FI951370A - Tiatsolidinin ja oksatsolidinin johdannaiset, niiden valmistus ja lääkinnällinen käyttö - Google Patents

Tiatsolidinin ja oksatsolidinin johdannaiset, niiden valmistus ja lääkinnällinen käyttö Download PDF

Info

Publication number
FI951370A
FI951370A FI951370A FI951370A FI951370A FI 951370 A FI951370 A FI 951370A FI 951370 A FI951370 A FI 951370A FI 951370 A FI951370 A FI 951370A FI 951370 A FI951370 A FI 951370A
Authority
FI
Finland
Prior art keywords
thiazolidine
preparation
medical use
oxazolidine derivatives
oxazolidine
Prior art date
Application number
FI951370A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI951370A0 (fi
Inventor
Takashi Fujita
Takao Yoshioka
Hiroaki Yanagisawa
Hiroaki Fujiwara
Hiroyoshi Horikoshi
Minoru Oguchi
Kunio Wada
Koichi Fujimoto
Original Assignee
Sankyo Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankyo Co filed Critical Sankyo Co
Publication of FI951370A0 publication Critical patent/FI951370A0/fi
Publication of FI951370A publication Critical patent/FI951370A/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/34—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
FI951370A 1994-03-23 1995-03-23 Tiatsolidinin ja oksatsolidinin johdannaiset, niiden valmistus ja lääkinnällinen käyttö FI951370A (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP5154194 1994-03-23

Publications (2)

Publication Number Publication Date
FI951370A0 FI951370A0 (fi) 1995-03-23
FI951370A true FI951370A (fi) 1995-09-24

Family

ID=12889893

Family Applications (1)

Application Number Title Priority Date Filing Date
FI951370A FI951370A (fi) 1994-03-23 1995-03-23 Tiatsolidinin ja oksatsolidinin johdannaiset, niiden valmistus ja lääkinnällinen käyttö

Country Status (15)

