FI955727A - Förfarande och anordning för framställning av liposomer - Google Patents

Förfarande och anordning för framställning av liposomer Download PDF

Info

Publication number
FI955727A
FI955727A FI955727A FI955727A FI955727A FI 955727 A FI955727 A FI 955727A FI 955727 A FI955727 A FI 955727A FI 955727 A FI955727 A FI 955727A FI 955727 A FI955727 A FI 955727A
Authority
FI
Finland
Prior art keywords
critical
liposomes
supercritical
producing liposomes
methods
Prior art date
Application number
FI955727A
Other languages
English (en)
Finnish (fi)
Other versions
FI955727A0 (sv
FI115115B (sv
Inventor
Trevor P Castor
Original Assignee
Aphios Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aphios Corp filed Critical Aphios Corp
Publication of FI955727A0 publication Critical patent/FI955727A0/sv
Publication of FI955727A publication Critical patent/FI955727A/sv
Application granted granted Critical
Publication of FI115115B publication Critical patent/FI115115B/sv

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A61K9/1277—Processes for preparing; Proliposomes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Saccharide Compounds (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FI955727A 1993-05-28 1995-11-28 Förfarande och anordning för framställning av liposomer FI115115B (sv)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US08/069,134 US5554382A (en) 1993-05-28 1993-05-28 Methods and apparatus for making liposomes
US6913493 1993-05-28
PCT/US1994/005933 WO1994027581A1 (en) 1993-05-28 1994-05-26 Methods and apparatus for making liposomes
US9405933 1994-05-26

Publications (3)

Publication Number Publication Date
FI955727A0 FI955727A0 (sv) 1995-11-28
FI955727A true FI955727A (sv) 1996-01-26
FI115115B FI115115B (sv) 2005-03-15

Family

ID=22086969

Family Applications (1)

Application Number Title Priority Date Filing Date
FI955727A FI115115B (sv) 1993-05-28 1995-11-28 Förfarande och anordning för framställning av liposomer

Country Status (11)

Country Link
US (1) US5554382A (sv)
EP (1) EP0703778B1 (sv)
JP (1) JP3742427B2 (sv)
KR (1) KR960702748A (sv)
AT (1) ATE152615T1 (sv)
AU (1) AU6919094A (sv)
CA (1) CA2163903A1 (sv)
DE (1) DE69403077T2 (sv)
FI (1) FI115115B (sv)
NO (1) NO954756L (sv)
WO (1) WO1994027581A1 (sv)

