FI945811A - Des-Tyr-dynorfiinianalogeja - Google Patents

Des-Tyr-dynorfiinianalogeja Download PDF

Info

Publication number
FI945811A
FI945811A FI945811A FI945811A FI945811A FI 945811 A FI945811 A FI 945811A FI 945811 A FI945811 A FI 945811A FI 945811 A FI945811 A FI 945811A FI 945811 A FI945811 A FI 945811A
Authority
FI
Finland
Prior art keywords
dynorfinanaloger
tyr
des
Prior art date
Application number
FI945811A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI945811A0 (fi
Inventor
Nancy M Lee
Horace H Loh
Akira E Takemori
Original Assignee
Des Tyr Dynorphin Partnership
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Des Tyr Dynorphin Partnership filed Critical Des Tyr Dynorphin Partnership
Publication of FI945811A0 publication Critical patent/FI945811A0/fi
Publication of FI945811A publication Critical patent/FI945811A/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/665—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans derived from pro-opiomelanocortin, pro-enkephalin or pro-dynorphin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K17/00—Carrier-bound or immobilised peptides; Preparation thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Biophysics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Addiction (AREA)
  • Toxicology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
FI945811A 1992-06-12 1994-12-09 Des-Tyr-dynorfiinianalogeja FI945811A (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US89792092A 1992-06-12 1992-06-12
PCT/US1993/005161 WO1993025217A1 (fr) 1992-06-12 1993-06-01 Analogues de dynophine des-tyr

Publications (2)

Publication Number Publication Date
FI945811A0 FI945811A0 (fi) 1994-12-09
FI945811A true FI945811A (fi) 1995-02-06

Family

ID=25408662

Family Applications (1)

Application Number Title Priority Date Filing Date
FI945811A FI945811A (fi) 1992-06-12 1994-12-09 Des-Tyr-dynorfiinianalogeja

Country Status (11)

Country Link
EP (1) EP0652765A4 (fr)
JP (1) JPH08501075A (fr)
KR (1) KR950701818A (fr)
AU (1) AU4399093A (fr)
CA (1) CA2137916A1 (fr)
CZ (1) CZ281630B6 (fr)
FI (1) FI945811A (fr)
HU (1) HUT70160A (fr)
NO (1) NO944778L (fr)
RU (1) RU95106651A (fr)
WO (1) WO1993025217A1 (fr)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5482930A (en) * 1993-06-09 1996-01-09 The Regents Of The University Of California Anti-inflammatory composition and method with des-Tyr dynorphin and analogues
US7220737B1 (en) 1997-09-04 2007-05-22 Novoneuron, Inc Noribogaine in the treatment of pain and drug addiction
EP2246058A1 (fr) 1997-09-04 2010-11-03 Novoneuron, Inc. Noribogain utilisée pour le traitement de la douleur et de la toxicomanie
US6437092B1 (en) 1998-11-06 2002-08-20 Conjuchem, Inc. Conjugates of opioids and endogenous carriers
US6887470B1 (en) 1999-09-10 2005-05-03 Conjuchem, Inc. Protection of endogenous therapeutic peptides from peptidase activity through conjugation to blood components
AU765753B2 (en) 1999-05-17 2003-09-25 Conjuchem Biotechnologies Inc. Protection of endogenous therapeutic peptides from peptidase activity through conjugation to blood components
US6849714B1 (en) 1999-05-17 2005-02-01 Conjuchem, Inc. Protection of endogenous therapeutic peptides from peptidase activity through conjugation to blood components
US7601691B2 (en) 1999-05-17 2009-10-13 Conjuchem Biotechnologies Inc. Anti-obesity agents
US6706892B1 (en) 1999-09-07 2004-03-16 Conjuchem, Inc. Pulmonary delivery for bioconjugation
EP1355941A2 (fr) 2001-02-02 2003-10-29 ConjuChem, Inc. Derives du facteur de liberation de l'hormone de croissance de longue duree
CA2436399A1 (fr) 2001-02-16 2002-08-29 Conjuchem Inc. Peptide 2 de type glucagon (glp-2) de longue duree utilise dans le traitement des maladies et troubles gastro-intestinaux
US8362007B1 (en) 2010-05-11 2013-01-29 Demerx, Inc. Substituted noribogaine
US8765737B1 (en) 2010-05-11 2014-07-01 Demerx, Inc. Methods and compositions for preparing and purifying noribogaine
US9394294B2 (en) 2010-05-11 2016-07-19 Demerx, Inc. Methods and compositions for preparing and purifying noribogaine
US9586954B2 (en) 2010-06-22 2017-03-07 Demerx, Inc. N-substituted noribogaine prodrugs
US8741891B1 (en) 2010-06-22 2014-06-03 Demerx, Inc. N-substituted noribogaine prodrugs
US8802832B2 (en) 2010-06-22 2014-08-12 Demerx, Inc. Compositions comprising noribogaine and an excipient to facilitate transport across the blood brain barrier
US8637648B1 (en) 2010-06-22 2014-01-28 Demerx, Inc. Compositions comprising noribogaine and an excipient to facilitate transport across the blood brain barrier
US9358237B2 (en) 2010-07-23 2016-06-07 Demerx, Inc. Noribogaine compositions
EP2481740B1 (fr) 2011-01-26 2015-11-04 DemeRx, Inc. Procédés et compositions pour préparer de la noribogaïne à partir de voacangine
US9617274B1 (en) 2011-08-26 2017-04-11 Demerx, Inc. Synthetic noribogaine
WO2013085922A1 (fr) 2011-12-09 2013-06-13 Demerx, Inc. Esters phosphoriques de noribogaïne
US9150584B2 (en) 2012-01-25 2015-10-06 Demerx, Inc. Indole and benzofuran fused isoquinuclidene derivatives and processes for preparing them
US8877921B2 (en) 2012-01-25 2014-11-04 Demerx, Inc. Synthetic voacangine
JP2016508979A (ja) 2012-12-20 2016-03-24 デメレックス， インコーポレイテッド 置換ノルイボガイン
US9045481B2 (en) 2012-12-20 2015-06-02 Demerx, Inc. Substituted noribogaine
US8940728B2 (en) 2012-12-20 2015-01-27 Demerx, Inc. Substituted noribogaine
US10428115B2 (en) 2013-05-24 2019-10-01 Arizona Board Of Regents On Behalf Of The University Of Arizona Dynorphin A analogs with bradykinin receptors specificity for modulation of neuropathic pain
WO2015195673A2 (fr) 2014-06-18 2015-12-23 Demerx, Inc. Dérivés d'indole et de benzofurane halogénés d'isoquinuclidène et procédés pour leur préparation.

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996006626A1 (fr) * 1994-08-26 1996-03-07 Lee Nancy M Procede analgesique utilisant des analogues de dynorphine tronques au niveau de la terminaison n

Also Published As

Publication number Publication date
RU95106651A (ru) 1996-12-27
FI945811A0 (fi) 1994-12-09
WO1993025217A1 (fr) 1993-12-23
KR950701818A (ko) 1995-05-17
NO944778L (no) 1995-02-10
CZ313194A3 (en) 1995-08-16
AU4399093A (en) 1994-01-04
CZ281630B6 (cs) 1996-11-13
HUT70160A (en) 1995-09-28
NO944778D0 (no) 1994-12-09
EP0652765A4 (fr) 1997-04-09
HU9403563D0 (en) 1995-02-28
EP0652765A1 (fr) 1995-05-17
JPH08501075A (ja) 1996-02-06
CA2137916A1 (fr) 1993-12-23

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