FI982436A0 - Kondenserade heterocycliska föreningar - Google Patents

Kondenserade heterocycliska föreningar

Info

Publication number
FI982436A0
FI982436A0 FI982436A FI982436A FI982436A0 FI 982436 A0 FI982436 A0 FI 982436A0 FI 982436 A FI982436 A FI 982436A FI 982436 A FI982436 A FI 982436A FI 982436 A0 FI982436 A0 FI 982436A0
Authority
FI
Finland
Prior art keywords
substituted
condensed heterocyclic
whole number
heterocyclic compounds
atom
Prior art date
Application number
FI982436A
Other languages
English (en)
Finnish (fi)
Other versions
FI982436A (sv
Inventor
Giichi Goto
Yuji Ishihara
Masaomi Miyamoto
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of FI982436A publication Critical patent/FI982436A/sv
Publication of FI982436A0 publication Critical patent/FI982436A0/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Neurology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Containers Having Bodies Formed In One Piece (AREA)
  • Hydrogenated Pyridines (AREA)
FI982436A 1990-11-22 1998-11-10 Kondenserade heterocycliska föreningar FI982436A0 (sv)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP31989790 1990-11-22
JP7028691 1991-01-14
JP20935891 1991-08-21
JP24376891 1991-09-24

Publications (2)

Publication Number Publication Date
FI982436A FI982436A (sv) 1998-11-10
FI982436A0 true FI982436A0 (sv) 1998-11-10

Family

ID=27465225

Family Applications (2)

Application Number Title Priority Date Filing Date
FI915488A FI102965B (sv) 1990-11-22 1991-11-21 Förfarande för framställning av nya kondenserade heterocykliska föreni ngar
FI982436A FI982436A0 (sv) 1990-11-22 1998-11-10 Kondenserade heterocycliska föreningar

Family Applications Before (1)

Application Number Title Priority Date Filing Date
FI915488A FI102965B (sv) 1990-11-22 1991-11-21 Förfarande för framställning av nya kondenserade heterocykliska föreni ngar

Country Status (19)

Country Link
US (1) US5273974A (sv)
EP (1) EP0487071B1 (sv)
JP (1) JP2650537B2 (sv)
KR (1) KR100211437B1 (sv)
CN (1) CN1036458C (sv)
AT (1) ATE124695T1 (sv)
AU (1) AU643337B2 (sv)
CA (1) CA2055947C (sv)
DE (1) DE69111029T2 (sv)
DK (1) DK0487071T3 (sv)
ES (1) ES2074205T3 (sv)
FI (2) FI102965B (sv)
GR (1) GR3017366T3 (sv)
HU (2) HU214573B (sv)
IE (1) IE68346B1 (sv)
NO (1) NO179868C (sv)
NZ (1) NZ240676A (sv)
RU (1) RU2095361C1 (sv)
TW (1) TW197435B (sv)