Families Citing this family (78)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6509006B1 (en) 1992-07-08 2003-01-21 Inhale Therapeutic Systems, Inc. Devices compositions and methods for the pulmonary delivery of aerosolized medicaments
US6582728B1 (en) * 1992-07-08 2003-06-24 Inhale Therapeutic Systems, Inc. Spray drying of macromolecules to produce inhaleable dry powders
DE69528062T2 (de) * 1994-06-20 2003-04-30 Nippon Shinyaku Co., Ltd. Verfahren zum herstellen von emulsionen aus einem emulgator
GB9413202D0 (en) * 1994-06-30 1994-08-24 Univ Bradford Method and apparatus for the formation of particles
US6290991B1 (en) 1994-12-02 2001-09-18 Quandrant Holdings Cambridge Limited Solid dose delivery vehicle and methods of making same
WO1996015774A1 (en) * 1994-11-18 1996-05-30 Aphios Corporation Methods and apparatus for making liposomes containing hydrophobic drugs
DE4445341A1 (de) * 1994-12-19 1996-06-20 Basf Ag Verfahren und Vorrichtung zur Herstellung wirkstoffhaltiger Dispersionen
US5795587A (en) 1995-01-23 1998-08-18 University Of Pittsburgh Stable lipid-comprising drug delivery complexes and methods for their production
US6008202A (en) * 1995-01-23 1999-12-28 University Of Pittsburgh Stable lipid-comprising drug delivery complexes and methods for their production
GB9703673D0 (en) * 1997-02-21 1997-04-09 Bradford Particle Design Ltd Method and apparatus for the formation of particles
NZ503293A (en) * 1997-09-16 2002-09-27 Nexstar Pharmaceuticals Inc Liposomal camptothecin formulations also comprising at least one phospholipid
US6740335B1 (en) * 1997-09-16 2004-05-25 Osi Pharmaceuticals, Inc. Liposomal camptothecin formulations
CA2304096C (en) 1997-09-18 2003-09-09 Skyepharma Inc. Sustained-release liposomal anesthetic compositions
NZ504188A (en) 1997-11-14 2001-10-26 Skyepharma Inc Emulsification process for preparing multivesicular liposomes
US5994855A (en) 1998-05-07 1999-11-30 Optiva Corporation Automatic power adjustment system for introductory use of a vibrating device on a human body
GB9810559D0 (en) * 1998-05-15 1998-07-15 Bradford Particle Design Ltd Method and apparatus for particle formation
US7314637B1 (en) 1999-06-29 2008-01-01 Neopharm, Inc. Method of administering liposomal encapsulated taxane
US6461637B1 (en) * 2000-09-01 2002-10-08 Neopharm, Inc. Method of administering liposomal encapsulated taxane
CA2350430C (en) * 1998-11-13 2008-06-03 Optime Therapeutics, Inc. Method and apparatus for liposome production
US6855296B1 (en) 1998-11-13 2005-02-15 Optime Therapeutics, Inc. Method and apparatus for liposome production
US6040330A (en) * 1999-01-08 2000-03-21 Bionumerik Pharmaceuticals, Inc. Pharmaceutical formulations of taxanes
GB9915975D0 (en) 1999-07-07 1999-09-08 Bradford Particle Design Ltd Method for the formation of particles
US6521258B1 (en) * 2000-09-08 2003-02-18 Ferro Corporation Polymer matrices prepared by supercritical fluid processing techniques
EP1334765B1 (en) * 2000-10-13 2010-06-30 National Institute of Advanced Industrial Science and Technology Process for producing liposome
GB0027357D0 (en) 2000-11-09 2000-12-27 Bradford Particle Design Plc Particle formation methods and their products
US20020130430A1 (en) * 2000-12-29 2002-09-19 Castor Trevor Percival Methods for making polymer microspheres/nanospheres and encapsulating therapeutic proteins and other products
US7708915B2 (en) 2004-05-06 2010-05-04 Castor Trevor P Polymer microspheres/nanospheres and encapsulating therapeutic proteins therein
CA2445947A1 (en) * 2001-04-30 2002-11-07 Targeted Genetics Corporation Lipid-comprising drug delivery complexes and methods for their production
GB0117696D0 (en) * 2001-07-20 2001-09-12 Bradford Particle Design Plc Particle information
US20050069596A1 (en) * 2001-10-03 2005-03-31 Gow Robert T. Compositions and methods comprising kava and anti-anxiety compounds
US7001620B2 (en) 2001-10-03 2006-02-21 Herbal Science, Llc Kavalactone product
US7037524B2 (en) * 2001-10-03 2006-05-02 Herbalscience, Llc Oral delivery of a botanical
US7029707B2 (en) * 2001-10-03 2006-04-18 Herbalscience, Llc Method of producing a processed kava product having an altered kavalactone distribution and processed kava products produced using the same
US7105185B2 (en) 2001-10-03 2006-09-12 Herbalscience, Llc Kavalactone profile
US7291352B2 (en) 2001-10-03 2007-11-06 Herbalscience Llc Methods and compositions for oral delivery of Areca and mate' or theobromine
DE10205130A1 (de) * 2002-02-07 2003-08-28 Air Liquide Gmbh Verfahren zum unterbrechungsfreien Bereitstellen von flüssigem, unterkühltem Kohlendioxid bei konstantem Druck oberhalb von 40 bar sowie Versorgungssystem