Country Link
US (2) US5578620A (zh)
EP (1) EP0678511A3 (zh)
KR (1) KR950032187A (zh)
CN (1) CN1065532C (zh)
AU (1) AU682435B2 (zh)
CA (1) CA2145257A1 (zh)
CZ (1) CZ283938B6 (zh)
FI (1) FI951370A (zh)
HU (1) HUT71231A (zh)
ID (1) ID23600A (zh)
IL (1) IL113084A (zh)
NO (1) NO303782B1 (zh)
NZ (1) NZ270793A (zh)
TW (1) TW363959B (zh)
ZA (1) ZA952383B (zh)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5925656A (en) * 1995-04-10 1999-07-20 Dr. Reddy's Research Foundation Compounds having antidiabetic, hypolipidemic, antihypertensive properties, process for their preparation and pharmaceutical compositions containing them
CZ293016B6 (cs) * 1995-06-01 2004-01-14 Sankyo Company Limited Benzimidazolové deriváty a farmaceutické prostředky s jejich obsahem
EP0783888A1 (en) 1995-12-26 1997-07-16 Sankyo Company Limited Use of troglitazone and related thiazolidinediones in the manufacture of a medicament for the treatment and prophylaxis of osteoporosis
EP0801063B1 (en) * 1996-04-09 2003-01-15 Dr. Reddy's Laboratories Ltd. Thiazolidinedione derivatives having antidiabetic, hypolipidaemic, antihypertensive properties, process for their preparation and pharmaceutical compositions containing them
US5889025A (en) * 1996-05-06 1999-03-30 Reddy's Research Foundation Antidiabetic compounds having hypolipidaemic, antihypertensive properties, process for their preparation and pharmaceutical compositions containing them
US5801173A (en) * 1996-05-06 1998-09-01 Dr. Reddy's Research Foundation Heterocyclic compounds having antidiabetic, hypolipidaemic, antihypertensive properties, process for their preparation and pharmaceutical compositions containing them
US5919782A (en) * 1996-05-06 1999-07-06 Dr. Reddy's Research Foundation Heterocyclic compounds having antidiabetic, hypolipidaemic, antihypertensive properties, process for their preparation and pharmaceutical compositions containing them
ZA973848B (en) * 1996-05-06 1997-12-02 Reddy Research Foundation Novel heterocyclic compounds having antidiabetic, hypolipidaemic, antihypertensive properties, process for their preparation and pharmaceutical compositions containing them.
US6114526A (en) * 1996-07-01 2000-09-05 Dr. Reddy's Research Foundation Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them and their use in the treatment of diabetes and related diseases
US5885997A (en) * 1996-07-01 1999-03-23 Dr. Reddy's Research Foundation Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them and their use in the treatment of diabetes and related diseases
BR9711098B1 (pt) * 1996-07-01 2011-10-04 compostos heterocìclicos, processo para sua preparação e composições farmacêuticas contendo os mesmos e seu uso no tratamento de diabetes e doenças relacionadas.
US6372750B2 (en) 1996-07-01 2002-04-16 Dr. Reddy's Research Foundation Heterocyclic compounds, process for their preparation and pharmaceutical compounds containing them and their use in the treatment of diabetes and related diseases
USRE39266E1 (en) * 1996-07-01 2006-09-05 Dr. Reddy's Laboratories, Limited Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them and their use in the treatment of diabetes and related diseases
DK0930076T3 (da) * 1996-07-15 2005-01-31 Sankyo Co Farmaceutiske præparater omfattende CS-866 og insulinresistensforbedrende midler og deres anvendelse i behandlingen af arteriosclerose og xanthom
TW577875B (en) * 1997-01-31 2004-03-01 Shionogi & Co Pyrrolidine derivatives with inhibitory activity for phospholipase A2
US6313113B1 (en) * 1997-04-15 2001-11-06 Reddy-Cheminor, Inc. Heterocyclic compounds having antidiabetic, hypolipidemic and antihypertensive properties, process for their preparation and pharmaceutical compositions containing them
AU2930797A (en) * 1997-05-02 1997-11-19 Dr. Reddy's Research Foundation Novel antidiabetic compounds having hypolipidaemic, antihypertensive properties, process for their preparation and pharmaceutical compositions containing them
AU7109798A (en) * 1997-12-02 1998-10-30 Dr. Reddy's Research Foundation Substituted thiazolidinedione and oxazolidinedione having antidiabetic, hypol ipidemia and antihypertensive properties
US6436914B1 (en) 1998-06-30 2002-08-20 Bristol-Myers Squibb Company 2-hydroxy-3—(4-hydroxy-3-sulfonamidophenyl)—propylamines useful as beta 3 adrenergic agonists
SK632003A3 (en) 2000-07-13 2003-06-03 Lilly Co Eli Beta3 adrenergic agonists
US6537994B2 (en) 2000-07-17 2003-03-25 Wyeth Heterocyclic β3 adrenergic receptor agonists
US6395762B1 (en) 2000-07-17 2002-05-28 American Home Products Corporation Phenyl amino squarate and thiadiazole dioxide beta-3 adrenergic receptor agonists
US6465501B2 (en) 2000-07-17 2002-10-15 Wyeth Azolidines as β3 adrenergic receptor agonists
US6451814B1 (en) 2000-07-17 2002-09-17 Wyeth Heterocyclic β-3 adrenergic receptor agonists
US6458817B1 (en) 2000-07-17 2002-10-01 Wyeth Substituted arylsulfides, arylsulfoxides and arylsulfones as beta-3 adrenergic receptor agonists
US6498170B2 (en) 2000-07-17 2002-12-24 Wyeth Cyclamine sulfonamides as β-3 adrenergic receptor agonists
US6514991B2 (en) 2000-07-17 2003-02-04 Wyeth Phenyl-oxo-tetrahydroquinolin-3-yl beta-3 adrenergic receptor agonists
US6410734B1 (en) 2000-07-17 2002-06-25 Wyeth 2-substituted thiazolidinones as beta-3 adrenergic receptor agonists
US6525202B2 (en) 2000-07-17 2003-02-25 Wyeth Cyclic amine phenyl beta-3 adrenergic receptor agonists
US6509358B2 (en) 2000-07-17 2003-01-21 Wyeth Piperidino-phenyl amino squarate and thiadiazole dioxide beta-3 adrenergic receptor agonists
US6506901B2 (en) 2000-07-17 2003-01-14 Wyeth Substituted 2-(S)-hydroxy-3-(piperidin-4-yl-methylamino)-propyl ethers and substituted 2-aryl-2-(R)-hydroxy-1-(piperidin-4-yl-methyl)-ethylamine β-3 adrenergic receptor agonists
US6444685B1 (en) 2000-07-17 2002-09-03 Wyeth N-(4-sulfonylaryl)Cyclylamine 2-hydroxyethylamines as beta-3 adrenergic receptor agonists
EP1341759B1 (en) 2000-11-10 2006-06-14 Eli Lilly And Company 3-substituted oxindole beta 3 agonists
WO2002094820A1 (en) * 2001-05-23 2002-11-28 Eli Lilly And Company Crystalline salts of 2-(4-{2-[2-hydroxy-3-(2-thiophen-2-yl-phenoxy)-propylamino]-2-methyl-propyl}-phenoxy)-nicotinonitrile
ATE340794T1 (de) 2001-08-14 2006-10-15 Lilly Co Eli Indol derivate als beta-3-adrenerge agonisten zur behandlung von typ 2 diabetes
EP1444224B1 (en) 2001-08-14 2006-05-03 Eli Lilly And Company 3-substituted oxindole beta-3 agonists
US7205407B2 (en) 2001-11-20 2007-04-17 Eli Lilly And Company 3-Substituted oxindole β3 agonists
AU2002353844A1 (en) 2001-11-20 2003-06-10 Eli Lilly And Company Beta 3 adrenergic agonists
EP1467733A1 (en) 2002-01-11 2004-10-20 Eli Lilly And Company 2-oxo-benzimidazolyl substituted ethanolamine derivatives and their use as beta3 agonists
WO2006041921A2 (en) * 2004-10-05 2006-04-20 Auspex Pharmaceuticals, Inc. Preparation and uses of rhodanine derivatives
ES2394349B1 (es) 2012-08-29 2013-11-04 Fundación Centro Nacional De Investigaciones Cardiovasculares Carlos Iii Uso de agonistas selectivos de receptores beta-3 adrenérgicos para el tratamiento de hipertensión pulmonar

