FI95570C - Menetelmä lääkinnällisesti vaikuttavien pyridatsinoni-3(2H)-onijohdannaisten valmistamiseksi - Google Patents

Menetelmä lääkinnällisesti vaikuttavien pyridatsinoni-3(2H)-onijohdannaisten valmistamiseksi

Info

Publication number
FI95570C
FI95570C FI894844A FI894844A FI95570C FI 95570 C FI95570 C FI 95570C FI 894844 A FI894844 A FI 894844A FI 894844 A FI894844 A FI 894844A FI 95570 C FI95570 C FI 95570C
Authority
FI
Finland
Prior art keywords
derivatives
preparation
pharmaceutically active
pyridazinone
active pyridazinone
Prior art date
Application number
FI894844A
Other languages
English (en)
Swedish (sv)
Other versions
FI894844A0 (fi
FI95570B (fi
Inventor
You Kusase
Masatoshi Murakata
Nobuo Mochizuki
Michinori Takebayashi
Original Assignee
Nippon Soda Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nippon Soda Co filed Critical Nippon Soda Co
Publication of FI894844A0 publication Critical patent/FI894844A0/fi
Application granted granted Critical
Publication of FI95570B publication Critical patent/FI95570B/fi
Publication of FI95570C publication Critical patent/FI95570C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/04—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having less than three double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D237/14—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/26—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings condensed with carbocyclic rings or ring systems
    • C07D237/36—Benzo-cinnolines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Hospice & Palliative Care (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Obesity (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
FI894844A 1988-02-13 1989-10-12 Menetelmä lääkinnällisesti vaikuttavien pyridatsinoni-3(2H)-onijohdannaisten valmistamiseksi FI95570C (fi)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP3161888 1988-02-13
JP7591088 1988-03-31
PCT/JP1989/000127 WO1989007594A1 (en) 1988-02-13 1989-02-09 Pyridazinone derivatives

Publications (3)

Publication Number Publication Date
FI894844A0 FI894844A0 (fi) 1989-10-12
FI95570B FI95570B (fi) 1995-11-15
FI95570C true FI95570C (fi) 1996-02-26

Family

ID=26370117

Family Applications (1)

Application Number Title Priority Date Filing Date
FI894844A FI95570C (fi) 1988-02-13 1989-10-12 Menetelmä lääkinnällisesti vaikuttavien pyridatsinoni-3(2H)-onijohdannaisten valmistamiseksi

Country Status (11)

Country Link
US (1) US5110925A (fi)
EP (1) EP0357788B1 (fi)
JP (1) JP2717687B2 (fi)
KR (1) KR910005233B1 (fi)
CA (1) CA1320957C (fi)
DE (1) DE68910447T2 (fi)
DK (1) DK170096B1 (fi)
ES (1) ES2012646A6 (fi)
FI (1) FI95570C (fi)
NO (1) NO176275C (fi)
WO (1) WO1989007594A1 (fi)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8903130D0 (en) * 1989-02-11 1989-03-30 Orion Yhtymae Oy Substituted pyridazinones
JP2806192B2 (ja) * 1992-11-02 1998-09-30 日本曹達株式会社 血小板凝集抑制剤
US5678114A (en) * 1994-06-14 1997-10-14 Noritsu Koki Co., Ltd. Automatic photographic developing apparatus for photosensitive materials
CA2204915A1 (en) * 1994-11-11 1996-05-23 Seiichi Uchida Optically active compound
EP0961616A4 (en) * 1996-09-13 2000-11-22 Trustees Of Board Of NON-HORMONAL CONTRACEPTIVE METHOD
AU6005999A (en) * 1998-10-09 2000-05-01 Nihon Nohyaku Co., Ltd. Pyridazinone derivatives
US7772188B2 (en) 2003-01-28 2010-08-10 Ironwood Pharmaceuticals, Inc. Methods and compositions for the treatment of gastrointestinal disorders
CN101355876B (zh) 2005-11-09 2012-09-05 康宾纳特克斯公司 一种适用于眼部给药的组合物
US8969514B2 (en) 2007-06-04 2015-03-03 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
AU2008261102B2 (en) 2007-06-04 2013-11-28 Bausch Health Ireland Limited Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
CA2930674A1 (en) 2008-06-04 2009-12-10 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
JP2011528375A (ja) 2008-07-16 2011-11-17 シナジー ファーマシューティカルズ インコーポレイテッド 胃腸障害、炎症、癌、およびその他の障害の治療のために有用なグアニル酸シクラーゼのアゴニスト
US9616097B2 (en) 2010-09-15 2017-04-11 Synergy Pharmaceuticals, Inc. Formulations of guanylate cyclase C agonists and methods of use
CN108676076A (zh) 2011-03-01 2018-10-19 辛纳吉制药公司 制备鸟苷酸环化酶c激动剂的方法
US20150119399A1 (en) 2012-01-10 2015-04-30 President And Fellows Of Harvard College Beta-cell replication promoting compounds and methods of their use
EP3718557A3 (en) 2013-02-25 2020-10-21 Bausch Health Ireland Limited Guanylate cyclase receptor agonist sp-333 for use in colonic cleansing
CA2905438A1 (en) 2013-03-15 2014-09-25 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase and their uses
JP2016514670A (ja) 2013-03-15 2016-05-23 シナジー ファーマシューティカルズ インコーポレイテッド 他の薬物と組み合わせたグアニル酸シクラーゼ受容体アゴニスト
JP6606491B2 (ja) 2013-06-05 2019-11-13 シナジー ファーマシューティカルズ インコーポレイテッド グアニル酸シクラーゼｃの超高純度アゴニスト、その作成および使用方法
NZ717739A (en) 2013-08-09 2023-12-22 Ardelyx Inc Compounds and methods for inhibiting phosphate transport
WO2015031824A1 (en) * 2013-08-30 2015-03-05 Icahn School Of Medicine At Mount Sinai Cyclic vinylogous amides as bromodomain inhibitors
US20200368223A1 (en) 2019-05-21 2020-11-26 Ardelyx, Inc. Methods for inhibiting phosphate transport

