FI962377A0 - Humaniserade antikroppar och användning av dessa - Google Patents

Humaniserade antikroppar och användning av dessa

Info

Publication number
FI962377A0
FI962377A0 FI962377A FI962377A FI962377A0 FI 962377 A0 FI962377 A0 FI 962377A0 FI 962377 A FI962377 A FI 962377A FI 962377 A FI962377 A FI 962377A FI 962377 A0 FI962377 A0 FI 962377A0
Authority
FI
Finland
Prior art keywords
humanized antibodies
humanized
antibodies
Prior art date
Application number
FI962377A
Other languages
English (en)
Finnish (fi)
Other versions
FI962377A (sv
Inventor
Augustine Yee-Tharn Lin
Original Assignee
T Cell Sciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by T Cell Sciences Inc filed Critical T Cell Sciences Inc
Publication of FI962377A0 publication Critical patent/FI962377A0/sv
Publication of FI962377A publication Critical patent/FI962377A/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2809—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against the T-cell receptor (TcR)-CD3 complex
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Animal Behavior & Ethology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
FI962377A 1993-12-08 1996-06-07 Humaniserade antikroppar och användning av dessa FI962377A (sv)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB939325182A GB9325182D0 (en) 1993-12-08 1993-12-08 Humanized antibodies or binding proteins thereof specific for t cell subpopulations exhibiting select beta chain variable regions
PCT/IB1994/000387 WO1995016038A2 (en) 1993-12-08 1994-11-21 Humanized antibodies and uses thereof

Publications (2)

Publication Number Publication Date
FI962377A0 true FI962377A0 (sv) 1996-06-07
FI962377A FI962377A (sv) 1996-07-30

Family

ID=10746330

Family Applications (1)

Application Number Title Priority Date Filing Date
FI962377A FI962377A (sv) 1993-12-08 1996-06-07 Humaniserade antikroppar och användning av dessa

Country Status (24)

Country Link
US (1) US5861155A (sv)
EP (1) EP0737250A1 (sv)
JP (1) JPH09509307A (sv)
KR (2) KR100239607B1 (sv)
CN (1) CN1063792C (sv)
AU (1) AU699249B2 (sv)
BR (1) BR9408278A (sv)
CA (1) CA2178622A1 (sv)
CZ (2) CZ287347B6 (sv)
EE (1) EE03271B1 (sv)
FI (1) FI962377A (sv)
GB (1) GB9325182D0 (sv)
HU (1) HUT75553A (sv)
IL (1) IL111926A (sv)
LV (1) LV11631B (sv)
NO (1) NO962346L (sv)
NZ (1) NZ276170A (sv)
PL (1) PL180157B1 (sv)
RU (1) RU2139934C1 (sv)
SG (1) SG48420A1 (sv)
SK (1) SK73596A3 (sv)
UA (1) UA29494C2 (sv)
WO (1) WO1995016038A2 (sv)
ZA (1) ZA949341B (sv)

