FI971151A - Kolesterolin absorption inhibiittorin ja kolesterolin synteesin inhibiittorin yhdistelmä - Google Patents

Kolesterolin absorption inhibiittorin ja kolesterolin synteesin inhibiittorin yhdistelmä Download PDF

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Publication number
FI971151A
FI971151A FI971151A FI971151A FI971151A FI 971151 A FI971151 A FI 971151A FI 971151 A FI971151 A FI 971151A FI 971151 A FI971151 A FI 971151A FI 971151 A FI971151 A FI 971151A
Authority
FI
Finland
Prior art keywords
cholesterol
inhibitor
combination
cholesterol absorption
synthesis inhibitor
Prior art date
Application number
FI971151A
Other languages
English (en)
Swedish (sv)
Other versions
FI971151A0 (fi
Inventor
Lee A Morehouse
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of FI971151A publication Critical patent/FI971151A/fi
Publication of FI971151A0 publication Critical patent/FI971151A0/fi

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
FI971151A 1994-09-20 1997-03-19 Kolesterolin absorption inhibiittorin ja kolesterolin synteesin inhibiittorin yhdistelmä FI971151A0 (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US30890894A 1994-09-20 1994-09-20
PCT/IB1995/000447 WO1996009827A2 (en) 1994-09-20 1995-06-07 Combination of a cholesterol absorption inhibitor and a cholesterol synthesis inhibitor

Publications (2)

Publication Number Publication Date
FI971151A true FI971151A (fi) 1997-03-19
FI971151A0 FI971151A0 (fi) 1997-03-19

Family

ID=23195885

Family Applications (1)

Application Number Title Priority Date Filing Date
FI971151A FI971151A0 (fi) 1994-09-20 1997-03-19 Kolesterolin absorption inhibiittorin ja kolesterolin synteesin inhibiittorin yhdistelmä

Country Status (12)

