FI961544A - Hapetetut karotenoidit, retinoidit ja lähisukuiset konjugoidut polyeenit sekä johdetut jakeet ja yhdisteet, jotka ovat hyödyllisiä solujen erilaistumista indusoivina aineina, sytostaattisina aineina ja kasvaimien vastaisina aineina - Google Patents

Hapetetut karotenoidit, retinoidit ja lähisukuiset konjugoidut polyeenit sekä johdetut jakeet ja yhdisteet, jotka ovat hyödyllisiä solujen erilaistumista indusoivina aineina, sytostaattisina aineina ja kasvaimien vastaisina aineina Download PDF

Info

Publication number
FI961544A
FI961544A FI961544A FI961544A FI961544A FI 961544 A FI961544 A FI 961544A FI 961544 A FI961544 A FI 961544A FI 961544 A FI961544 A FI 961544A FI 961544 A FI961544 A FI 961544A
Authority
FI
Finland
Prior art keywords
carotene
vitamin
oxidized
beta
useful
Prior art date
Application number
FI961544A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI961544A0 (fi
Inventor
Graham Burton
Janusz Daroszewski
Jenny Phipps
Prabhat Arya
Original Assignee
Ca Nat Research Council
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ca Nat Research Council filed Critical Ca Nat Research Council
Publication of FI961544A publication Critical patent/FI961544A/fi
Publication of FI961544A0 publication Critical patent/FI961544A0/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/27—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation
    • C07C45/28—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by oxidation of CHx-moieties
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06139—Dipeptides with the first amino acid being heterocyclic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C403/00—Derivatives of cyclohexane or of a cyclohexene or of cyclohexadiene, having a side-chain containing an acyclic unsaturated part of at least four carbon atoms, this part being directly attached to the cyclohexane or cyclohexene or cyclohexadiene rings, e.g. vitamin A, beta-carotene, beta-ionone

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Nutrition Science (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Compounds Of Unknown Constitution (AREA)
FI961544A 1994-08-10 1996-04-09 Hapetetut karotenoidit, retinoidit ja lähisukuiset konjugoidut polyeenit sekä johdetut jakeet ja yhdisteet, jotka ovat hyödyllisiä solujen erilaistumista indusoivina aineina, sytostaattisina aineina ja kasvaimien vastaisina aineina FI961544A0 (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/288,315 US5475006A (en) 1994-08-10 1994-08-10 Extensively oxidized derivatives of carotenoids, retinoids and related conjugated polyenes useful as non-toxic cell-differentiation inducers, anti-proliferative agents, and anti-tumor agents
PCT/CA1995/000484 WO1996005160A1 (en) 1994-08-10 1995-08-10 Oxidized carotenoids, retinoids and related conjugated polyenes, and derived fractions and compounds useful as cell-differentiation inducers, cytostatic agents, and anti-tumor agents

Publications (2)

Publication Number Publication Date
FI961544A true FI961544A (fi) 1996-04-09
FI961544A0 FI961544A0 (fi) 1996-04-09

Family

ID=23106590

Family Applications (1)

Application Number Title Priority Date Filing Date
FI961544A FI961544A0 (fi) 1994-08-10 1996-04-09 Hapetetut karotenoidit, retinoidit ja lähisukuiset konjugoidut polyeenit sekä johdetut jakeet ja yhdisteet, jotka ovat hyödyllisiä solujen erilaistumista indusoivina aineina, sytostaattisina aineina ja kasvaimien vastaisina aineina

Country Status (19)

