FI950670A - 1-/2-(1H-inden-3-yyli)etyyli/-4-(naftalen-1-yyli)piperatsiinijohdannaiset, niiden valmistus ja terapeuttinen käyttö - Google Patents

1-/2-(1H-inden-3-yyli)etyyli/-4-(naftalen-1-yyli)piperatsiinijohdannaiset, niiden valmistus ja terapeuttinen käyttö Download PDF

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Publication number
FI950670A
FI950670A FI950670A FI950670A FI950670A FI 950670 A FI950670 A FI 950670A FI 950670 A FI950670 A FI 950670A FI 950670 A FI950670 A FI 950670A FI 950670 A FI950670 A FI 950670A
Authority
FI
Finland
Prior art keywords
inden
naphthalen
ethyl
preparation
therapeutic use
Prior art date
Application number
FI950670A
Other languages
English (en)
Swedish (sv)
Other versions
FI950670A0 (fi
Inventor
Philippe Manoury
Daniel Obitz
Michel Peynot
Mireille Sevrin
Pascal George
Original Assignee
Synthelabo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synthelabo filed Critical Synthelabo
Publication of FI950670A0 publication Critical patent/FI950670A0/fi
Publication of FI950670A publication Critical patent/FI950670A/fi

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
    • C07D295/027—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring
    • C07D295/033—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring with the ring nitrogen atoms directly attached to carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/096—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Addiction (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FI950670A 1994-02-16 1995-02-15 1-/2-(1H-inden-3-yyli)etyyli/-4-(naftalen-1-yyli)piperatsiinijohdannaiset, niiden valmistus ja terapeuttinen käyttö FI950670A (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9401736A FR2716193B1 (fr) 1994-02-16 1994-02-16 Dérivés de 1[2-(1h-inden-3-yl)ethyl]-4-(naphtalen-1-yl)piperazine, leur préparation et leur application en thérapeutique.

Publications (2)

Publication Number Publication Date
FI950670A0 FI950670A0 (fi) 1995-02-15
FI950670A true FI950670A (fi) 1995-08-17

Family

ID=9460124

Family Applications (1)

Application Number Title Priority Date Filing Date
FI950670A FI950670A (fi) 1994-02-16 1995-02-15 1-/2-(1H-inden-3-yyli)etyyli/-4-(naftalen-1-yyli)piperatsiinijohdannaiset, niiden valmistus ja terapeuttinen käyttö

Country Status (18)

Country Link
US (1) US5530002A (fi)
EP (1) EP0668273A1 (fi)
JP (1) JPH07252243A (fi)
KR (1) KR950032160A (fi)
CN (1) CN1112554A (fi)
AU (1) AU680327B2 (fi)
CA (1) CA2142535A1 (fi)
CZ (1) CZ39395A3 (fi)
FI (1) FI950670A (fi)
FR (1) FR2716193B1 (fi)
HU (1) HUT71898A (fi)
IL (1) IL112661A0 (fi)
NO (1) NO304230B1 (fi)
NZ (1) NZ270500A (fi)
PL (1) PL307286A1 (fi)
RU (1) RU95102147A (fi)
SK (1) SK20795A3 (fi)
ZA (1) ZA951235B (fi)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2737724B1 (fr) * 1995-08-09 1997-09-05 Synthelabo Derives de 1-[2-(2,3-dihydro-1h-inden-1-yl)ethyl]-4- (naphtalen-1-yl) piperazine, leur preparation et leur application en therapeutique
FR2737723B1 (fr) * 1995-08-09 1997-09-05 Synthelabo Derives de 1-(2-(1h-inden-3-yl)ethyl)-4-(naphtalen-1-yl)- piperazine, leur preparation et leur application en therapeutique
US7189753B1 (en) 1997-11-06 2007-03-13 Cady Roger K Preemptive prophylaxis of migraine
DE602005019098D1 (de) * 2004-12-21 2010-03-11 Hoffmann La Roche Tetralin- und indanderivate und deren anwendungen

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4130646A (en) * 1975-07-25 1978-12-19 E. R. Squibb & Sons, Inc. 1,2,3,4-Tetrahydro-2-((4-(phenyl)-1-piperazinyl)methyl)-1-naphthalenols and derivatives and analogs thereof
US4845221A (en) * 1988-04-15 1989-07-04 American Home Products Corporation Serotonergic substituted piperazinyl tetralins
FR2670491B1 (fr) * 1990-12-14 1993-02-05 Adir Nouvelles piperazines 1,4-disubstituees, leur procede de preparation et les compositions pharmaceutiques les renfermant.
IT1255178B (it) * 1992-06-26 1995-10-20 Pierrel Spa N(eter0)-aril-n(etero)-tetralinalchil piperazine aventi attivita' serotoninergica,dopaminergica e adrenergica

Also Published As

Publication number Publication date
CA2142535A1 (en) 1995-08-17
HUT71898A (en) 1996-02-28
RU95102147A (ru) 1996-12-10
AU1224495A (en) 1995-08-24
NZ270500A (en) 1996-02-27
CZ39395A3 (en) 1995-10-18
PL307286A1 (en) 1995-08-21
NO950560L (no) 1995-08-17
US5530002A (en) 1996-06-25
FR2716193A1 (fr) 1995-08-18
SK20795A3 (en) 1995-09-13
JPH07252243A (ja) 1995-10-03
AU680327B2 (en) 1997-07-24
CN1112554A (zh) 1995-11-29
NO304230B1 (no) 1998-11-16
KR950032160A (ko) 1995-12-20
EP0668273A1 (fr) 1995-08-23
FI950670A0 (fi) 1995-02-15
NO950560D0 (no) 1995-02-15
IL112661A0 (en) 1995-05-26
HU9500453D0 (en) 1995-03-28
ZA951235B (en) 1996-01-18
FR2716193B1 (fr) 1996-04-05

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