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5522636A (en) * 1978-08-04 1980-02-18 Takeda Chem Ind Ltd Thiazoliding derivative
CA1262729A (en) * 1983-10-19 1989-11-07 Leo Alig Phenoxypropanolamines
GB8528633D0 (en) * 1985-11-21 1985-12-24 Beecham Group Plc Compounds
US4968707A (en) * 1987-06-10 1990-11-06 Pfizer Inc. Oxazolidin-2-one derivatives as hypoglycemic agents
US5260445A (en) * 1987-09-04 1993-11-09 Beecham Group P.L.C. 2,4-thiazolidinediones
GB9017218D0 (en) * 1990-08-06 1990-09-19 Beecham Group Plc Novel compounds
GB9023583D0 (en) * 1990-10-30 1990-12-12 Beecham Group Plc Novel compounds
GB9023584D0 (en) * 1990-10-30 1990-12-12 Beecham Group Plc Novel compounds
JP3053490B2 (ja) * 1991-02-25 2000-06-19 杏林製薬株式会社 チアゾリジン−２，４−ジオン誘導体とその塩及び製造法
FR2680512B1 (fr) * 1991-08-20 1995-01-20 Adir Nouveaux derives de 2,4-thiazolidinedione, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
NO179246C (no) * 1991-11-20 1996-09-04 Sankyo Co Aromatiske amino-alkoholderivater og mellomprodukter til fremstilling derav
CZ287027B6 (en) * 1992-08-31 2000-08-16 Sankyo Co Oxazolidine derivatives, process of their preparation and pharmaceutical preparations containing thereof
JPH072848A (ja) * 1993-04-23 1995-01-06 Sankyo Co Ltd モルホリンおよびチオモルホリン誘導体

