FI954386A0 - (1,2,4)triatsolo(4,3-a)kinoksaalinijohdannaiset, niiden valmistus ja käyttö - Google Patents

(1,2,4)triatsolo(4,3-a)kinoksaalinijohdannaiset, niiden valmistus ja käyttö

Info

Publication number
FI954386A0
FI954386A0 FI954386A FI954386A FI954386A0 FI 954386 A0 FI954386 A0 FI 954386A0 FI 954386 A FI954386 A FI 954386A FI 954386 A FI954386 A FI 954386A FI 954386 A0 FI954386 A0 FI 954386A0
Authority
FI
Finland
Prior art keywords
triazolo
preparation
quinoxaline derivative
quinoxaline
derivative
Prior art date
Application number
FI954386A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI954386A (fi
Inventor
Poul Jacobsen
Flemming Elmelund Nielsen
Lone Jeppesen
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Publication of FI954386A publication Critical patent/FI954386A/fi
Publication of FI954386A0 publication Critical patent/FI954386A0/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
FI954386A 1993-03-19 1995-09-18 (1,2,4)triatsolo(4,3-a)kinoksaalinijohdannaiset, niiden valmistus ja käyttö FI954386A0 (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK93310A DK31093D0 (fr) 1993-03-19 1993-03-19
PCT/DK1994/000077 WO1994021639A1 (fr) 1993-03-19 1994-02-25 DERIVES DE [1,2,4] TRIAZOLO [4,3-a] QUINOXALINE, LEUR PREPARATION ET LEUR UTILISATION

Publications (2)

Publication Number Publication Date
FI954386A FI954386A (fi) 1995-09-18
FI954386A0 true FI954386A0 (fi) 1995-09-18

Family

ID=8092112

Family Applications (1)

Application Number Title Priority Date Filing Date
FI954386A FI954386A0 (fi) 1993-03-19 1995-09-18 (1,2,4)triatsolo(4,3-a)kinoksaalinijohdannaiset, niiden valmistus ja käyttö

Country Status (16)

Country Link
US (1) US5559106A (fr)
EP (1) EP0691969A1 (fr)
JP (1) JPH08507536A (fr)
KR (1) KR100313051B1 (fr)
CN (1) CN1041930C (fr)
AU (1) AU685783B2 (fr)
CA (1) CA2158545A1 (fr)
DK (1) DK31093D0 (fr)
FI (1) FI954386A0 (fr)
HU (1) HUT73419A (fr)
IL (1) IL108800A (fr)
NO (1) NO305286B1 (fr)
NZ (1) NZ262365A (fr)
TW (1) TW304195B (fr)
WO (1) WO1994021639A1 (fr)
ZA (1) ZA941926B (fr)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4314592A1 (de) * 1993-04-28 1994-11-03 Schering Ag Benzo(f)chinoxalindionderivate, deren Herstellung und Verwendung in Arzneimitteln
CN1193973A (zh) * 1994-09-16 1998-09-23 诺沃挪第克公司 [1,2,4]三唑并[4,3-α]喹喔啉酮衍生物,其制备和用途
ES2146769T3 (es) * 1994-09-16 2000-08-16 Novo Nordisk As Derivados de (1,2,4)triazolo(4,3-a)quinoxalinonas, su preparacion y utilizacion como antagonistas de receptores de ampa.
US5679680A (en) * 1995-02-16 1997-10-21 Warner-Lambert Company α-substituted hydrazides having calpain inhibitory activity
FR2743363A1 (fr) * 1996-01-10 1997-07-11 Rhone Poulenc Rorer Sa 5h,10h-imidazo(1,2-a)indeno(1,2-e)pyrazine-a-ones substituees en position 2, leur preparation et les medicaments les contenant
IL125950A0 (en) * 1997-09-05 1999-04-11 Pfizer Prod Inc Methods of administering ampa receptor antagonists to treat dyskinesias associated with dopamine agonist therapy
EP1050535A4 (fr) 1997-11-11 2001-04-25 Ono Pharmaceutical Co Composes de pyrazine condenses
WO1999040063A1 (fr) * 1998-02-06 1999-08-12 Yoshitomi Pharmaceutical Industries, Ltd. Nouveaux derives de l'acide hydroxamique de type azapeptide
US20040152694A1 (en) * 2003-02-04 2004-08-05 Istvan Kurucz Methods and compositions for treating inflammatory disorders of the airways
ES2566774T3 (es) * 2006-12-13 2016-04-15 Aska Pharmaceutical Co., Ltd. Derivado de quinoxalina
AU2010219598A1 (en) * 2009-03-05 2011-09-22 Astellas Pharma Inc. Quinoxaline compounds
EP2338492A1 (fr) 2009-12-24 2011-06-29 Universidad del Pais Vasco Procédés et compositions pour le traitement de la maladie d'Alzheimer
WO2012033101A1 (fr) 2010-09-07 2012-03-15 アステラス製薬株式会社 Composé quinoxaline
US10604523B2 (en) 2011-06-27 2020-03-31 Janssen Pharmaceutica Nv 1-aryl-4-methyl-[1,2,4]triazolo[4,3-a]quinoxaline derivatives
RU2657540C2 (ru) 2012-06-26 2018-06-14 Янссен Фармацевтика Нв Комбинации, содержащие ингибиторы pde 2, такие как 1-арил-4-метил-[1,2,4]триазоло[4,3-а]хиноксалиновые соединения, и ингибиторы pde 10, для применения в лечении неврологических или метаболических расстройств