GB0216562D0 (en) 2002-04-25 2002-08-28 Bradford Particle Design Ltd Particulate materials
US9339459B2 (en) 2003-04-24 2016-05-17 Nektar Therapeutics Particulate materials
US6966990B2 (en) 2002-10-11 2005-11-22 Ferro Corporation Composite particles and method for preparing
WO2004069224A2 (en) * 2003-02-03 2004-08-19 Neopharm, Inc. Stable sterile filterable liposomal encapsulated taxane and other antineoplastic drugs
US7083748B2 (en) * 2003-02-07 2006-08-01 Ferro Corporation Method and apparatus for continuous particle production using supercritical fluid
US6931888B2 (en) 2003-02-07 2005-08-23 Ferro Corporation Lyophilization method and apparatus for producing particles
US20060008531A1 (en) * 2003-05-08 2006-01-12 Ferro Corporation Method for producing solid-lipid composite drug particles
CA2524773C (en) * 2003-05-08 2014-04-08 Nektar Therapeutics Uk Ltd Particulate coformulations of active substances with excipients
JP2005170923A (ja) * 2003-10-21 2005-06-30 Konica Minolta Medical & Graphic Inc リポソーム含有ｘ線造影剤およびその製造方法
US7294353B2 (en) * 2003-10-24 2007-11-13 Herbalscience, Llc Methods and compositions comprising ilex
CN1917892A (zh) * 2003-10-24 2007-02-21 草本制药科学有限责任公司 包含冬青的方法和组合物
JP4595319B2 (ja) * 2003-12-03 2010-12-08 コニカミノルタエムジー株式会社 リポソーム用脂質、リポソームおよびそれらの製造方法
JP2005162702A (ja) * 2003-12-04 2005-06-23 Konica Minolta Medical & Graphic Inc リポソーム製剤の製造方法、リポソーム製剤およびその製造装置
JP4649841B2 (ja) * 2004-02-18 2011-03-16 コニカミノルタエムジー株式会社 リポソーム含有製剤の製造方法、およびリポソーム含有製剤
JPWO2006009022A1 (ja) * 2004-07-21 2008-05-01 コニカミノルタエムジー株式会社 リポソーム含有ｘ線造影剤およびその製造方法
EP1776948B1 (en) * 2004-08-11 2015-12-09 Konica Minolta Medical & Graphic, Inc. Method of producing liposome-containing preparation
JP2006056807A (ja) * 2004-08-18 2006-03-02 Konica Minolta Medical & Graphic Inc 光線力学療法製剤
JP4715133B2 (ja) * 2004-08-26 2011-07-06 コニカミノルタエムジー株式会社 抗腫瘍リポソーム製剤およびその製造方法
JP2006069929A (ja) * 2004-08-31 2006-03-16 Konica Minolta Medical & Graphic Inc 真菌症治療製剤およびその製造方法
ES2265262B1 (es) * 2005-01-31 2008-03-01 Activery Biotech, S.L.(Titular Al 50%) Procedimiento para la obtencion de sistemas micro- y nanodispersos.
US20060239925A1 (en) * 2005-04-21 2006-10-26 Konica Minolta Medical & Graphic, Inc. Method of manufacturing pharmaceutical preparation containing liposomes
MX2007015577A (es) * 2005-06-09 2008-02-25 Biolipox Ab Metodo y composiciones para el tratamiento de trastornos inflamatorios.
ES2292300B1 (es) * 2005-07-19 2009-02-16 Sociedad Española De Carburos Metalicos, S.A.(Titular Al 50%) Procedimiento para la obtencion de un material compuesto.
EP1920765A1 (en) * 2006-11-07 2008-05-14 Medigene AG Liposome preparation by single-pass process
KR100811447B1 (ko) * 2006-12-05 2008-03-11 재단법인서울대학교산학협력재단 초임계 유체를 이용한 세라마이드 나노입자 제조방법
EP3494964B1 (en) * 2007-05-14 2021-04-07 Konica Minolta Holdings, Inc. Liposome and method for producing liposome
CN101918123B (zh) * 2007-12-07 2013-12-18 X喷雾微粒公司 生产微粒的方法与装置
US8637074B2 (en) * 2009-03-31 2014-01-28 Aphios Corporation Methods for co-encapsulation of combination drugs and co-encapsulated combination drug product
KR101102834B1 (ko) * 2010-02-24 2012-01-05 충남대학교산학협력단 신규한 리포좀 제조 방법 및 장치
WO2011127456A2 (en) 2010-04-09 2011-10-13 Pacira Pharmaceuticals, Inc. Method for formulating large diameter synthetic membrane vesicles
KR101795019B1 (ko) * 2010-06-16 2017-12-01 초임계연구소 주식회사 봉입물질의 열변성을 방지하는 저온 리포좀 제조방법
KR101047873B1 (ko) * 2010-06-23 2011-07-08 주식회사 에프씨비투웰브 인체유래 줄기세포 배양액 추출물을 포접시킨 리포좀을 함유하는 화장료 조성물
US9981238B2 (en) * 2010-08-25 2018-05-29 Aphios Corporation Apparatus and methods for making nanosomes loaded with nucleic acid
US9808030B2 (en) 2011-02-11 2017-11-07 Grain Processing Corporation Salt composition
US20140112979A1 (en) 2011-07-04 2014-04-24 Statens Serum Institut Methods for producing liposomes
CN105050409B (zh) * 2012-07-30 2018-05-25 马丁尼斯生物制药纳米技术公司 使用大豆磷脂酰丝氨酸制备的脂质卷
JP6373749B2 (ja) 2014-12-19 2018-08-15 富士フイルム株式会社 リポソームの製造方法及びリポソーム製造装置
CN109291298B (zh) * 2018-09-30 2024-03-29 苏州艾特森制药设备有限公司 一种微量脂质体高压挤出装置
US11278494B1 (en) 2021-01-22 2022-03-22 Pacira Pharmaceuticals, Inc. Manufacturing of bupivacaine multivesicular liposomes
US11033495B1 (en) 2021-01-22 2021-06-15 Pacira Pharmaceuticals, Inc. Manufacturing of bupivacaine multivesicular liposomes
US11357727B1 (en) 2021-01-22 2022-06-14 Pacira Pharmaceuticals, Inc. Manufacturing of bupivacaine multivesicular liposomes
DE102021130372A1 (de) 2021-11-19 2023-05-25 Deutsches Zentrum für Luft- und Raumfahrt e.V. Verfahren und Anordnung zur Herstellung eines Treibstoffgemisches

