FI951387L - Sulfonamidokarbonyylipyridiini-2-karboksyylihappoesteriamidit sekä niiden pyridiini-N-oksidit, menetelmä niiden valmistamiseksi ja niiden käyttö lääkkeinä - Google Patents

Sulfonamidokarbonyylipyridiini-2-karboksyylihappoesteriamidit sekä niiden pyridiini-N-oksidit, menetelmä niiden valmistamiseksi ja niiden käyttö lääkkeinä Download PDF

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Publication number
FI951387L
FI951387L FI951387A FI951387A FI951387L FI 951387 L FI951387 L FI 951387L FI 951387 A FI951387 A FI 951387A FI 951387 A FI951387 A FI 951387A FI 951387 L FI951387 L FI 951387L
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FI
Finland
Prior art keywords
sulfonamidocarbonylpyridine
pharmaceuticals
pyridine
oxides
preparation
Prior art date
Application number
FI951387A
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English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI951387A0 (fi
FI951387A7 (fi
Inventor
Klaus Weidmann
Martin Bickel
Volkmar Guenzler-Pukall
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of FI951387A0 publication Critical patent/FI951387A0/fi
Publication of FI951387A7 publication Critical patent/FI951387A7/fi
Publication of FI951387L publication Critical patent/FI951387L/fi

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81Amides; Imides
    • C07D213/82Amides; Imides in position 3
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/89Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
FI951387A 1994-03-25 1995-03-23 Sulfonamidokarbonyylipyridiini-2-karboksyylihappoesteriamidit sekä niiden pyridiini-N-oksidit, menetelmä niiden valmistamiseksi ja niiden käyttö lääkkeinä FI951387L (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4410480A DE4410480A1 (de) 1994-03-25 1994-03-25 Sulfonamidocarbonylpyridin-2-carbonsäureesteramide sowie ihre Pyridin-N-oxide, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel

Publications (3)

Publication Number Publication Date
FI951387A0 FI951387A0 (fi) 1995-03-23
FI951387A7 FI951387A7 (fi) 1995-09-26
FI951387L true FI951387L (fi) 1995-09-26

Family

ID=6513896

Family Applications (1)

Application Number Title Priority Date Filing Date
FI951387A FI951387L (fi) 1994-03-25 1995-03-23 Sulfonamidokarbonyylipyridiini-2-karboksyylihappoesteriamidit sekä niiden pyridiini-N-oksidit, menetelmä niiden valmistamiseksi ja niiden käyttö lääkkeinä

Country Status (19)