Country Link
US (1) US5475006A (ko)
EP (1) EP0722431B1 (ko)
JP (1) JP3983800B2 (ko)
KR (1) KR100404724B1 (ko)
CN (1) CN1131939A (ko)
AT (1) ATE201394T1 (ko)
AU (1) AU704640B2 (ko)
CA (1) CA2171625C (ko)
CZ (1) CZ103896A3 (ko)
DE (1) DE69521020T2 (ko)
ES (1) ES2160172T3 (ko)
FI (1) FI961544A0 (ko)
GB (1) GB2297325B (ko)
HK (1) HK1013814A1 (ko)
MX (1) MX9601175A (ko)
NZ (1) NZ290769A (ko)
PL (1) PL184296B1 (ko)
PT (1) PT722431E (ko)
WO (1) WO1996005160A1 (ko)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6432711B1 (en) * 1993-11-03 2002-08-13 Diacrin, Inc. Embryonic stem cells capable of differentiating into desired cell lines
US7132458B2 (en) * 1994-08-10 2006-11-07 Chemaphor Inc. Oxidized carotenoid fractions and ketoaldehyde useful as cell-differentiation inducers, cytostatic agents, and anti-tumor agents
US20040228871A1 (en) * 1999-06-03 2004-11-18 Tayyaba Hasan Treatment and analysis of proliferative disorders
IL135335A (en) * 2000-03-29 2013-12-31 Lycored Natural Prod Ind Ltd Use of Carotenoids in Preparing Pharmaceuticals to Prevent Adverse Effects from Hormones and Pharmaceuticals Containing Carotenoids
US20020031539A1 (en) * 2000-08-30 2002-03-14 The Brigham And Women's Hospital, Inc. Oxidized forms of retinoic acid as ligands for peroxisome proliferator activated receptor gamma
US20050037048A1 (en) * 2003-08-11 2005-02-17 Young-Ho Song Medical devices containing antioxidant and therapeutic agent
US20050064011A1 (en) * 2003-08-11 2005-03-24 Young-Ho Song Implantable or insertable medical devices containing phenolic compound for inhibition of restenosis
US20080025929A1 (en) * 2004-02-19 2008-01-31 Chemaphor, Inc. Topical Formulations for the Treatment of Skin Conditions
CN101065024A (zh) 2004-09-28 2007-10-31 凯马福尔公司 促进增重和饲料转化的组合物和方法
US20090069417A1 (en) * 2005-10-11 2009-03-12 Yoav Sharoni Carotenoid oxidation products as chemopreventive and chemotherapeutic agents
AU2007234338A1 (en) * 2006-04-05 2007-10-11 Chemaphor Inc. Carotenoid-containing dietary supplement
CN101970012A (zh) 2007-09-14 2011-02-09 日东电工株式会社 药物载体
JP2011500733A (ja) * 2007-10-26 2011-01-06 ケマファー インコーポレーテッド 免疫応答を増強するための組成物および方法
AU2010242502B2 (en) 2009-04-30 2016-11-10 Avivagen Inc. Methods and compositions for improving the health of animals
EP3288546B1 (en) * 2015-04-28 2021-12-15 Avivagen Inc. Oxidized carotenoids and components thereof for preventing necrotic enteritis
CN107847761B (zh) * 2015-08-20 2021-06-04 I.B.R.以色列生物科技研究有限公司 具有抗病毒活性的类胡萝卜素组合物及其用途
US20190054135A1 (en) * 2016-02-25 2019-02-21 Avivagen Inc. Plant or microorganism-derived carotenoid-oxygen copolymer compositions, methods of identifying, quantifying and producing same and uses thereof
CN106614301A (zh) * 2016-11-14 2017-05-10 鄂尔多斯市绿食保山羊食品有限公司 山羊的有机养殖方法
KR102683182B1 (ko) * 2021-11-12 2024-07-11 주식회사 에이펙셀 메타 아르세나이트 염을 포함하는 암 치료용 약학 조성물

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2505869C3 (de) * 1975-02-12 1978-05-18 Basf Ag, 6700 Ludwigshafen Verfahren zur Herstellung von symmetrischen Carotinoiden
DE2635802C2 (de) * 1976-08-09 1984-03-01 Basf Ag, 6700 Ludwigshafen Verfahren zur Herstellung von symmetrischen Carotinoiden
DK595489D0 (da) * 1989-11-27 1989-11-27 Neurosearch As Hydroxycarbonylderivater og fremgangsmaade til fremstilling af samme
US5225604A (en) * 1989-11-27 1993-07-06 Neurosearch A/S Hydroxycarbonyl derivatives and process for making the same
US5310554A (en) * 1992-10-27 1994-05-10 Natural Carotene Corporation High purity beta-carotene
US5358915A (en) * 1993-02-12 1994-10-25 American Colloid Company Process for regenerating spent acid-activated bentonite clays and smectite catalysts

