FI971935A - Polyanjoniska bensylglykosider som inhibitorer mot förökning av glatta muskelceller - Google Patents

Polyanjoniska bensylglykosider som inhibitorer mot förökning av glatta muskelceller Download PDF

Info

Publication number
FI971935A
FI971935A FI971935A FI971935A FI971935A FI 971935 A FI971935 A FI 971935A FI 971935 A FI971935 A FI 971935A FI 971935 A FI971935 A FI 971935A FI 971935 A FI971935 A FI 971935A
Authority
FI
Finland
Prior art keywords
image
smooth muscle
proliferation
polyanionic
inhibitors
Prior art date
Application number
FI971935A
Other languages
English (en)
Finnish (fi)
Other versions
FI971935A0 (sv
Inventor
Sarah Tobin Allen Novak
Richard Michael Soll
John Watson Ellingboe
Nguyen Thomas The
Original Assignee
American Home Prod
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Home Prod filed Critical American Home Prod
Publication of FI971935A0 publication Critical patent/FI971935A0/sv
Publication of FI971935A publication Critical patent/FI971935A/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
FI971935A 1994-11-07 1997-05-06 Polyanjoniska bensylglykosider som inhibitorer mot förökning av glatta muskelceller FI971935A (sv)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/335,278 US5498775A (en) 1994-11-07 1994-11-07 Polyanionic benzylglycosides as inhibitors of smooth muscle cell proliferation
PCT/US1995/014686 WO1996014323A1 (en) 1994-11-07 1995-11-03 Polyanionic benzylglycosides as inhibitors of smooth muscle cell proliferation

Publications (2)

Publication Number Publication Date
FI971935A0 FI971935A0 (sv) 1997-05-06
FI971935A true FI971935A (sv) 1997-05-06

Family

ID=23311066

Family Applications (1)

Application Number Title Priority Date Filing Date
FI971935A FI971935A (sv) 1994-11-07 1997-05-06 Polyanjoniska bensylglykosider som inhibitorer mot förökning av glatta muskelceller

Country Status (18)

Country Link
US (1) US5498775A (sv)
EP (1) EP0791006B1 (sv)
JP (1) JPH10508606A (sv)
KR (1) KR970707139A (sv)
AT (1) ATE189227T1 (sv)
AU (1) AU702104B2 (sv)
BR (1) BR9509606A (sv)
DE (1) DE69514823T2 (sv)
DK (1) DK0791006T3 (sv)
ES (1) ES2141395T3 (sv)
FI (1) FI971935A (sv)
GR (1) GR3032629T3 (sv)
IL (1) IL115746A (sv)
MX (1) MX9703282A (sv)
NZ (1) NZ296828A (sv)
PT (1) PT791006E (sv)
WO (1) WO1996014323A1 (sv)
ZA (1) ZA959444B (sv)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6515009B1 (en) 1991-09-27 2003-02-04 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US5811447A (en) 1993-01-28 1998-09-22 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US6251920B1 (en) 1993-05-13 2001-06-26 Neorx Corporation Prevention and treatment of cardiovascular pathologies
US6306421B1 (en) 1992-09-25 2001-10-23 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US5770609A (en) 1993-01-28 1998-06-23 Neorx Corporation Prevention and treatment of cardiovascular pathologies
US5595722A (en) 1993-01-28 1997-01-21 Neorx Corporation Method for identifying an agent which increases TGF-beta levels
US6663881B2 (en) 1993-01-28 2003-12-16 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US5981568A (en) 1993-01-28 1999-11-09 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US6491938B2 (en) 1993-05-13 2002-12-10 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
EP0833624B1 (en) 1995-06-07 2007-11-07 Poniard Pharmaceuticals, Inc. Prevention and treatment of cardiovascular pathologies with tamoxifen analogues
US7611533B2 (en) * 1995-06-07 2009-11-03 Cook Incorporated Coated implantable medical device
EP0840606B1 (en) * 1995-06-29 2000-06-07 Texas Biotechnology Corporation Di- and trivalent small molecule selectin inhibitors
US6001159A (en) * 1995-08-31 1999-12-14 Ricoh Company, Ltd. Reversible thermosensitive coloring composition and reversible thermosensitive recording medium using the same
US5919768A (en) * 1996-06-26 1999-07-06 Texas Biotechnology Corporation Di- and trivalent small molecule selectin inhibitors
US6258784B1 (en) 1998-11-24 2001-07-10 American Home Products Corp. Acetal benzylmaltosides as inhibitors of smooth muscle cell proliferation
US6451767B1 (en) 1998-11-24 2002-09-17 Wyeth Benzylmaltotriosides as inhibitors of smooth muscle cell proliferation
US6187755B1 (en) 1998-11-24 2001-02-13 American Home Products Corporation Benzylmaltosides as inhibitors of smooth muscle cell proliferation
US7132402B2 (en) * 1998-11-24 2006-11-07 Wyeth Acylated benzylmaltosides as inhibitors of smooth muscle cell proliferation
US7081448B2 (en) * 1998-11-24 2006-07-25 Wyeth Benzyllactobionamides as inhibitors of smooth muscle cell proliferation
US6340670B1 (en) 1998-11-24 2002-01-22 American Home Products Corporation Acetal benzylmaltosides as inhibitors of smooth muscle cell proliferation
US6339064B1 (en) 1998-11-24 2002-01-15 American Home Products Corporation Benzylglycosylamides as inhibitors of smooth muscle cell proliferation
US6664243B1 (en) 1998-11-24 2003-12-16 Wyeth Benzyllactobionamides as inhibitors of smooth muscle cell proliferation
US6291434B1 (en) 1998-11-24 2001-09-18 American Home Products Corp. Benzylmaltotriosides as inhibitors of smooth muscle cell proliferation
CA2351059A1 (en) * 1998-11-24 2000-06-15 American Home Products Corporation Acylated benzylmaltosides as inhibitors of smooth muscle cell proliferation
US6362170B1 (en) 1998-11-24 2002-03-26 American Home Products Corporation Benzylglycosylamides as inhibitors of smooth muscle cell proliferation
WO2008102932A1 (en) 2007-02-21 2008-08-28 Biobud Co., Ltd. Compositions for treating hyperproliferative vascular disorders and cancers