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4019575A (en) * 1975-12-22 1977-04-26 Chevron Research Company System for recovering viscous petroleum from thick tar sand
JPS5746966A (en) * 1980-09-03 1982-03-17 Mitsui Toatsu Chem Inc Pyridazinone derivative and its production
US4665174A (en) * 1981-05-12 1987-05-12 Sumitomo Chemical Company, Limited Production of cyclopentenone derivatives
JPS58113180A (ja) * 1981-12-28 1983-07-05 Mitsui Toatsu Chem Inc ピリダジノン誘導体
DE3302442A1 (de) * 1983-01-26 1984-07-26 Basf Ag, 6700 Ludwigshafen Neue pyridazinone, verfahren zu ihrer herstellung, diese verbindungen enthaltende therapeutische mittel und deren verwendung
US4602019A (en) * 1983-04-22 1986-07-22 Warner-Lambert Company Indeno[1,2-c]pyridazin-3-one derivatives useful as cardiotonic and antihypertensive agents
US4666902A (en) * 1983-06-20 1987-05-19 Cassella Aktiengesellschaft Tetrahydropyridazinone derivatives, processes for their preparation and their use
GB2164643B (en) * 1984-07-27 1988-11-02 Boehringer Biochemia Srl Tricyclic dihydropyridazinones and pharmaceutical compositions containing them
JPH06763B2 (ja) * 1984-08-28 1994-01-05 吉富製薬株式会社 ベンゾ〔ｈ〕シンノリン誘導体
US4816454A (en) * 1984-09-21 1989-03-28 Cassella Aktiengesellschaft 4,5-dihydro-3(2H)-pyridazinones and their pharmacological use
US4681621A (en) * 1984-12-20 1987-07-21 Stauffer Chemical Company Herbicidal 2-(2-substituted benzoyl)-1,3-cyclopentanediones
DE3505609A1 (de) * 1985-02-19 1986-08-21 Merck Patent Gmbh, 6100 Darmstadt Benzimidazolyl-pyridazinone
GB2177689B (en) * 1985-07-09 1989-07-19 Boehringer Biochemia Srl Tricyclic dihydropyridazinones and pharmaceutical compositions containing them
JPH0633277B2 (ja) * 1986-01-10 1994-05-02 吉富製薬株式会社 ベンゾチオピラノ〔４，３−ｃ〕ピリダジン化合物
US4775411A (en) * 1986-06-09 1988-10-04 Stauffer Chemica Company Certain substituted 3-amino-2-benzoylcyclohex-2-enones
EP0281045B1 (en) * 1987-03-02 1991-12-27 Yoshitomi Pharmaceutical Industries, Ltd. Benzothiepino (5,4-c) pyridazine compounds and their pharmaceutical uses
DE3804490A1 (de) * 1988-02-12 1989-08-24 Heumann Pharma Gmbh & Co Substituierte 6-phenyldihydro-3(2h)-pyridazinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
JPH0216991A (ja) * 1988-07-04 1990-01-19 Mitsui Toatsu Chem Inc Ｌ−トリプトファンの製法