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CN1064052C (zh) * 1997-09-29 2001-04-04 中国科学院微生物研究所 甲状旁腺素相关蛋白人源化抗体及其制备方法
AU2444899A (en) * 1998-01-22 1999-08-09 Astrazeneca Ab Pharmaceutical formulation comprising an antibody and a citrate buffer
GB9906233D0 (en) * 1999-03-19 1999-05-12 Univ Newcastle Bone formation
EP1326991A2 (en) * 2000-10-20 2003-07-16 Whitehead Institute For Biomedical Research Expression vectors and uses thereof
AU2003221118A1 (en) * 2002-03-22 2003-10-08 Bipha Corporation Immunoglobulin/hydrophilic peptide complexes
US7794716B2 (en) 2002-07-25 2010-09-14 Glenveigh Pharmaceuticals, Llc Antibody composition and passive immunization against pregnancy-induced hypertension
GB0302740D0 (en) * 2003-02-06 2003-03-12 Axis Shield Asa Assay
US7794713B2 (en) * 2004-04-07 2010-09-14 Lpath, Inc. Compositions and methods for the treatment and prevention of hyperproliferative diseases
PT1742966E (pt) * 2004-04-22 2014-02-05 Agensys Inc Anticorpos e moléculas derivadas daí que se ligam às proteínas steap-1
EP1921137A4 (en) * 2005-06-21 2011-01-26 Med & Biological Lab Co Ltd ANTIBODIES WITH INHIBITOR EFFECT ON THE FORMATION OF AMYLOID FIBRILLES
KR100740201B1 (ko) * 2005-10-21 2007-07-18 삼성전자주식회사 듀얼 전송 스트림 생성 장치 및 그 방법
US20090074720A1 (en) * 2005-10-28 2009-03-19 Sabbadini Roger A Methods for decreasing immune response and treating immune conditions
US20080213274A1 (en) * 2005-10-28 2008-09-04 Sabbadini Roger A Compositions and methods for the treatment and prevention of fibrotic, inflammatory, and neovascularization conditions of the eye
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US7862812B2 (en) * 2006-05-31 2011-01-04 Lpath, Inc. Methods for decreasing immune response and treating immune conditions
AU2007269714A1 (en) 2006-07-03 2008-01-10 Charles David Adair Composition for modulating the expression of cell adhesion molecules
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JP5732182B2 (ja) * 2006-10-27 2015-06-10 エルパス・インコーポレイテッドＬｐａｔｈ， Ｉｎｃ． 眼疾患と症状を処置するための組成物および方法
US8604172B2 (en) * 2009-04-17 2013-12-10 Lpath, Inc. Humanized antibody compositions and methods for binding lysophosphatidic acid
US9163091B2 (en) * 2007-05-30 2015-10-20 Lpath, Inc. Compositions and methods for binding lysophosphatidic acid
US8158124B2 (en) * 2007-05-30 2012-04-17 Lpath, Inc. Compositions and methods for binding lysophosphatidic acid
US20110064744A1 (en) * 2007-05-30 2011-03-17 Sabbadini Roger A Prevention and treatment of pain using antibodies to lysophosphatidic acid
JP2010535503A (ja) 2007-08-10 2010-11-25 エージェンシー フォー サイエンス，テクノロジー アンド リサーチ（エー＊エスティーエーアール） 癌の診断および治療のためのｖｈｚ
US7867497B2 (en) * 2007-09-24 2011-01-11 Vanderbilt University Monoclonal antibodies to respiratory syncytial virus and uses therefor
US8361465B2 (en) * 2007-10-26 2013-01-29 Lpath, Inc. Use of anti-sphingosine-1-phosphate antibodies in combination with chemotherapeutic agents
JP5756014B2 (ja) * 2008-08-08 2015-07-29 エイジェンシー・フォー・サイエンス，テクノロジー・アンド・リサーチ（エイ・スター） がんの診断および治療のためのｖｈｚ
US8871202B2 (en) 2008-10-24 2014-10-28 Lpath, Inc. Prevention and treatment of pain using antibodies to sphingosine-1-phosphate
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US8401799B2 (en) * 2008-12-05 2013-03-19 Lpath, Inc. Antibody design using anti-lipid antibody crystal structures
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US8859736B2 (en) 2010-02-19 2014-10-14 The Board Of Regents Of The University Of Oklahoma Monoclonal antibodies that inhibit the wnt signaling pathway and methods of production and use thereof
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PT2663579T (pt) 2011-01-14 2017-07-28 Univ California Terapêutica de anticorpos contra a proteína r0r-1 e métodos para sua utilização
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US11253590B2 (en) 2015-12-02 2022-02-22 Stsciences, Inc. Antibodies specific to glycosylated BTLA (B- and T- lymphocyte attenuator)
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AU2017224122B2 (en) 2016-02-26 2024-04-11 The Board Of Regents Of The University Of Texas System Connexin (Cx) 43 hemichannel-binding antibodies and uses thereof
CN109462996A (zh) 2016-03-17 2019-03-12 西达-赛奈医疗中心 通过rnaset2诊断炎性肠病的方法
KR102418372B1 (ko) 2016-03-29 2022-07-08 주식회사 에스티큐브 글리코실화된 pd-l1에 특이적인 이중 기능 항체 및 이의 사용 방법
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Also Published As

Publication number Publication date
PL180157B1 (en) 2000-12-29
KR960706560A (ko) 1996-12-09
SK73596A3 (en) 1997-05-07
PL314908A1 (en) 1996-09-30
ZA949341B (en) 1996-05-24
UA29494C2 (uk) 2000-11-15
GB9325182D0 (en) 1994-02-09
WO1995016038A2 (en) 1995-06-15
CA2178622A1 (en) 1995-06-15
LV11631A (lv) 1996-12-20
LV11631B (en) 1997-04-20
IL111926A0 (en) 1995-03-15
HU9601574D0 (en) 1996-07-29
KR100258902B1 (en) 2000-06-15
CN1142855A (zh) 1997-02-12
EE03271B1 (et) 2000-06-15
HUT75553A (en) 1997-05-28
CN1063792C (zh) 2001-03-28
CZ162896A3 (en) 1997-01-15
RU2139934C1 (ru) 1999-10-20
CZ287298B6 (cs) 2000-10-11
EP0737250A1 (en) 1996-10-16
IL111926A (en) 2002-07-25
SG48420A1 (en) 1998-04-17
JPH09509307A (ja) 1997-09-22
FI962377A (sv) 1996-07-30
CZ287347B6 (en) 2000-10-11
US5861155A (en) 1999-01-19
NO962346D0 (no) 1996-06-05
AU699249B2 (en) 1998-11-26
NZ276170A (en) 1998-05-27
NO962346L (no) 1996-08-06
AU1033395A (en) 1995-06-27
WO1995016038A3 (en) 1995-07-06
KR100239607B1 (ko) 2000-01-15
BR9408278A (pt) 1996-12-17

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