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2521565B1 (fr) * 1982-02-17 1985-07-05 Dior Sa Parfums Christian Melange pulverulent de constituants lipidiques et de constituants hydrophobes, procede pour le preparer, phases lamellaires lipidiques hydratees et procede de fabrication, compositions pharmaceutiques ou cosmetiques comportant des phases lamellaires lipidiques hydratees
FR2543018B1 (fr) * 1983-03-22 1985-07-26 Oreal Procede de preparation de vesicules lipidiques par vaporisation de solvants
GB8613811D0 (en) * 1986-06-06 1986-07-09 Phares Pharm Res Nv Composition & method
US5141674A (en) * 1984-03-08 1992-08-25 Phares Pharmaceutical Research N.V. Methods of preparing pro-liposome dispersions and aerosols
GB8423436D0 (en) * 1984-09-17 1984-10-24 Riker Laboratories Inc Preparation of liposomes
GB8502892D0 (en) * 1985-02-05 1985-03-06 Sterwin Ag Aerosol composition
US5192528A (en) * 1985-05-22 1993-03-09 Liposome Technology, Inc. Corticosteroid inhalation treatment method
US4752425A (en) * 1986-09-18 1988-06-21 Liposome Technology, Inc. High-encapsulation liposome processing method
EP0285638A4 (en) * 1986-09-18 1989-06-14 Liposome Technology Inc METHOD FOR PRODUCING A HIGH DENSITY LIPOSOME.
DE3812816A1 (de) * 1988-04-16 1989-11-02 Lawaczeck Ruediger Dipl Phys P Verfahren zur solubilisierung von liposomen und/oder biologischer membranen sowie deren verwendung
US5305757A (en) * 1989-12-22 1994-04-26 Unger Evan C Gas filled liposomes and their use as ultrasonic contrast agents
US5088499A (en) * 1989-12-22 1992-02-18 Unger Evan C Liposomes as contrast agents for ultrasonic imaging and methods for preparing the same

