HUT60742A - Method for producing imidqzo-benzodiazepine-2-(1h)-one derivatives and pharmaceutical preparatives containing them - Google Patents

Method for producing imidqzo-benzodiazepine-2-(1h)-one derivatives and pharmaceutical preparatives containing them

Info

Publication number
HUT60742A
HUT60742A HU913076A HU307691A HUT60742A HU T60742 A HUT60742 A HU T60742A HU 913076 A HU913076 A HU 913076A HU 307691 A HU307691 A HU 307691A HU T60742 A HUT60742 A HU T60742A
Authority
HU
Hungary
Prior art keywords
alkyl
benzodiazepine
imidqzo
derivatives
producing
Prior art date
Application number
HU913076A
Other languages
Hungarian (hu)
Other versions
HU913076D0 (en
HU207322B (en
Inventor
Michael Joseph Kukla
Henry Joseph Breslin
Alfons Herman Marg Raeymaekers
Gelder Josephus Ludovicus Van
Paul Adriaan Jan Janssen
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Priority claimed from HU90896A external-priority patent/HU204831B/en
Publication of HU913076D0 publication Critical patent/HU913076D0/en
Publication of HUT60742A publication Critical patent/HUT60742A/en
Publication of HU207322B publication Critical patent/HU207322B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/06—Peri-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Imidazo-benzodiazepine derivs. of formula (I), their pharmaceutically acceptable acid addn. salts and their stereochemically isomeric forms are new. R1 = 1-6C alkyl (opt substd. by aryl or 3-6C cycloalkyl), 3-6C alkenyl, 3-6C alkynyl or 3-6C cycloalkyl; R2 and R3 = H or 1-6C alkyl; R4 and R5 = H, 1-6C alkyl, halo, CN, NO2, CF3, OH, 1-6C alkoxy, NH2 or mono- or di-(1-6C alkyl) amino; aryl = phenyl opt. substd. by 1-3 of 1-6C alkyl, halo, OH, 1-6C alkoxy, NH2, NO2 or CF3.
HU913076A 1989-09-08 1990-02-22 Process for producing imidazo-benzodiazepin-2/1h/-one derivatives and pharmaceutical compositions containing them HU207322B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB898920354A GB8920354D0 (en) 1989-09-08 1989-09-08 Antiviral tetrahydroimidazo(1,4)benzodiazepin-2-thiones
HU90896A HU204831B (en) 1989-02-23 1990-02-22 Process for producing imidazobenzodiazepine derivatives with antiviral effect and pharmaceutical compositions comprising same

Publications (3)

Publication Number Publication Date
HU913076D0 HU913076D0 (en) 1992-10-28
HUT60742A true HUT60742A (en) 1992-10-28
HU207322B HU207322B (en) 1993-03-29

Family

ID=10662764

Family Applications (1)

Application Number Title Priority Date Filing Date
HU913076A HU207322B (en) 1989-09-08 1990-02-22 Process for producing imidazo-benzodiazepin-2/1h/-one derivatives and pharmaceutical compositions containing them

Country Status (4)

Country Link
CS (1) CS9000854A3 (en)
GB (1) GB8920354D0 (en)
HU (1) HU207322B (en)
RU (1) RU2024523C1 (en)

Also Published As

Publication number Publication date
RU2024523C1 (en) 1994-12-15
GB8920354D0 (en) 1989-10-25
CS275171B2 (en) 1992-02-19
HU913076D0 (en) 1992-10-28
HU207322B (en) 1993-03-29
CS9000854A3 (en) 1992-02-19

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Legal Events

Date Code Title Description
HMM4 Cancellation of final prot. due to non-payment of fee