Also Published As

Publication number Publication date
US5110925A (en) 1992-05-05
JP2717687B2 (ja) 1998-02-18
FI894844A0 (fi) 1989-10-12
EP0357788B1 (en) 1993-11-03
KR900700462A (ko) 1990-08-13
KR910005233B1 (ko) 1991-07-24
JPH0256468A (ja) 1990-02-26
NO176275C (no) 1995-03-08
CA1320957C (en) 1993-08-03
DE68910447T2 (de) 1994-03-17
NO894088D0 (no) 1989-10-12
NO894088L (no) 1989-10-12
DK170096B1 (da) 1995-05-22
EP0357788A1 (en) 1990-03-14
DK502389D0 (da) 1989-10-10
ES2012646A6 (es) 1990-04-01
WO1989007594A1 (en) 1989-08-24
DE68910447D1 (de) 1993-12-09
NO176275B (no) 1994-11-28
FI95570B (fi) 1995-11-15
DK502389A (da) 1989-11-20

Similar Documents

Publication Publication Date Title
FI95570C (fi) Menetelmä lääkinnällisesti vaikuttavien pyridatsinoni-3(2H)-onijohdannaisten valmistamiseksi
FI96861C (fi) Menetelmä terapeuttisesti aktiivisten substituoitujen indolyylipyrrolijohdannaisten valmistamiseksi
FI91152B (fi) Menetelmä terapeuttisesti aktiivisten bentsimidatsolijohdannaisten valmistamiseksi
NO914667L (no) Fremgangsmaate for fremstilling av terapeutisk aktive arylderivater
NO173545C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive kinazolinderivater
NO904694D0 (no) Fremgangsmaate for fremstilling av terapeutisk aktive imidazolderivater.
NO894630D0 (no) Fremgangsmaate for fremstilling av terapeutisk aktive kinuklidin-derivater.
NO901684L (no) Fremgangsmaate for fremstilling av terapeutisk aktive 3-substituerte-2-oksindol-derivater.
NO174467C (no) Analogifremgangsmåte for fremstilling av terapeutisk aktive kromanderivater
FI890072A0 (fi) Menetelmä farmaseuttisesti käyttökelpoisten isokinoliinijohdannaisten valmistamiseksi
NO173334C (no) Analogifremgangsm}te for fremstilling av terapeutisk aktive alkylaminoalkylenderivater 2H-1-benzopyraner
FI93444B (fi) Menetelmä terapeuttisesti aktiivisten dihydropyridiinijohdannaisten valmistamiseksi
NO173784C (no) Anaslogifremgangsmaate for fremstilling av terapeutisk aktive tieno-tri-azolo-diazepinderivater
NO174391C (no) Analogifremgangsmåte for fremstilling av terapeutisk aktive kromanderivater
NO174422C (no) Analogifremgangsmåte for fremstilling av terapeutisk aktive kromanderivater
NO891723D0 (no) Fremgangsmaate for fremstilling av terapeutisk aktive kinazolin-derivater.
NO173606C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive tieno- triazolo-diazepin-derivater
NO177673C (no) Analogifremgangsmåte for fremstilling av terapeutisk aktive N7-substituerte mitomycinderivater
NO175476C (no) Analogifremgangsmåte ved fremstilling av terapeutisk aktive cykloalkyltiazolderinvater
NO900972D0 (no) Fremgangsmaate for fremstilling av terapeutisk aktive naftalen-derivater.
NO900942D0 (no) Fremgangsmaate for fremstilling av terapeutisk aktive azacyklooktadien-derivater.
FI89595B (fi) Foerfarande foer framstaellning av terapeutiskt aktiva 2-(tioalkylamino)etyl-1H-imidazolderivat
NO890724L (no) Fremgangsmaate for fremstilling av terapeutisk aktive tetraazaacenaftylen-derivater.
NO177568C (no) Analogifremgangsmåte for fremstilling av terapeutisk aktive selenofenderivater
NO890519D0 (no) Fremgangsmaate for fremstilling av terapeutisk aktive propanon-derivater.

Legal Events

Date Code Title Description
BB Publication of examined application
MM Patent lapsed

Owner name: NIPPON SODA CO., LTD.