Also Published As

Publication number Publication date
TW363959B (en) 1999-07-11
IL113084A (en) 1999-01-26
US5578620A (en) 1996-11-26
HUT71231A (en) 1995-11-28
CA2145257A1 (en) 1995-09-24
CN1065532C (zh) 2001-05-09
NZ270793A (en) 1996-02-27
NO951095D0 (no) 1995-03-22
US5688823A (en) 1997-11-18
ID23600A (id) 1995-11-30
CN1132750A (zh) 1996-10-09
FI951370A0 (fi) 1995-03-23
AU1501695A (en) 1995-10-05
CZ283938B6 (cs) 1998-07-15
NO303782B1 (no) 1998-08-31
AU682435B2 (en) 1997-10-02
EP0678511A2 (en) 1995-10-25
ZA952383B (en) 1995-12-14
HU9500849D0 (en) 1995-05-29
NO951095L (no) 1995-09-25
KR950032187A (ko) 1995-12-20
EP0678511A3 (en) 1998-06-10
IL113084A0 (en) 1995-06-29
CZ73995A3 (en) 1995-12-13

Similar Documents

Publication Publication Date Title
FI951370A (fi) Tiatsolidinin ja oksatsolidinin johdannaiset, niiden valmistus ja lääkinnällinen käyttö
FI955235A (fi) Oksatsolidiinionijohdannaiset, niiden valmistus ja käyttö
FI955051A (fi) Heterosyklisiä yhdisteitä ja niiden valmistus ja käyttö
FI953479A (fi) 1-aryylipyrimidiinijohdannaiset ja niiden farmaseuttinen käyttö
DE10199018I2 (de) Thiazolidindion-Derivate, deren Herstellung und Anwendung.
BR9509774A (pt) Fralda descartável
BR9612678A (pt) Seringa descartável
DE69529780D1 (de) Wegwerfwindel
DE69525077D1 (de) Wegwerf-windel
FI956273A (fi) Optisesti aktiivinen bentsotiepiinijohdannainen, sen valmistus ja käyttö
FI101382B (fi) Dihydroksipropyylisulfoetyyliselluloosia, niiden valmistus ja käyttö
FI955679A (fi) Piperidiinijohdannaisia, niiden valmistus ja käyttö
FI961977A0 (fi) N-substituoidut atsabisykloalkaanijohdannaiset, niiden valmistus ja käyttö
EE9900135A (et) N-(2-bensotiasolüül)-1-piperidiinetaanamiini derivaadid, nende valmistamine ja kasutamine raviks
DE69123958D1 (de) Wegwerfwerkzeug und -einsatz
FI956251A0 (fi) 1-okso-2-(fenyylisulfonyyliamino)pentyylipiperidiinijohdannaiset, niiden valmistus ja terapeuttinen käyttö
FI894323A0 (fi) Antimikrobiaalinen ainekoostumus, menetelmä ja käyttö
FI971990A0 (fi) Oksatsolyyli- ja tiatsolyyli-imidatso-bentso- ja tienodiatsepiineja ja niiden käyttö lääkkeinä
EE03441B1 (et) 5-naftalen-1-üül-1,3-dioksaani derivaadid, nende valmistamine ja terapeutiline kasutamine
NO953002L (no) Anvendelse av eliprodil og enantiomerer derav for fremstilling av medisinske preparater
DE69517491D1 (de) Wegwerfwindel
EE9900560A (et) 5-naftaleen-1-üül-1,3-dioksaani derivaadid, nende valmistamine ja terapeutiline kasutamine
FI945314A0 (fi) Tetrasolijohdannaiset, niiden valmistus ja käytt¦
FI950021A0 (fi) Tienopyrimidiinijohdannaiset, niiden valmistus ja käyttö
FI940541A0 (fi) Lyfttransportanordning foer foerflyttning och tvaettning av en roerelsehindrad patient