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4354027A (en) * 1980-05-19 1982-10-12 Usv Pharmaceutical Corporation Triazoloquinoxalin-4-ones
US4547501A (en) * 1983-09-02 1985-10-15 Pfizer Inc. Method of using [1,2,4]triazolo[4,3-a]quinoxaline-4-amine derivatives as antidepressant and antifatigue agents
US5153196A (en) * 1991-06-05 1992-10-06 Eli Lilly And Company Excitatory amino acid receptor antagonists and methods for the use thereof
AU3767793A (en) * 1992-04-03 1993-11-08 Yamanouchi Pharmaceutical Co., Ltd. Fused quinoxalinone derivative and pharmaceutical composition containing the same

Also Published As

Publication number Publication date
FI954386A (fi) 1995-09-18
HU9502726D0 (en) 1995-11-28
WO1994021639A1 (fr) 1994-09-29
AU6201894A (en) 1994-10-11
CN1122601A (zh) 1996-05-15
US5559106A (en) 1996-09-24
JPH08507536A (ja) 1996-08-13
HUT73419A (en) 1996-07-29
KR960701057A (ko) 1996-02-24
ZA941926B (en) 1995-09-18
TW304195B (fr) 1997-05-01
DK31093D0 (fr) 1993-03-19
IL108800A0 (en) 1994-06-24
NO953673L (no) 1995-11-17
AU685783B2 (en) 1998-01-29
KR100313051B1 (ko) 2002-02-28
CA2158545A1 (fr) 1994-09-29
IL108800A (en) 1998-02-22
NO305286B1 (no) 1999-05-03
NZ262365A (en) 1997-05-26
NO953673D0 (no) 1995-09-18
CN1041930C (zh) 1999-02-03
EP0691969A1 (fr) 1996-01-17

Similar Documents

Publication Publication Date Title
FI961219A0 (fi) Kemialliset yhdisteet, niiden valmistus ja käyttö
IL92213A0 (en) Foldable chair
IL111526A0 (en) 7H-imidazo (1,2-a) pyrazin-8-one derivatives and their preparation and use
GB2235623B (en) Foldable playyard
IL118812A0 (en) Poly (arylene ether) compounds their preparation and use
DE69529777D1 (de) 2-Benzylthio-8-amino(1,2,4)triazolo(1,5-a)pyridine
NZ232168A (en) Perhydropyrido(1,2-a)pyrazine derivatives; intermediates and pharmaceutical compositions
ITMI922995A0 (it) Granulati di coloranti scorrevoli chimicamente resistenti loro preparazione e loro impiego
FR2744442B1 (fr) Preparation du 1,1,1,3,3-pentachlorobutane et du 1,1,1,3,3,-pentafluorobutane
FI954386A (fi) (1,2,4)triatsolo(4,3-a)kinoksaalinijohdannaiset, niiden valmistus ja käyttö
NO974150D0 (no) 6-arylpyrazolo(3,4-d)pyrimidin-4-oner og preparater og fremgangsmåter for anvendelse derav
FI101382B1 (fi) Dihydroksipropyylisulfoetyyliselluloosia, niiden valmistus ja käyttö
FI923290A (fi) Imidazo(2,1-b)bensotiazol-3-acetamidderivat
EP0511152A3 (en) Quinoxaline compounds, their preparation and use
FI942468A0 (fi) Kemialliset yhdisteet, niiden valmistus ja käyttö
HUP9902883A3 (en) Bis/acridinecarboxamide/ and bis/phenazinecarboxamide/ derivatives as antitumour agents, preparation and use thereof
ITMI912290A1 (it) Miscele di n-alchilftalimmidi, loro preparazione e loro impiego
GB9001148D0 (en) Foldable chair
BR9106372A (pt) Derivados 1,5-benzotiazepinona,suas preparacoes e uso farmaceutico
ITMI931897A0 (it) 1,3,4- benzotriazepin-554h)-one e procedimento per la loro preparazione
OA09565A (fr) Tetrahydro-imidazo [1,4] benzodiazepines antivirales
FI935915A (fi) 2-tienyyli-imidatso(2,1-b)bentsotiatsol-3-etikkahappojohdannaiset, niiden valmistus ja terapeuttinen käyttö
FI973631A (fi) 1,3-diolipohjaiset eetterit, menetelmä 1,3-diolipohjaisten eetterien valmistamiseksi sekä eetterien käyttö
NO170620C (no) Trinse
DK88093D0 (da) Stabilt praeparat