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US5965574A (en) * 1996-08-13 1999-10-12 Chen; Yuhpyng Liang Heteroaryl amines as novel acetylcholinesterase inhibitors
TW263504B (sv) * 1991-10-03 1995-11-21 Pfizer
TW218875B (sv) * 1992-03-09 1994-01-11 Takeda Pharm Industry Co Ltd
US5462934A (en) * 1992-03-09 1995-10-31 Takeda Chemical Industries Condensed heterocyclic ketone derivatives and their use
EP0567090B1 (en) 1992-04-24 2000-07-26 Takeda Chemical Industries, Ltd. Benzoxazepine derivatives as cholinesterase inhibitors
TW248556B (sv) * 1993-01-18 1995-06-01 Takeda Pharm Industry Co
US5620973A (en) * 1993-11-30 1997-04-15 Takeda Chemical Industries, Ltd. Tetracyclic condensed heterocyclic compounds and their use
ES2301161T3 (es) * 1994-07-27 2008-06-16 Vanderbilt University Compuestos de dihidrobenzofurano y compuestos relacionados utiles como agentes anti-inflamatorios.
US5656661A (en) * 1994-07-27 1997-08-12 The Procter & Gamble Company Dihydrobenzofuran and related compounds useful as anti-inflammatory agents
US5684031A (en) * 1996-02-01 1997-11-04 The Procter & Gamble Company Dihydrobenzofuran and related compounds useful as anti-inflammatory agents
US5672620A (en) * 1996-02-01 1997-09-30 The Procter & Gamble Company Dihydrobenzofuran and related compounds useful as anti-inflammatory agents
US6251938B1 (en) 1996-12-18 2001-06-26 Teva Pharmaceutical Industries, Ltd., Phenylethylamine derivatives
EP0966435B1 (en) 1996-12-18 2005-04-06 Teva Pharmaceutical Industries, Ltd. Aminoindan derivatives
DE69802498T2 (de) * 1997-01-17 2002-07-04 Takeda Chemical Industries, Ltd. Idebenon enthaltendes kombinationspräparat zur alzheimer behandlung
US5962535A (en) * 1997-01-17 1999-10-05 Takeda Chemical Industries, Ltd. Composition for alzheimer's disease
AU6852898A (en) 1997-04-17 1998-11-11 Takeda Chemical Industries Ltd. Thermogenic composition and benzazepine thermogenics
AU3534799A (en) 1998-04-23 1999-11-08 Takeda Chemical Industries Ltd. Pharmaceutical composition for neurotrophic action
CN1163224C (zh) 1998-09-30 2004-08-25 武田药品工业株式会社 改善膀胱排泄能力的药物
ATE277011T1 (de) * 1999-03-03 2004-10-15 Eisai Co Ltd Flouride von 4-substituierten piperidin-derivaten
WO2002002530A1 (fr) * 2000-07-04 2002-01-10 Takeda Chemical Industries, Ltd. Antagoniste de gpr14
AU2001277750A1 (en) * 2000-08-10 2002-02-25 Takeda Chemical Industries Ltd. Use of polypeptide
CN1317276C (zh) * 2000-09-29 2007-05-23 中国科学院上海药物研究所 一类吲哚基哌啶类化合物及其制备方法和用途
JP3878178B2 (ja) 2001-12-28 2007-02-07 武田薬品工業株式会社 排尿障害予防治療剤
US20040010038A1 (en) * 2002-02-27 2004-01-15 Eran Blaugrund Propargylamino indan derivatives and propargylamino tetralin derivatives as brain-selective MAO inhibitors
ES2379948T3 (es) 2002-06-14 2012-05-07 Toyama Chemical Co., Ltd. Composición medicinal que comprende Tacrine o Donepezil para mejorar la función cerebral
EP1572215B1 (en) 2002-12-20 2009-09-02 Glaxo Group Limited Benzo[d]azepine derivatives for the treatment of neurological disorders
JPWO2006004201A1 (ja) * 2004-07-01 2008-04-24 エーザイ・アール・アンド・ディー・マネジメント株式会社 神経再生促進剤
US20080188510A1 (en) * 2005-05-23 2008-08-07 Eisai R & D Management Co., Ltd. Novel methods using zonisamide
CN103142570A (zh) * 2005-12-09 2013-06-12 耶路撒冷希伯来大学伊森姆研究发展公司 低剂量Ladostigil 用于神经保护的用途
TW200744576A (en) * 2006-02-24 2007-12-16 Teva Pharma Propargylated aminoindans, processes for preparation, and uses thereof
WO2010007382A1 (en) * 2008-07-18 2010-01-21 Takeda Pharmaceutical Company Limited. Benzazepine derivatives and their use as hstamine h3 antagonists
WO2011100373A1 (en) 2010-02-09 2011-08-18 The Johns Hopkins University Methods and compositions for improving cognitive function
JP6440625B2 (ja) 2012-11-14 2018-12-19 ザ・ジョンズ・ホプキンス・ユニバーシティー 精神分裂病を処置するための方法および組成物
CA2904767C (en) 2013-03-15 2022-06-21 Agenebio, Inc. Methods and compositions for improving cognitive function
WO2014144663A1 (en) 2013-03-15 2014-09-18 The Johns Hopkins University Methods and compositions for improving cognitive function
US10925834B2 (en) 2015-05-22 2021-02-23 Agenebio, Inc. Extended release pharmaceutical compositions of levetiracetam
CN109880635B (zh) * 2019-03-19 2021-02-02 石家庄晶奥量新材料有限公司 含有二苯并呋喃并含氧杂环类液晶化合物和组合物及应用