Country Link
US (1) US5807834A (fi)
EP (1) EP0782451A1 (fi)
JP (1) JPH09511753A (fi)
AU (1) AU2453295A (fi)
BR (1) BR9504072A (fi)
CA (1) CA2200436A1 (fi)
FI (1) FI971151A0 (fi)
HR (1) HRP950488A2 (fi)
IL (1) IL115310A0 (fi)
MX (1) MX9702175A (fi)
WO (1) WO1996009827A2 (fi)
ZA (1) ZA957879B (fi)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0737202A1 (en) * 1993-12-28 1996-10-16 Pfizer Inc. Hypocholesterolemic agents
BR9505995A (pt) * 1994-12-23 1997-12-23 Pfizer Composto método para tratamentos e composição farmacêutica
AU2401697A (en) * 1996-06-20 1998-01-07 Pfizer Inc. 4,1-benzoxazepines or 4,1-benzothiazepines and their use as squalene synthetase inhibitors
US5965553A (en) * 1996-06-20 1999-10-12 Pfizer Inc. Squalene synthetase inhibitors
WO1998047882A1 (en) 1997-04-21 1998-10-29 Takeda Chemical Industries, Ltd. 4,1-benzoxazepines, their analogues, and their use as somatostatin agonists
US6180660B1 (en) * 1997-08-26 2001-01-30 Merck & Co., Inc. Cholesterol-lowering therapy
US20030153541A1 (en) * 1997-10-31 2003-08-14 Robert Dudley Novel anticholesterol compositions and method for using same
GB9923076D0 (en) * 1999-09-29 1999-12-01 Phytopharm Plc Sapogenin derivatives and their use
DE69929177T2 (de) * 1998-03-26 2006-08-24 Phytopharm Plc, Godmanchester Smilagenin und anzurogenin-d zur behandlung der alzheimerischen krankheit
US6207664B1 (en) 1998-11-25 2001-03-27 Pfizer Inc. Squalene synthetase inhibitor agents
GB9923078D0 (en) * 1999-09-29 1999-12-01 Phytopharm Plc Sapogenin derivatives and their use
US6465011B2 (en) 1999-05-29 2002-10-15 Abbott Laboratories Formulations comprising lipid-regulating agents
US6372251B2 (en) 1999-06-11 2002-04-16 Abbott Laboratories Formulations comprising lipid-regulating agents
GB9923077D0 (en) * 1999-09-29 1999-12-01 Phytopharm Plc Sapogenin derivatives and their use
GB0000228D0 (en) * 2000-01-06 2000-03-01 Phytopharm Plc Fluoro substituted sapogenins and their use
US20030092745A1 (en) * 2000-02-25 2003-05-15 Pfizer Inc. Combination therapy
GB0107822D0 (en) * 2001-03-28 2001-05-23 Phytopharm Plc Sapogenin derivatives their synthesis and use methods based upon their use
CN102727501A (zh) * 2002-03-27 2012-10-17 菲特法姆股份有限公司 皂角苷配基及其衍生物的用途
US20050130948A1 (en) * 2002-03-27 2005-06-16 Daryl Rees Therapeutic methods and uses of sapogenins and their derivatives
GB0215579D0 (en) 2002-07-05 2002-08-14 Astrazeneca Ab Chemical compounds
AR040588A1 (es) * 2002-07-26 2005-04-13 Schering Corp Formulacion farmaceutica que comprende un inhibidor de la absorcion del colesterol y un inhibidor de una hmg- co a reductasa
KR101092150B1 (ko) * 2002-10-28 2011-12-12 파이토팜 피엘씨 사포겐-3-온의 입체특이적 환원
ES2311806T3 (es) 2003-03-07 2009-02-16 Schering Corporation Compuesto de azetidinona sustituidos, fornulaciones y usos de los mismos para el tratamiento de hipercolesterolemia.
EP1601669B1 (en) 2003-03-07 2008-12-24 Schering Corporation Substituted azetidinone compounds, formulations and uses thereof for the treatment of hypercholesterolemia
WO2005051298A2 (en) 2003-11-19 2005-06-09 Metabasis Therapeutics, Inc. Novel phosphorus-containing thyromimetics
US7871998B2 (en) 2003-12-23 2011-01-18 Astrazeneca Ab Diphenylazetidinone derivatives possessing cholesterol absorption inhibitory activity
JP4477474B2 (ja) * 2004-11-15 2010-06-09 株式会社日立製作所 糞便懸濁ろ過用容器
SA06270191B1 (ar) 2005-06-22 2010-03-29 استرازينيكا ايه بي مشتقات من 2- أزيتيدينون جديدة باعتبارها مثبطات لامتصاص الكوليسترول لعلاج حالات فرط نسبة الدهون في الدم
BRPI0617621A2 (pt) 2005-10-21 2011-08-02 Novartis Ag combinação de compostos orgánicos
AR060623A1 (es) 2006-04-27 2008-07-02 Astrazeneca Ab Compuestos derivados de 2-azetidinona y un metodo de preparacion
WO2010021681A2 (en) * 2008-08-18 2010-02-25 Combinatorx (Singapore) Pte. Ltd. Compositions and methods for treatment of viral diseases
US20120046364A1 (en) 2009-02-10 2012-02-23 Metabasis Therapeutics, Inc. Novel Sulfonic Acid-Containing Thyromimetics, and Methods for Their Use
US20130156720A1 (en) 2010-08-27 2013-06-20 Ironwood Pharmaceuticals, Inc. Compositions and methods for treating or preventing metabolic syndrome and related diseases and disorders

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4602005A (en) * 1982-05-17 1986-07-22 Medical Research Foundation Of Oregon Tigogenin cellobioside for treating hypercholesterolemia and atherosclerosis
US5063210A (en) * 1989-04-20 1991-11-05 Lange Iii Louis G Use of sulfated polysaccharides to decrease cholesterol and fatty acid absorption
WO1994000480A1 (en) * 1992-06-26 1994-01-06 Pfizer Inc. Steroidal glycosides for treating hypercholesterolemia
LT3300B (en) * 1992-12-23 1995-06-26 Schering Corp Combination of a cholesterol biosynhtesis inhibitor and a beta- lactam cholesterol absorbtion inhibitor

Also Published As

Publication number Publication date
MX9702175A (es) 1997-06-28
WO1996009827A3 (en) 1996-05-23
JPH09511753A (ja) 1997-11-25
AU2453295A (en) 1996-04-19
ZA957879B (en) 1997-03-19
EP0782451A1 (en) 1997-07-09
WO1996009827A2 (en) 1996-04-04
BR9504072A (pt) 1996-07-30
US5807834A (en) 1998-09-15
FI971151A0 (fi) 1997-03-19
HRP950488A2 (en) 1997-08-31
IL115310A0 (en) 1995-12-31
CA2200436A1 (en) 1996-04-04

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