FI973255A0 - Karbatsoliyhdisteiden käyttö verentungosta aiheuttavan sydämen toiminnanvajauksen hoidossa - Google Patents

Karbatsoliyhdisteiden käyttö verentungosta aiheuttavan sydämen toiminnanvajauksen hoidossa

Info

Publication number
FI973255A0
FI973255A0 FI973255A FI973255A FI973255A0 FI 973255 A0 FI973255 A0 FI 973255A0 FI 973255 A FI973255 A FI 973255A FI 973255 A FI973255 A FI 973255A FI 973255 A0 FI973255 A0 FI 973255A0
Authority
FI
Finland
Prior art keywords
treatment
congestive heart
carvedilol
carbonate sol
sol compounds
Prior art date
Application number
FI973255A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI973255A (fi
Inventor
Mary Ann Lukas-Laskey
Jr Robert Ruffolo
Neil Shusterman
Gisbert Sponer
Klaus Strein
Original Assignee
Boehringer Mannheim Pharm Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26012210&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=FI973255(A0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from DE1995103995 external-priority patent/DE19503995C2/de
Application filed by Boehringer Mannheim Pharm Corp filed Critical Boehringer Mannheim Pharm Corp
Publication of FI973255A publication Critical patent/FI973255A/fi
Publication of FI973255A0 publication Critical patent/FI973255A0/fi

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
FI973255A 1995-02-08 1997-08-07 Karbatsoliyhdisteiden käyttö verentungosta aiheuttavan sydämen toiminnanvajauksen hoidossa FI973255A0 (fi)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE1995103995 DE19503995C2 (de) 1995-02-08 1995-02-08 Verwendung von Carvedilol zur Verminderung der Mortalität bei Patienten mit eingeschränkter myocardialer Funktion
US08/483,635 US5760069A (en) 1995-02-08 1995-06-07 Method of treatment for decreasing mortality resulting from congestive heart failure
PCT/EP1996/000498 WO1996024348A2 (en) 1995-02-08 1996-02-07 Use of carbazole compounds for the treatment of congestive heart failure

Publications (2)

Publication Number Publication Date
FI973255A FI973255A (fi) 1997-08-07
FI973255A0 true FI973255A0 (fi) 1997-08-07

Family

ID=26012210

Family Applications (1)

Application Number Title Priority Date Filing Date
FI973255A FI973255A0 (fi) 1995-02-08 1997-08-07 Karbatsoliyhdisteiden käyttö verentungosta aiheuttavan sydämen toiminnanvajauksen hoidossa

Country Status (27)

Country Link
US (6) US5760069A (zh)
EP (1) EP0808162B1 (zh)
JP (1) JP3546058B2 (zh)
KR (1) KR100295940B1 (zh)
CN (1) CN1093760C (zh)
AT (1) ATE179891T1 (zh)
AU (1) AU702106C (zh)
BR (1) BR9607111A (zh)
CA (1) CA2212548C (zh)
CZ (1) CZ292002B6 (zh)
DE (1) DE69602424T2 (zh)
DK (1) DK0808162T3 (zh)
ES (1) ES2134588T3 (zh)
FI (1) FI973255A0 (zh)
GR (1) GR3030966T3 (zh)
HK (1) HK1014861A1 (zh)
HU (1) HUP9900773A3 (zh)
NO (1) NO314830B1 (zh)
NZ (1) NZ301692A (zh)
PL (1) PL321737A1 (zh)
RO (1) RO121629B1 (zh)
RU (1) RU2197242C2 (zh)
SI (1) SI0808162T1 (zh)
SK (1) SK106897A3 (zh)
UA (1) UA55382C2 (zh)
WO (1) WO1996024348A2 (zh)
ZA (1) ZA96994B (zh)

