FI971674A0 - Di-tert-butylfenolföreningar med en heterocyklisk grupp användbara som antiinflammatoriska medel - Google Patents

Di-tert-butylfenolföreningar med en heterocyklisk grupp användbara som antiinflammatoriska medel

Info

Publication number
FI971674A0
FI971674A0 FI971674A FI971674A FI971674A0 FI 971674 A0 FI971674 A0 FI 971674A0 FI 971674 A FI971674 A FI 971674A FI 971674 A FI971674 A FI 971674A FI 971674 A0 FI971674 A0 FI 971674A0
Authority
FI
Finland
Prior art keywords
tert
useful
heterocyclic group
compounds containing
inflammatory agents
Prior art date
Application number
FI971674A
Other languages
English (en)
Finnish (fi)
Other versions
FI971674A (sv
Inventor
Michael Wiard Scherz
Stanislaw Pikul
Original Assignee
Procter & Gamble
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Procter & Gamble filed Critical Procter & Gamble
Publication of FI971674A0 publication Critical patent/FI971674A0/sv
Publication of FI971674A publication Critical patent/FI971674A/sv

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/06Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42Oxazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/06Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D231/08Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with oxygen or sulfur atoms directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D261/00Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/04Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
FI971674A 1994-10-20 1997-04-18 Di-tert-butylfenolföreningar med en heterocyklisk grupp användbara som antiinflammatoriska medel FI971674A (sv)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/326,619 US5510361A (en) 1994-10-20 1994-10-20 Di-tert-butylphenol compounds with heterocyclic moiety, useful as anti-inflammatory agents
PCT/US1995/012878 WO1996012710A1 (en) 1994-10-20 1995-10-18 Di-tert-butylphenol compounds with heterocyclic moiety, useful as anti-inflammatory agents

Publications (2)

Publication Number Publication Date
FI971674A0 true FI971674A0 (sv) 1997-04-18
FI971674A FI971674A (sv) 1997-04-18

Family

ID=23272988

Family Applications (1)

Application Number Title Priority Date Filing Date
FI971674A FI971674A (sv) 1994-10-20 1997-04-18 Di-tert-butylfenolföreningar med en heterocyklisk grupp användbara som antiinflammatoriska medel

Country Status (8)

Country Link
US (1) US5510361A (sv)
EP (1) EP0787130A1 (sv)
JP (1) JPH10507754A (sv)
KR (1) KR100226509B1 (sv)
AU (1) AU705645B2 (sv)
FI (1) FI971674A (sv)
NO (1) NO971789L (sv)
WO (1) WO1996012710A1 (sv)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
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DE4408084A1 (de) * 1994-03-10 1995-09-14 Hoechst Ag 3,5-Disubstituierte und 3,4,5-trisubstituierte 2-Isoxazoline und Isoxazole, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
JP3588734B2 (ja) * 1996-07-26 2004-11-17 コニカミノルタホールディングス株式会社 電子写真感光体
US5985930A (en) 1996-11-21 1999-11-16 Pasinetti; Giulio M. Treatment of neurodegenerative conditions with nimesulide
DE60234057D1 (de) 2001-07-25 2009-11-26 Raptor Pharmaceutical Inc Zusammensetzungen und verfahren zur modulation des transports durch die blut-hirn-schranke
CA2459125A1 (en) 2001-09-26 2003-04-03 Theravance, Inc. Substituted phenol compounds useful for anesthesia and sedation
US6555563B1 (en) 2001-11-16 2003-04-29 Medinox, Inc. Heteroaryl substituted amidinyl and imidazolyl compounds and methods employing same for the treatment of inflammation
US7479507B2 (en) * 2003-01-14 2009-01-20 Adam Heller Anti-inflammatory substituted phenols and elastomeric compositions for oral delivery of drugs
US20050003024A1 (en) * 2003-03-04 2005-01-06 The Procter & Gamble Company Regulation of mammalian hair growth
US20050255060A1 (en) * 2004-05-10 2005-11-17 Oblong John E Personal care compositions and methods regulating mammalian hair growth
US20050255059A1 (en) * 2004-05-10 2005-11-17 Oblong John E Personal care compositions and methods regulating mammalian hair growth
EP2392258B1 (en) 2005-04-28 2014-10-08 Proteus Digital Health, Inc. Pharma-informatics system
US20070203240A1 (en) * 2006-02-27 2007-08-30 The Procter & Gamble Company Personal care compositions and methods for regulating mammalian hair growth
US8795627B2 (en) 2007-03-21 2014-08-05 Raptor Pharmaceuticals Inc. Treatment of liver disorders by administration of RAP conjugates
AU2010216512B2 (en) 2009-02-20 2016-06-30 2-Bbb Medicines B.V. Glutathione-based drug delivery system
WO2010129819A2 (en) 2009-05-06 2010-11-11 Laboratory Skin Care, Inc. Dermal delivery compositions comprising active agent-calcium phosphate particle complexes and methods of using the same
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates
KR20150127172A (ko) 2013-03-14 2015-11-16 다트 뉴로사이언스 (케이만) 엘티디. Mao 억제제로서 치환된 나프티리딘 및 퀴놀린 화합물
US9550754B2 (en) 2014-09-11 2017-01-24 AbbVie Deutschland GmbH & Co. KG 4,5-dihydropyrazole derivatives, pharmaceutical compositions containing them, and their use in therapy