Also Published As

Publication number Publication date
US5554382A (en) 1996-09-10
NO954756L (no) 1996-01-26
FI955727A0 (sv) 1995-11-28
DE69403077D1 (de) 1997-06-12
CA2163903A1 (en) 1994-12-08
NO954756D0 (no) 1995-11-24
ATE152615T1 (de) 1997-05-15
DE69403077T2 (de) 1997-11-13
AU6919094A (en) 1994-12-20
FI115115B (sv) 2005-03-15
EP0703778B1 (en) 1997-05-07
KR960702748A (ko) 1996-05-23
WO1994027581A1 (en) 1994-12-08
EP0703778A1 (en) 1996-04-03
JP3742427B2 (ja) 2006-02-01
JPH09502644A (ja) 1997-03-18

Similar Documents

Publication Publication Date Title
FI955727A (sv) Förfarande och anordning för framställning av liposomer
AU4246296A (en) Methods and apparatus for making liposomes containing hydrophobic drugs
AU1549295A (en) Method in dialysis and dialyzer for working the method
AU647503B2 (en) Low fluid pressure dual-sided fiber entaglement method, apparatus and resulting product
FI971530A0 (sv) Lipas, mikroorganism som producerar detta, förfarande för framställning av lipaset och användning av detta
AU2002235257A1 (en) Multistage hemodiafiltration/hemofiltration method and apparatus
AU638024B2 (en) Apparatus and method for pumping, homogenizing and dividing dough and the like
AU2001298000A1 (en) Apparatus and method for regulating fluid pump pressures
SE9703916D0 (sv) Förfarande för framställning av dekorativt laminat, dekorativt laminat och användning därav
AR021982A1 (es) Un producto alimenticio que comprende burbujas de gas
AU1704795A (en) A method for injecting a product into a fluid, and an apparatus for carrying out the method
DE69204605D1 (de) Luftblasenerkennungsverfahren für Infusionspumpen.
DE69233119D1 (de) Neue liposomale arzneimittelfreisetzungssysteme
AU5211793A (en) Safety valve for high-pressure pumps, high-pressure water jet machines or the like
AU4448897A (en) Method for controlling the speed of a pump based on measurement of the fluid depth in a well
MX9202421A (es) Metodo y aparato para la produccion de fluidos.
FI955912A0 (sv) Elektroluminescensfärganordning och förfarande för framställning av densamma
AU2465695A (en) Structure forming method, apparatus and the resulting product
IT1274885B (it) Metodo per la regolazione della pressione di una macchina idrostatica a portata variabile.
DE69310552D1 (de) Hochdruckpumsystem und dessen betriebsverfahren
AU6626990A (en) Downhole pump unseating apparatus and method
TR28357A (tr) Karboksi-arensulfonik asitlerin ve bunlarin karbonik asit türevlerinin üretilmesine mahsus usul.
AU2191895A (en) Method and apparatus for fracturing connecting rods and the like
IT1266845B1 (it) Metodo per la fabbricazione di un rotore in un magnete.
FI99101B (sv) Förfarande och anordning för åstadkommande av tecken eller figurer

Legal Events

Date Code Title Description
FG Patent granted

Ref document number: 115115

Country of ref document: FI

MA Patent expired