NO304265B1 - Sulfonamidokarbonylpyridin-2-karboksylsyreesteramider samt deres pyridin-N-oksyd og deres anvendelse som legemiddel - Google Patents

Sulfonamidokarbonylpyridin-2-karboksylsyreesteramider samt deres pyridin-N-oksyd og deres anvendelse som legemiddel

Info

Publication number
NO304265B1
NO304265B1 NO951149A NO951149A NO304265B1 NO 304265 B1 NO304265 B1 NO 304265B1 NO 951149 A NO951149 A NO 951149A NO 951149 A NO951149 A NO 951149A NO 304265 B1 NO304265 B1 NO 304265B1
Authority
NO
Norway
Prior art keywords
alkyl
bond
pyridine
opt
sic
Prior art date
Application number
NO951149A
Other languages
English (en)
Norwegian (no)
Other versions
NO951149L (no
NO951149D0 (no
Inventor
Klaus Weidmann
Martin Bickel
Nzler-Pukall Volkmar G
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of NO951149D0 publication Critical patent/NO951149D0/no
Publication of NO951149L publication Critical patent/NO951149L/no
Publication of NO304265B1 publication Critical patent/NO304265B1/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81Amides; Imides
    • C07D213/82Amides; Imides in position 3
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/89Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Pulmonology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
NO951149A 1994-03-25 1995-03-24 Sulfonamidokarbonylpyridin-2-karboksylsyreesteramider samt deres pyridin-N-oksyd og deres anvendelse som legemiddel NO304265B1 (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4410480A DE4410480A1 (de) 1994-03-25 1994-03-25 Sulfonamidocarbonylpyridin-2-carbonsäureesteramide sowie ihre Pyridin-N-oxide, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel

Publications (3)

Publication Number Publication Date
NO951149D0 NO951149D0 (no) 1995-03-24
NO951149L NO951149L (no) 1995-09-26
NO304265B1 true NO304265B1 (no) 1998-11-23

Family

ID=6513896

Family Applications (1)

Application Number Title Priority Date Filing Date
NO951149A NO304265B1 (no) 1994-03-25 1995-03-24 Sulfonamidokarbonylpyridin-2-karboksylsyreesteramider samt deres pyridin-N-oksyd og deres anvendelse som legemiddel

Country Status (19)