Also Published As

Publication number Publication date
KR960704828A (ko) 1996-10-09
HK1013814A1 (en) 1999-09-10
AU3160095A (en) 1996-03-07
AU704640B2 (en) 1999-04-29
EP0722431A1 (en) 1996-07-24
NZ290769A (en) 1998-08-26
CA2171625C (en) 2008-10-14
PL313907A1 (en) 1996-08-05
DE69521020T2 (de) 2001-11-15
FI961544A0 (fi) 1996-04-09
EP0722431B1 (en) 2001-05-23
CZ103896A3 (en) 1996-11-13
GB2297325A (en) 1996-07-31
CA2171625A1 (en) 1996-02-22
CN1131939A (zh) 1996-09-25
GB9604444D0 (en) 1996-05-01
ES2160172T3 (es) 2001-11-01
MX9601175A (es) 1997-06-28
GB2297325B (en) 1999-01-13
ATE201394T1 (de) 2001-06-15
US5475006A (en) 1995-12-12
PL184296B1 (pl) 2002-09-30
JP3983800B2 (ja) 2007-09-26
KR100404724B1 (ko) 2004-04-03
DE69521020D1 (de) 2001-06-28
PT722431E (pt) 2001-11-30
WO1996005160A1 (en) 1996-02-22
JPH09504038A (ja) 1997-04-22

Similar Documents

Publication Publication Date Title
FI961544A (fi) Hapetetut karotenoidit, retinoidit ja lähisukuiset konjugoidut polyeenit sekä johdetut jakeet ja yhdisteet, jotka ovat hyödyllisiä solujen erilaistumista indusoivina aineina, sytostaattisina aineina ja kasvaimien vastaisina aineina
Blumberg Considerations of the scientific substantiation for antioxidant vitamins and beta-carotene in disease prevention
Ribeiro et al. Antioxidant and pro-oxidant activities of carotenoids and their oxidation products
Omaye et al. β-Carotene: friend or foe?
Gradelet et al. β-Apo-8′-carotenal, but not β-carotene, is a strong inducer of liver cytochromes P4501A1 and 1A2 in rat
Astorg Food carotenoids and cancer prevention: an overview of current research
Pryor et al. Beta carotene: from biochemistry to clinical trials
Paiva et al. β-carotene and other carotenoids as antioxidants
Skaper et al. Quercetin protects cutaneous tissue-associated cell types including sensory neurons from oxidative stress induced by glutathione depletion: cooperative effects of ascorbic acid
dela Seña et al. Substrate specificity of purified recombinant human β-carotene 15, 15′-oxygenase (BCO1)
Nara et al. Acyclic carotenoids and their oxidation mixtures inhibit the growth of HL-60 human promyelocytic leukemia cells
Palozza et al. Prooxidant effects of β-carotene in cultured cells
Gerster The potential role of lycopene for human health.
Riccioni Carotenoids and cardiovascular disease
Bendich Symposium conclusions: biological actions of carotenoids
ATE254903T1 (de) Eine phytoen und phytofluen enthaltende carotenoide zubereitung
Hix et al. Upregulation of connexin 43 protein expression and increased gap junctional communication by water soluble disodium disuccinate astaxanthin derivatives
Murayama et al. Photoisomerization of retinoic acids in ethanol under room light: a warning for cell biological study of geometrical isomers of retinoids
JP2014240441A (ja) アスタキサンチン含有加齢臭抑制組成物
Maoka et al. Antioxidative activity of capsorubin and related compounds from paprika (Capsicum annuum)
Deming et al. Carotenoids: Linking chemistry, absorption, and metabolism to potential roles in human health and disease
Wang et al. The bioconversion of β-carotene into retinoids
Casaril et al. Evaluation of the toxicity of α-(phenylselanyl) acetophenone in mice
ES2141978T3 (es) Retinoides triciclicos, metodos para su produccion y uso.
Scheer et al. Chemoprevention of oral squamous cell carcinomas