) * | 2001-03-15 | 2004-05-06 | Thomas Martin | Tryptase-inhibitors |
| US8048917B2 (en) | 2005-04-06 | 2011-11-01 | Xenoport, Inc. | Prodrugs of GABA analogs, compositions and uses thereof |
| US7186855B2 (en) | 2001-06-11 | 2007-03-06 | Xenoport, Inc. | Prodrugs of GABA analogs, compositions and uses thereof |
| US6818787B2 (en) | 2001-06-11 | 2004-11-16 | Xenoport, Inc. | Prodrugs of GABA analogs, compositions and uses thereof |
| EP2085087A1 (fr) | 2001-06-11 | 2009-08-05 | Xenoport, Inc. | Promédicaments d'analogues gaba, compositions et leurs utilisations |
| ATE348803T1 (de) | 2001-06-19 | 2007-01-15 | Altana Pharma Ag | Tryptase-inhibitoren |
| RU2440112C2 (ru) | 2004-11-04 | 2012-01-20 | Ксенопорт, Инк. | Пероральная дозированная форма габапентина замедленного высвобождения |
| AU2009328497A1 (en) | 2008-12-19 | 2010-06-24 | Merz Pharma Gmbh & Co. Kgaa | 1-amino-alkylcyclohexane derivatives for the treatment of mast cell mediated diseases |
| TWI432188B (zh) | 2008-12-19 | 2014-04-01 | Merz Pharma Gmbh & Co Kgaa | 供治療發炎性皮膚疾病之１－胺基－烷基環己烷衍生物類 |
| FR3038605B1 (fr) | 2015-07-06 | 2018-08-24 | Universite Amiens Picardie Jules Verne | Diamines primaires vicinales associees a des motifs chelateurs de metaux et/ou de radicaux libres, actives contre les stress carbonyle et oxydant et leur utilisation |
| CN110869362A (zh) * | 2017-05-12 | 2020-03-06 | 国立研究开发法人理化学研究所 | A类gpcr结合性化合物改性体 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4845242A (en) * | 1987-04-28 | 1989-07-04 | Georgia Tech Research Corporation | Isocoumarins with basic substituents as serine proteases inhibitors, anticoagulants and anti-inflammatory agents |
| AU683459B2 (en) * | 1993-03-12 | 1997-11-13 | Arris Pharmaceutical Corporation | Compositions and methods for the treatment of immunomediated inflammatory disorders |
| US5525623A (en) * | 1993-03-12 | 1996-06-11 | Arris Pharmaceutical Corporation | Compositions and methods for the treatment of immunomediated inflammatory disorders |
| WO1995032945A1 (fr) * | 1994-06-01 | 1995-12-07 | Arris Pharmaceutical Corporation | Compositions et procedes de traitement d'etats induits par des mastocytes |
| AU694275B2 (en) * | 1994-09-23 | 1998-07-16 | Arris Pharmaceutical Corporation | Compositions and methods for treating mast-cell inflammatory conditions |
| PL322409A1 (en) * | 1995-03-24 | 1998-01-19 | Arris Pharm Corp | Reversible protease inhibitors |
| TW438591B (en) * | 1995-06-07 | 2001-06-07 | Arris Pharm Corp | Reversible cysteine protease inhibitors |
-
1997
- 1997-07-30 CN CN97196877A patent/CN1073103C/zh not_active Expired - Fee Related
- 1997-07-30 EE EEP199900036A patent/EE9900036A/xx unknown
- 1997-07-30 NZ NZ333713A patent/NZ333713A/xx unknown
- 1997-07-30 JP JP50913698A patent/JP2001509787A/ja active Pending
- 1997-07-30 AU AU39670/97A patent/AU733621B2/en not_active Ceased
- 1997-07-30 SI SI9720047A patent/SI9720047A/sl unknown
- 1997-07-30 SK SK85-99A patent/SK8599A3/sk unknown
- 1997-07-30 HU HU0003267A patent/HUP0003267A3/hu unknown
- 1997-07-30 WO PCT/US1997/013422 patent/WO1998004537A1/fr not_active Application Discontinuation
- 1997-07-30 PL PL97331465A patent/PL331465A1/xx unknown
- 1997-07-30 CZ CZ99297A patent/CZ29799A3/cs unknown
- 1997-07-30 EP EP97937066A patent/EP0934293A1/fr not_active Withdrawn
- 1997-07-30 CA CA002262542A patent/CA2262542A1/fr not_active Abandoned
- 1997-07-30 KR KR1019997000757A patent/KR20000029679A/ko not_active Application Discontinuation
-
1999
- 1999-01-29 FI FI990171A patent/FI990171A/fi unknown
- 1999-01-29 NO NO990433A patent/NO990433L/no not_active Application Discontinuation
- 1999-02-18 LV LVP-99-27A patent/LV12291B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PL331465A1 (en) | 1999-07-19 |
| CZ29799A3 (cs) | 1999-06-16 |
| CN1226892A (zh) | 1999-08-25 |
| KR20000029679A (ko) | 2000-05-25 |
| LV12291A (lv) | 1999-06-20 |
| NO990433D0 (no) | 1999-01-29 |
| EP0934293A1 (fr) | 1999-08-11 |
| WO1998004537A1 (fr) | 1998-02-05 |
| CA2262542A1 (fr) | 1998-02-05 |
| SK8599A3 (en) | 2000-03-13 |
| AU733621B2 (en) | 2001-05-17 |
| NO990433L (no) | 1999-03-25 |
| HUP0003267A3 (en) | 2002-02-28 |
| CN1073103C (zh) | 2001-10-17 |
| FI990171A0 (fi) | 1999-01-29 |
| LV12291B (en) | 2000-04-20 |
| HUP0003267A2 (hu) | 2001-06-28 |
| AU3967097A (en) | 1998-02-20 |
| EE9900036A (et) | 1999-08-16 |
| JP2001509787A (ja) | 2001-07-24 |
| NZ333713A (en) | 2000-12-22 |
| SI9720047A (sl) | 1999-08-31 |
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