Country Link
US (1) US5620996A (cs)
EP (1) EP0673932B1 (cs)
JP (1) JPH07278110A (cs)
KR (1) KR950032126A (cs)
AT (1) ATE193702T1 (cs)
AU (1) AU688450B2 (cs)
CA (1) CA2145475A1 (cs)
CZ (1) CZ289536B6 (cs)
DE (2) DE4410480A1 (cs)
DK (1) DK0673932T3 (cs)
ES (1) ES2146676T3 (cs)
FI (1) FI951387A7 (cs)
GR (1) GR3033706T3 (cs)
HU (1) HUT72598A (cs)
NO (1) NO304265B1 (cs)
NZ (1) NZ270784A (cs)
PL (1) PL180678B1 (cs)
PT (1) PT673932E (cs)
ZA (1) ZA952409B (cs)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0798296T3 (da) * 1996-03-21 2004-04-05 Lonza Ag Fremgangsmåde til fremstilling af arylamider af heteroaromatiske carboxylsyrer
SK283920B6 (sk) 1996-03-28 2004-05-04 Lonza Ag Spôsob výroby arylamidov heteroaromatických karboxylových kyselín
DK0806415T3 (da) * 1996-05-09 2000-06-05 Lonza Ag Fremgangsmåde til fremstilling af arylamider af heteroaromatiske carboxylsyrer
US6169183B1 (en) 1996-07-23 2001-01-02 Lonza, Ltd. Process for preparing pyridinecarboxylic esters
CA2209392C (en) * 1996-07-23 2007-02-20 Yves Bessard Process for preparing pyridinecarboxylic esters
DE19742951A1 (de) * 1997-09-29 1999-04-15 Hoechst Schering Agrevo Gmbh Acylsulfamoylbenzoesäureamide, diese enthaltende nutzpflanzenschützende Mittel und Verfahren zu ihrer Herstellung
EP3520784A1 (en) * 2001-12-06 2019-08-07 Fibrogen, Inc. Hif prolyl hydroxylase inhibitor for treatment of anemia
EP2295060B1 (en) 2001-12-06 2018-10-31 Fibrogen, Inc. Treatment or prevention of ischemic or hypoxic conditions
US7618940B2 (en) * 2002-12-06 2009-11-17 Fibrogen, Inc. Fat regulation
US8124582B2 (en) * 2002-12-06 2012-02-28 Fibrogen, Inc. Treatment of diabetes
US8614204B2 (en) 2003-06-06 2013-12-24 Fibrogen, Inc. Enhanced erythropoiesis and iron metabolism
EP1491527A1 (en) * 2003-06-25 2004-12-29 Bayer CropScience GmbH Process for preparing acylsulfamoylbenzamides
MX2007016160A (es) 2005-06-15 2008-03-07 Fibrogen Inc Uso de moduladoers de hif-1 alfa para el tratamiento contra el cancer.
KR100949981B1 (ko) * 2006-03-30 2010-03-29 엘지전자 주식회사 비디오 신호를 디코딩/인코딩하기 위한 방법 및 장치
PT2044005E (pt) 2006-06-26 2010-12-17 Warner Chilcott Co Llc Inibidores da prolil hidroxilase e métodos de utilização
WO2009002533A1 (en) * 2007-06-27 2008-12-31 The Brigham And Women's Hospital, Inc. Inflammatory bowel disease therapies
NO2686520T3 (cs) 2011-06-06 2018-03-17
SMT202400092T1 (it) 2013-06-13 2024-05-14 Akebia Therapeutics Inc Composizioni e metodi per il trattamento dell'anemia
EP3068394A4 (en) 2013-11-15 2017-04-26 Akebia Therapeutics Inc. Solid forms of {[5-(3-chlorophenyl)-3-hydroxypyridine-2-carbonyl]amino}acetic acid, compositions, and uses thereof
EP3247355A4 (en) 2015-01-23 2018-06-13 Akebia Therapeutics, Inc. Solid forms of 2-(5-(3-fluorophenyl)-3-hydroxypicolinamido)acetic acid, compositions, and uses thereof
CU20170126A7 (es) 2015-04-01 2018-07-05 Akebia Therapeutics Inc Composiciones y métodos para tratar anemia
CN105130888A (zh) * 2015-10-09 2015-12-09 中国药科大学 炔基吡啶类脯氨酰羟化酶抑制剂、其制备方法和医药用途
WO2019217550A1 (en) 2018-05-09 2019-11-14 Akebia Therapeutics, Inc. Process for preparing 2-[[5-(3-chlorophenyl)-3-hydroxypyridine-2-carbonyl]amino]acetic acid
US11524939B2 (en) 2019-11-13 2022-12-13 Akebia Therapeutics, Inc. Solid forms of {[5-(3-chlorophenyl)-3-hydroxypyridine-2-carbonyl]amino} acetic acid

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0541042A1 (de) * 1991-11-05 1993-05-12 Hoechst Aktiengesellschaft Pyridin-2,4- und 2,5-dicarbonsäureamide und deren Derivate, Verfahren zu ihrer Herstellung sowie deren Verwendung als Arzneimittel
TW352384B (en) * 1992-03-24 1999-02-11 Hoechst Ag Sulfonamido- or sulfonamidocarbonylpyridine-2-carboxamides, process for their preparation and their use as pharmaceuticals

Also Published As

Publication number Publication date
HK1011973A1 (en) 1999-07-23
CZ73495A3 (en) 1995-11-15
FI951387L (fi) 1995-09-26
ZA952409B (en) 1995-11-28
FI951387A7 (fi) 1995-09-26
AU1504395A (en) 1995-10-05
JPH07278110A (ja) 1995-10-24
FI951387A0 (fi) 1995-03-23
DE4410480A1 (de) 1995-09-28
HUT72598A (en) 1996-05-28
NO951149L (no) 1995-09-26
KR950032126A (ko) 1995-12-20
ES2146676T3 (es) 2000-08-16
PT673932E (pt) 2000-09-29
EP0673932A1 (de) 1995-09-27
AU688450B2 (en) 1998-03-12
PL307847A1 (en) 1995-10-02
EP0673932B1 (de) 2000-06-07
CZ289536B6 (cs) 2002-02-13
GR3033706T3 (en) 2000-10-31
DE59508440D1 (de) 2000-07-13
PL180678B1 (pl) 2001-03-30
NO951149D0 (no) 1995-03-24
US5620996A (en) 1997-04-15
DK0673932T3 (da) 2000-09-18
NZ270784A (en) 1997-02-24
ATE193702T1 (de) 2000-06-15
CA2145475A1 (en) 1995-09-26

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Legal Events

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MM1K Lapsed by not paying the annual fees

Free format text: LAPSED IN SEPTEMBER 2003