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4239901A (en) * 1976-10-14 1980-12-16 Byk Gulden Lomberg Chemische Fabrik Gmbh Pyrazol-1-ylphenylacetic acids
US4535165A (en) * 1981-11-23 1985-08-13 Riker Laboratories, Inc. Substituted diazoles and thiazoles
JPS58148858A (ja) * 1982-02-26 1983-09-05 Yamanouchi Pharmaceut Co Ltd 3,5−ジ−tert−ブチル−4−ヒドロキシフエニル置換複素環化合物
IE59813B1 (en) * 1986-05-09 1994-04-06 Warner Lambert Co Styryl pyrazoles, isoxazoles and analogs thereof having activity as 5-lipoxy-genase inhibitors and pharmaceutical compositions containing them
JPH0615542B2 (ja) * 1986-07-22 1994-03-02 吉富製薬株式会社 ピラゾロピリジン化合物
US4724246A (en) * 1986-12-10 1988-02-09 Ciba-Geigy Corporation Substituted 1,3,4-oxathiazol-2-one stabilizers
DE3702758A1 (de) * 1987-01-30 1988-09-29 Hoechst Ag Substituierte 3-phenyl-7h-thiazolo (3,2-b) (1,2,4) triazin-7-one, verfahren zu ihrer herstellung, die sie enthaltenden arzneimittel und ihre verwendung, sowie einige bei der herstellung der genannten verbindungen gebildete zwischenprodukte
DE3702757A1 (de) * 1987-01-30 1988-08-11 Hoechst Ag Neue imidazo- und triazolo-thiadiazine, verfahren zu ihrer herstellung, die sie enthaltenden arzneimittel und ihre verwendung, sowie einige bei der herstellung der genannten verbindungen gebildete zwischenprodukte
DE3702756A1 (de) * 1987-01-30 1988-08-11 Hoechst Ag 5-(3-alkyl-5-tert.butyl-4-hydroxyphenyl)-2- amino-6h-1,3,4-thiadiazine, verfahren zu ihrer herstellung, die sie enthaltenden arzneimittel und ihre verwendung
JPH01180878A (ja) * 1988-01-11 1989-07-18 Yoshitomi Pharmaceut Ind Ltd 縮合ピラゾール化合物
US5155122A (en) * 1988-11-29 1992-10-13 Warner-Lambert Company 3,5-di-tertiary-butyl-4-hydroxyphenyl-1,3,4-thiadiazoles, and oxadiazoles and 3,5-di-tertiary-butyl-4-hydroxy-phenyl-1,2,4-thiadazoles, oxadiazoles and triazoles as antiinflammatory agents
JPH02229169A (ja) * 1989-03-01 1990-09-11 Takeda Chem Ind Ltd ピラゾロン誘導体
DE3918979A1 (de) * 1989-06-10 1990-12-13 Basf Ag Verfahren zur herstellung von pyrazol und dessen derivaten
DE4408084A1 (de) * 1994-03-10 1995-09-14 Hoechst Ag 3,5-Disubstituierte und 3,4,5-trisubstituierte 2-Isoxazoline und Isoxazole, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel

Also Published As

Publication number Publication date
EP0787130A1 (en) 1997-08-06
AU3859895A (en) 1996-05-15
KR970707108A (ko) 1997-12-01
MX9702941A (es) 1997-07-31
FI971674A (sv) 1997-04-18
AU705645B2 (en) 1999-05-27
KR100226509B1 (ko) 1999-10-15
US5510361A (en) 1996-04-23
WO1996012710A1 (en) 1996-05-02
NO971789L (no) 1997-06-19
JPH10507754A (ja) 1998-07-28
NO971789D0 (no) 1997-04-18

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