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4431636A (en) * 1982-05-24 1984-02-14 American Cyanamid Company Bis(4-O-polyhexaose-thio)-phenyl ureas and method of use
US4431638A (en) * 1982-10-25 1984-02-14 American Cyanamid Company Poly-cation salts of bis(or tris)[4-0-monohexose-thio]-arylene sulfate derivatives
US4431637A (en) * 1982-10-25 1984-02-14 American Cyanamid Company Polycation salts of bis (or tris) [4-O-polyhexose-oxy]-arylene sulfate derivatives
US4435387A (en) * 1982-10-25 1984-03-06 American Cyanamid Company Poly-cation salts of bis (or tris) 4-O-polyhexose-thio-arylene sulfate derivatives
DE3734853A1 (de) * 1987-10-14 1989-04-27 Luitpold Werk Chem Pharm Bis-aldonsaeureamide und verfahren zu ihrer herstellung
DE3734815A1 (de) * 1987-10-14 1989-04-27 Luitpold Werk Chem Pharm Polyschwefelsaeureester von bis-aldonsaeureamiden und deren derivaten, verfahren zu ihrer herstellung und arzneimittel
US5019562A (en) * 1988-01-19 1991-05-28 The Trustees Of The University Of Pennsylvania/Childrens Hospital Corporation Growth inhibiting agent and the use thereof
FR2634485B1 (fr) * 1988-07-21 1992-02-28 Sanopi Glycosaminoglycanes selectivement o-acyles, leur preparation et compositions pharmaceutiques les contenant
US5032679A (en) * 1988-12-15 1991-07-16 Glycomed, Inc. Heparin fragments as inhibitors of smooth muscle cell proliferation
DE69100275T2 (de) * 1990-04-23 1993-12-02 Akzo Nv Eine Trisaccharideinheit enthaltende Kohlenhydratderivate.
WO1993009790A1 (en) * 1991-11-11 1993-05-27 The Trustees Of The University Of Pennsylvania Methods of inhibiting restenosis

Also Published As

Publication number Publication date
ZA959444B (en) 1997-08-07
KR970707139A (ko) 1997-12-01
NZ296828A (en) 1999-04-29
ATE189227T1 (de) 2000-02-15
DE69514823D1 (de) 2000-03-02
DE69514823T2 (de) 2000-10-12
BR9509606A (pt) 1997-10-28
DK0791006T3 (da) 2000-04-17
WO1996014323A1 (en) 1996-05-17
AU702104B2 (en) 1999-02-11
IL115746A0 (en) 1996-01-19
FI971935A0 (sv) 1997-05-06
AU4154996A (en) 1996-05-31
IL115746A (en) 1999-11-30
ES2141395T3 (es) 2000-03-16
PT791006E (pt) 2000-06-30
EP0791006A2 (en) 1997-08-27
MX9703282A (es) 1997-08-30
EP0791006B1 (en) 2000-01-26
GR3032629T3 (en) 2000-05-31
JPH10508606A (ja) 1998-08-25
US5498775A (en) 1996-03-12

Similar Documents

Publication Publication Date Title
FI971935A (sv) Polyanjoniska bensylglykosider som inhibitorer mot förökning av glatta muskelceller
NZ335013A (en) Compositions comprising cytosine derivatives for the treatment of cancer
FI810389L (fi) Foerfarande foer framstaellning av substituerade imidazolderivat
MX9703286A (es) Inhibidores de la proliferacion celular en musculo liso.
DK0791004T3 (da) Acylerede benzylglykosider som inhibitorer af glat-muskelceller-proliferation
UA49089C2 (uk) Похідні вуглеводів та фармацевтична композиція на їх основі
SE8406302D0 (sv) New aminoguanidine derivatives and a process for the preparation thereof
CA2204204A1 (en) Carbohydrate derivatives
AU2406700A (en) 3,4-dihydro-2h-benzo(1,4)oxazinyl-methyl(3-(1h-indol-3-yl)-a kyl)-amines