Country Link
US (1) US5620996A (cs)
EP (1) EP0673932B1 (cs)
JP (1) JPH07278110A (cs)
KR (1) KR950032126A (cs)
AT (1) ATE193702T1 (cs)
AU (1) AU688450B2 (cs)
CA (1) CA2145475A1 (cs)
CZ (1) CZ289536B6 (cs)
DE (2) DE4410480A1 (cs)
DK (1) DK0673932T3 (cs)
ES (1) ES2146676T3 (cs)
FI (1) FI951387L (cs)
GR (1) GR3033706T3 (cs)
HU (1) HUT72598A (cs)
NO (1) NO304265B1 (cs)
NZ (1) NZ270784A (cs)
PL (1) PL180678B1 (cs)
PT (1) PT673932E (cs)
ZA (1) ZA952409B (cs)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT798296E (pt) * 1996-03-21 2004-04-30 Lonza Ag Processo para a producao de arilamidas de acidos carboxilicos heteroaromaticos
SK283920B6 (sk) 1996-03-28 2004-05-04 Lonza Ag Spôsob výroby arylamidov heteroaromatických karboxylových kyselín
ATE189815T1 (de) * 1996-05-09 2000-03-15 Lonza Ag Verfahren zur herstellung von arylamiden heteroaromatischer carbonsäuren
CA2209392C (en) * 1996-07-23 2007-02-20 Yves Bessard Process for preparing pyridinecarboxylic esters
US6169183B1 (en) 1996-07-23 2001-01-02 Lonza, Ltd. Process for preparing pyridinecarboxylic esters
DE19742951A1 (de) 1997-09-29 1999-04-15 Hoechst Schering Agrevo Gmbh Acylsulfamoylbenzoesäureamide, diese enthaltende nutzpflanzenschützende Mittel und Verfahren zu ihrer Herstellung
EP2295060B1 (en) 2001-12-06 2018-10-31 Fibrogen, Inc. Treatment or prevention of ischemic or hypoxic conditions
WO2003053997A2 (en) 2001-12-06 2003-07-03 Fibrogen, Inc. Methods of increasing endogenous erythropoietin (epo)
US7618940B2 (en) * 2002-12-06 2009-11-17 Fibrogen, Inc. Fat regulation
US8124582B2 (en) * 2002-12-06 2012-02-28 Fibrogen, Inc. Treatment of diabetes
US8614204B2 (en) 2003-06-06 2013-12-24 Fibrogen, Inc. Enhanced erythropoiesis and iron metabolism
EP1491527A1 (en) * 2003-06-25 2004-12-29 Bayer CropScience GmbH Process for preparing acylsulfamoylbenzamides
CN101242817B (zh) 2005-06-15 2016-08-31 菲布罗根公司 HIF1α调节剂在治疗癌症中的用途
ES2619522T3 (es) * 2006-03-30 2017-06-26 Lg Electronics, Inc. Un método y un aparato para descodificar/codificar una señal de video multivisión
EP3026044B8 (en) 2006-06-26 2018-12-19 Akebia Therapeutics, Inc. Prolyl hydroxylase inhibitors and methods of use
US8962530B2 (en) * 2007-06-27 2015-02-24 Regents Of The University Of Colorado Inflammatory bowel disease therapies
NO2686520T3 (cs) 2011-06-06 2018-03-17
WO2014200773A2 (en) 2013-06-13 2014-12-18 Akebia Therapeutics , Inc. Compositions and methods for treating anemia
CN105916502A (zh) 2013-11-15 2016-08-31 阿克比治疗有限公司 {[5-(3-氯苯基)-3-羟基吡啶-2-羰基]氨基}乙酸的固体形式,其组合物和用途
WO2016118858A1 (en) 2015-01-23 2016-07-28 Akebia Therapeutics, Inc. Solid forms of 2-(5-(3-fluorophenyl)-3-hydroxypicolinamido)acetic acid, compositions, and uses thereof
NZ735973A (en) 2015-04-01 2023-06-30 Akebia Therapeutics Inc Compositions and methods for treating anemia
CN105130888A (zh) * 2015-10-09 2015-12-09 中国药科大学 炔基吡啶类脯氨酰羟化酶抑制剂、其制备方法和医药用途
US11713298B2 (en) 2018-05-09 2023-08-01 Akebia Therapeutics, Inc. Process for preparing 2-[[5-(3-chlorophenyl)-3-hydroxypyridine-2-carbonyl]amino]acetic acid
US11524939B2 (en) 2019-11-13 2022-12-13 Akebia Therapeutics, Inc. Solid forms of {[5-(3-chlorophenyl)-3-hydroxypyridine-2-carbonyl]amino} acetic acid

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0541042A1 (de) * 1991-11-05 1993-05-12 Hoechst Aktiengesellschaft Pyridin-2,4- und 2,5-dicarbonsäureamide und deren Derivate, Verfahren zu ihrer Herstellung sowie deren Verwendung als Arzneimittel
TW352384B (en) * 1992-03-24 1999-02-11 Hoechst Ag Sulfonamido- or sulfonamidocarbonylpyridine-2-carboxamides, process for their preparation and their use as pharmaceuticals

Also Published As

Publication number Publication date
DE59508440D1 (de) 2000-07-13
KR950032126A (ko) 1995-12-20
JPH07278110A (ja) 1995-10-24
CA2145475A1 (en) 1995-09-26
NO951149D0 (no) 1995-03-24
HUT72598A (en) 1996-05-28
NZ270784A (en) 1997-02-24
EP0673932A1 (de) 1995-09-27
PL180678B1 (pl) 2001-03-30
AU1504395A (en) 1995-10-05
CZ289536B6 (cs) 2002-02-13
DE4410480A1 (de) 1995-09-28
ZA952409B (en) 1995-11-28
FI951387A0 (fi) 1995-03-23
ES2146676T3 (es) 2000-08-16
FI951387A7 (fi) 1995-09-26
DK0673932T3 (da) 2000-09-18
CZ73495A3 (en) 1995-11-15
PL307847A1 (en) 1995-10-02
US5620996A (en) 1997-04-15
EP0673932B1 (de) 2000-06-07
AU688450B2 (en) 1998-03-12
ATE193702T1 (de) 2000-06-15
NO304265B1 (no) 1998-11-23
PT673932E (pt) 2000-09-29
NO951149L (no) 1995-09-26
HK1011973A1 (en) 1999-07-23
GR3033706T3 (en) 2000-10-31

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