Families Citing this family (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5760069A (en) 1995-02-08 1998-06-02 Boehringer Mannheim Pharmaceuticals Corporation-Smithkline Beecham Corporation Limited Partnership #1 Method of treatment for decreasing mortality resulting from congestive heart failure
BR9712283A (pt) * 1996-10-09 1999-08-31 Boehringer Mannheim Pharm Corp Método para inibir as cinases de proteìnas ativadas por tensão
ZA989365B (en) * 1997-10-15 1999-04-15 Boehringer Mannheim Pharm Corp Preparation for treating alzheimer's disease
HUP0004345A3 (en) * 1997-11-12 2001-10-29 Boehringer Mannheim Pharm Corp Novel oral pharmaceutical compositions containing from carvedilol
US20020054911A1 (en) * 2000-05-11 2002-05-09 Boehringer Mannheim Pharmaceutical Corporation-Sm Ithkline Beckman Corporation, Limited Partnershi Novel oral dosage form for carvedilol
DE19833119A1 (de) * 1998-07-23 2000-01-27 Roche Diagnostics Gmbh Spritzfertige Injektionslösungen enthaltend Carvedilol
US6664284B2 (en) 1998-07-23 2003-12-16 Roche Diagnostics Gmbh Stabilized carvedilol injection solution
PE20001302A1 (es) * 1998-11-27 2000-11-30 Hoffmann La Roche Preparaciones de una combinacion farmaceutica que contiene carvedilol e hidroclorotiazida
CA2383974A1 (en) * 1999-09-08 2001-03-15 Nitromed Inc. Methods of treating and preventing congestive heart failure with hydralazine compounds and isosorbide dinitrate or isosorbide mononitrate
US7235237B2 (en) * 1999-10-29 2007-06-26 Nitromed, Inc. Methods of treating vascular diseases characterized by nitric oxide insufficiency
WO2001035961A1 (en) * 1999-10-29 2001-05-25 Nitromed, Inc. Methods of treating vascular diseases characterized by nitric oxide insufficiency
US7708989B2 (en) * 1999-10-29 2010-05-04 Nitromed, Inc. Methods of treating vascular diseases characterized by nitric oxide insufficiency
US7537785B2 (en) * 1999-10-29 2009-05-26 Nitromed, Inc. Composition for treating vascular diseases characterized by nitric oxide insufficiency
US20010036959A1 (en) * 2000-04-03 2001-11-01 Gabel Rolf Dieter Carvedilol-hydrophilic solutions
WO2002000216A1 (en) * 2000-06-28 2002-01-03 Teva Pharmaceutical Industries Ltd. Carvedilol
WO2003079972A2 (en) 2002-02-22 2003-10-02 New River Parmaceuticals Inc. Active agent delivery systems and methods for protecting and administering active agents
JP2004525941A (ja) * 2001-04-02 2004-08-26 スミスクライン・ビーチャム・コーポレイション 治療方法
WO2003028718A1 (en) * 2001-10-01 2003-04-10 Smithkline Beecham Corporation Novel formulations of carvedilol
US20040186158A1 (en) * 2001-10-02 2004-09-23 Oh Choon K. Novel composition of carvedilol
US8101209B2 (en) 2001-10-09 2012-01-24 Flamel Technologies Microparticulate oral galenical form for the delayed and controlled release of pharmaceutical active principles
SE0103749D0 (sv) * 2001-11-08 2001-11-08 Sahltech Ab Treatment of congestive heart failure
WO2003059807A2 (en) * 2002-01-15 2003-07-24 Teva Pharmaceutical Industries Ltd. Crystalline solids of carvedilol and processes for their preparation
AU2003231283A1 (en) * 2002-04-30 2003-11-17 Sb Pharmco Puerto Rico Inc. Carvedilol monocitrate monohydrate
WO2004047724A2 (en) * 2002-05-16 2004-06-10 Genelabs Technologies, Inc Aryl and heteroaryl compounds as antibacterial and antifungal agents
WO2004002472A1 (en) * 2002-06-27 2004-01-08 Sb Pharmco Puerto Rico Inc. Carvedilol hydrobromide
BR0312102A (pt) * 2002-06-27 2007-05-29 Sb Pharmco Inc sais de fosfato de carvedilol e/ou seus solvatos, composições correspondentes, e/ou métodos de tratamento
SI1362590T1 (en) * 2002-07-25 2004-04-30 Boehringer Ingelheim Pharma Gmbh & Co. Kg Use of cilobradine or the pharmaceutically acceptable salts thereof for the treatment or prevention of heart failure
US6632832B1 (en) 2002-09-10 2003-10-14 Dabur Research Foundation Anti-cancer activity of carvedilol and its isomers
US20050032879A1 (en) * 2003-08-07 2005-02-10 Temple Okarter Formulations and use of a beta-blocker and an ACE-inhibitor for the treatment of cardiovascular diseases
EP1686967A4 (en) * 2003-11-25 2012-08-08 Smithkline Beecham Cork Ltd CARVEDILOL-FREE BASE, SALTS, WATER-FREE FORMS OR SOLVATES THEREOF, CORRESPONDING PHARMACEUTICAL COMPOSITIONS, CONTROLLED RELEASE FORMULAS AND TREATMENT OR DISPOSAL PROCEDURES
JP2007512372A (ja) * 2003-11-25 2007-05-17 エスビー・ファルムコ・プエルト・リコ・インコーポレイテッド カルベジロール塩、対応する組成物、送達および／または治療方法
WO2005051322A2 (en) * 2003-11-25 2005-06-09 Sb Pharmco Puerto Rico Inc. Controlled release pharmaceutical formulations comprising carvedilol, free based and its salts
US20060014829A1 (en) * 2004-07-16 2006-01-19 Nitromed, Inc. Methods for reducing hospitalizations related to heart failure
EP1781611A1 (en) * 2005-06-09 2007-05-09 Teva Pharmaceutical Industries Ltd. Crystalline forms of carvedilol and processes for their preparation
WO2007097951A2 (en) * 2006-02-17 2007-08-30 Nitromed, Inc. Methods using hydralazine compounds and isosorbide dinitrate or isosorbide mononitrate
US8367112B2 (en) * 2006-02-28 2013-02-05 Alkermes Pharma Ireland Limited Nanoparticulate carverdilol formulations
WO2007144785A2 (en) * 2006-03-26 2007-12-21 Uti Limited Partnership Ryanodine receptor inhibitors and methods relating thereto
EP2024337A4 (en) * 2006-05-16 2011-09-14 Nitromed Inc SOLID DOSAGE FORMULATIONS OF HYDRALAZIN COMPOUNDS
EP1991527A2 (en) * 2006-06-28 2008-11-19 Teva Pharmaceutical Industries Ltd Polymorphous forms of carvedilol phosphate
EP2114881A1 (en) * 2007-02-26 2009-11-11 Teva Pharmaceutical Industries Ltd. Process for the purification of carvedilol or its salts thereof
US20090076116A1 (en) * 2007-09-13 2009-03-19 Protia, Llc Deuterium-enriched carvediolo
CA2724540C (en) 2008-05-16 2014-07-08 Corthera, Inc. Treating dyspnea associated with acute heart failure with relaxin
WO2011130194A2 (en) 2010-04-12 2011-10-20 Supernus Pharmaceuticals Inc. Methods for producing viloxazine salts and novel polymorphs thereof
MX2014001556A (es) 2011-08-12 2014-03-31 Boehringer Ingelheim Vetmed Composicion farmaceutica de sabor enmascarado.
CA3027368A1 (en) * 2016-06-13 2017-12-21 Ascendia Pharmaceuticals, Llc Parenteral sustained-release delivery of carvedilol disperse systems
US10772869B1 (en) 2019-07-24 2020-09-15 ECI Pharmaceuticals, LLC Pharmaceutical compositions including carvedilol and methods of using the same