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2334358A1 (fr) * 1975-12-12 1977-07-08 Sogeras Nouveaux medicaments derives de l'indole
US4208417A (en) * 1978-06-29 1980-06-17 Pharmindustrie Indole derivatives and their use as anxiolytics
DK623586A (da) * 1985-12-27 1987-06-28 Eisai Co Ltd Piperidinderivater eller salte deraf og farmaceutiske kompositioner indeholdende forbindelserne
KR910006138B1 (ko) * 1986-09-30 1991-08-16 에자이 가부시끼가이샤 환상아민 유도체
FI95572C (sv) * 1987-06-22 1996-02-26 Eisai Co Ltd Förfarande för framställning av ett som läkemedel användbart piperidinderivat eller dess farmaceutiska salt
FR2640266B2 (fr) * 1988-07-12 1992-07-10 Synthelabo Derives de (hydroxy-1 piperidinyl-2 alkyl) indolones-2, quinoleinones-2, benzo(b)azepinones-2 et benzimidazolones-2, leur preparation et leur application en therapeutique
JP2969359B2 (ja) * 1989-01-13 1999-11-02 武田薬品工業株式会社 環状アミン化合物
CA2023492A1 (en) * 1989-08-31 1991-03-01 Barry Clifford Lange Herbicidal glutarimides
US5109002A (en) * 1989-09-08 1992-04-28 Du Pont Merck Pharmaceutical Company Antipsychotic 1-cycloalkylpiperidines

Also Published As

Publication number Publication date
NO179868B (no) 1996-09-23
KR100211437B1 (ko) 1999-08-02
JP2650537B2 (ja) 1997-09-03
RU2095361C1 (ru) 1997-11-10
FI102965B1 (sv) 1999-03-31
HU211130A9 (en) 1995-10-30
FI102965B (sv) 1999-03-31
IE68346B1 (en) 1996-06-12
NO179868C (no) 1997-01-02
FI982436A (sv) 1998-11-10
CA2055947A1 (en) 1992-05-23
KR920009823A (ko) 1992-06-25
DE69111029T2 (de) 1995-12-14
AU8804591A (en) 1992-05-28
HU913643D0 (en) 1992-02-28
DK0487071T3 (da) 1995-10-30
GR3017366T3 (en) 1995-12-31
AU643337B2 (en) 1993-11-11
CA2055947C (en) 2002-03-12
TW197435B (sv) 1993-01-01
IE914053A1 (en) 1992-06-03
EP0487071B1 (en) 1995-07-05
US5273974A (en) 1993-12-28
HUT59676A (en) 1992-06-29
EP0487071A1 (en) 1992-05-27
FI915488A (fi) 1992-05-23
NZ240676A (en) 1993-05-26
JPH05140149A (ja) 1993-06-08
FI915488A0 (fi) 1991-11-21
HU214573B (hu) 2000-04-28
CN1036458C (zh) 1997-11-19
NO914558D0 (no) 1991-11-21
ES2074205T3 (es) 1995-09-01
NO914558L (no) 1992-05-25
DE69111029D1 (de) 1995-08-10
ATE124695T1 (de) 1995-07-15
CN1062143A (zh) 1992-06-24

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