FI946173A - Menetelmä lääkeaineiden antotehon parantamiseksi muunnettujen saponiinien avulla - Google Patents

Menetelmä lääkeaineiden antotehon parantamiseksi muunnettujen saponiinien avulla Download PDF

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Publication number
FI946173A
FI946173A FI946173A FI946173A FI946173A FI 946173 A FI946173 A FI 946173A FI 946173 A FI946173 A FI 946173A FI 946173 A FI946173 A FI 946173A FI 946173 A FI946173 A FI 946173A
Authority
FI
Finland
Prior art keywords
methods
improve drug
drug uptake
modified saponins
saponins
Prior art date
Application number
FI946173A
Other languages
English (en)
Swedish (sv)
Other versions
FI946173A0 (fi
Inventor
Charlotte A Kensil
Sean Soltysik
Dante J Marciani
Original Assignee
Cambridge Biotech Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cambridge Biotech Corp filed Critical Cambridge Biotech Corp
Publication of FI946173A0 publication Critical patent/FI946173A0/fi
Publication of FI946173A publication Critical patent/FI946173A/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J63/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by expansion of only one ring by one or two atoms
    • C07J63/008—Expansion of ring D by one atom, e.g. D homo steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/28—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/28—Steroids, e.g. cholesterol, bile acids or glycyrrhetinic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55577—Saponins; Quil A; QS21; ISCOMS

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Steroid Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FI946173A 1992-07-02 1994-12-30 Menetelmä lääkeaineiden antotehon parantamiseksi muunnettujen saponiinien avulla FI946173A (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/906,870 US5273965A (en) 1992-07-02 1992-07-02 Methods for enhancing drug delivery with modified saponins
PCT/US1993/006348 WO1994001118A1 (en) 1992-07-02 1993-07-01 Methods for enhancing drug delivery with modified saponins

Publications (2)

Publication Number Publication Date
FI946173A0 FI946173A0 (fi) 1994-12-30
FI946173A true FI946173A (fi) 1995-02-15

Family

ID=25423119

Family Applications (1)

Application Number Title Priority Date Filing Date
FI946173A FI946173A (fi) 1992-07-02 1994-12-30 Menetelmä lääkeaineiden antotehon parantamiseksi muunnettujen saponiinien avulla

Country Status (11)

Country Link
US (2) US5273965A (fi)
EP (1) EP0658111B1 (fi)
JP (1) JP3684370B2 (fi)
AU (1) AU687005B2 (fi)
BR (1) BR9306594A (fi)
CA (1) CA2139437A1 (fi)
DE (1) DE69326772T2 (fi)
FI (1) FI946173A (fi)
HU (1) HUT73814A (fi)
MX (1) MX9303977A (fi)
WO (1) WO1994001118A1 (fi)

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US5650398A (en) * 1992-07-02 1997-07-22 Cambridge Biotech Corporation Drug delivery enhancement via modified saponins
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Also Published As

Publication number Publication date
US5273965A (en) 1993-12-28
HUT73814A (en) 1996-09-30
MX9303977A (es) 1994-04-29
EP0658111A4 (en) 1996-02-07
AU687005B2 (en) 1998-02-19
HU9500001D0 (en) 1995-03-28
WO1994001118A1 (en) 1994-01-20
DE69326772T2 (de) 2000-06-29
JPH07509440A (ja) 1995-10-19
EP0658111A1 (en) 1995-06-21
CA2139437A1 (en) 1994-01-20
BR9306594A (pt) 1998-12-08
AU4664993A (en) 1994-01-31
DE69326772D1 (de) 1999-11-18
US5443829A (en) 1995-08-22
FI946173A0 (fi) 1994-12-30
EP0658111B1 (en) 1999-10-13
JP3684370B2 (ja) 2005-08-17

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