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2815926A1 (de) 1978-04-13 1979-10-18 Boehringer Mannheim Gmbh Neue carbazolyl-(4)-oxy-propanolamin-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3319027A1 (de) 1983-05-26 1984-11-29 Boehringer Mannheim Gmbh, 6800 Mannheim Verfahren zur herstellung von optisch aktiven carbazol-derivaten, neue r- und s-carbazol-derivate, sowie arzneimittel, die diese verbindungen enthalten
SE460945B (sv) * 1987-01-15 1989-12-11 Lejus Medical Ab En multipel-unit-dos komposition av furosemid
US5312828A (en) * 1989-06-14 1994-05-17 Finkelstein Joseph A Substituted imidazoles having angiotensin II receptor blocking activity
US5308862A (en) * 1993-03-05 1994-05-03 Boehringer Mannheim Pharmaceuticals Corporation - Smithkline Beecham Corp., Ltd. Partnership No. 1 Use of, and method of treatment using, carbazolyl-(4)-oxypropanolamine compounds for inhibition of smooth muscle cell proliferation
US5760069A (en) 1995-02-08 1998-06-02 Boehringer Mannheim Pharmaceuticals Corporation-Smithkline Beecham Corporation Limited Partnership #1 Method of treatment for decreasing mortality resulting from congestive heart failure

Also Published As

Publication number Publication date
NO314830B1 (no) 2003-06-02
JPH10513463A (ja) 1998-12-22
RO121629B1 (ro) 2008-01-30
HK1014861A1 (en) 1999-10-08
DK0808162T3 (da) 1999-11-15
ES2134588T3 (es) 1999-10-01
CN1185106A (zh) 1998-06-17
UA55382C2 (uk) 2003-04-15
WO1996024348A2 (en) 1996-08-15
RU2197242C2 (ru) 2003-01-27
CA2212548A1 (en) 1996-08-15
US20010044455A1 (en) 2001-11-22
FI973255A (fi) 1997-08-07
US20030105138A1 (en) 2003-06-05
DE69602424T2 (de) 1999-10-07
USRE40707E1 (en) 2009-05-05
US5902821A (en) 1999-05-11
HUP9900773A3 (en) 2000-04-28
SK106897A3 (en) 1999-03-12
USRE40000E1 (en) 2008-01-08
DE69602424D1 (de) 1999-06-17
CN1093760C (zh) 2002-11-06
GR3030966T3 (en) 1999-11-30
BR9607111A (pt) 1997-11-04
WO1996024348A3 (en) 1996-10-03
KR100295940B1 (ko) 2001-08-07
EP0808162B1 (en) 1999-05-12
HUP9900773A2 (hu) 1999-07-28
CZ292002B6 (cs) 2003-07-16
AU702106C (en) 2005-02-17
US5760069A (en) 1998-06-02
ZA96994B (en) 1997-10-27
JP3546058B2 (ja) 2004-07-21
AU4718196A (en) 1996-08-27
NZ301692A (en) 2000-09-29
CZ246397A3 (cs) 1998-11-11
EP0808162A2 (en) 1997-11-26
ATE179891T1 (de) 1999-05-15
PL321737A1 (en) 1997-12-22
SI0808162T1 (en) 1999-10-31
AU702106B2 (en) 1999-02-11
NO973667D0 (no) 1997-08-08
MX9706042A (es) 1998-06-30
KR19980702085A (ko) 1998-07-15
CA2212548C (en) 1999-08-24
NO973667L (no) 1997-08-08

Similar Documents

Publication Publication Date Title
FI973255A0 (fi) Karbatsoliyhdisteiden käyttö verentungosta aiheuttavan sydämen toiminnanvajauksen hoidossa
UA74346C2 (uk) Похідні амінодикарбонових кислот, їх застосування та лікарський засіб
TR200102962T2 (tr) Yeni tedavi metodu.
GEP20053470B (en) N-Heteroaryl-Pyridinesulfonamide Derivatives and Their Use as Endothelin Antagonists
DK0506539T3 (da) heterocykliske alkylamider, fremgangsmåde til fremstilling heraf og farmaceutiske midler, som indeholder dem
FI964332A (fi) Eräiden metaanibisfosfonihappojohdannaisten käyttö proteesin löystymisen ja proteesin vaelluksen estämiseen
EP0746313A4 (en) METHOD FOR TREATING SMALL Mouth Ulcers
MX9602442A (es) Un tratamiento con fluoroquinolona a dosis unica elevada.
DE69424777D1 (de) 3,4-diarylchromane zur behandlung von dermatitis
SG49692A1 (en) Process for the production of a pharmaceutical agent for oral or topical administration in the treatment of leishmaniasis
HRP950115B1 (en) The use of carboxylic acid derivatives as medicaments
EP1284265A4 (en) BENZOTHIOPHENE DERIVATIVES AND MEDICINAL USE THEREOF
DE69227583D1 (de) Arylmorpholine, herstellung und verwendung
NZ308260A (en) Use of 5-(substituted biphenyl)-tetrazole derivatives to treat multiple system organ failure
ATE167399T1 (de) Verwendung von sulfasalazin und/oder dessen aktiven metaboliten zur herstellung eines arzneimittels zur behandlung von venöser insuffizienz und venösen ulcera
DE68905657D1 (de) Verwendung von arginin-aspartat zur herstellung eines arzneimittels zur behandlung gewisser gedaechtnisstoerungen.
FR2376661A1 (fr) Medicaments anthelminthiques renfermant comme substances actives des anilinomethylene-malononitriles
AU4361996A (en) The use of inositoltrisphosphate for the preparing of medicaments
ES2118451T3 (es) Preparado medicamentoso oral que contiene diclofenaco sodico y un acido organico.
ATE330597T1 (de) Verwendung von fibrate zur herstellung eines arzneimittel zur behandlung von kongestiven herzversagens
AU4578501A (en) Method for treating congestive heart failure
UA35912A (uk) Спосіб лікування виразкової хвороби шлунку та дванадцятипалої кишки
UA22022A (uk) Спосіб лікуваhhя хворих з високим ризиком розвитку поліоргаhhої hедостатhості
YU15301A (sh) PRIMENA R (+)- alfa-(2,3-DIMETOKSIFENIL)-1-[2-(4-FLUOROFENIL) ETIL] -4-PIPERIDINMETANOLA ZA LECENJE POREMEĆAJA SPAVANJA
SU1352938A1 (ru) Питательная среда для получения энтеротоксина clostridium perfringens типа а штамма э