FI945729A - Aminosubstituoidut bentseenisulfonyyliureat ja -tioureat, menetelmä niiden valmistamiseksi ja niiden käyttö farmaseuttisina aineina - Google Patents
Aminosubstituoidut bentseenisulfonyyliureat ja -tioureat, menetelmä niiden valmistamiseksi ja niiden käyttö farmaseuttisina aineina Download PDFInfo
- Publication number
- FI945729A FI945729A FI945729A FI945729A FI945729A FI 945729 A FI945729 A FI 945729A FI 945729 A FI945729 A FI 945729A FI 945729 A FI945729 A FI 945729A FI 945729 A FI945729 A FI 945729A
- Authority
- FI
- Finland
- Prior art keywords
- amino
- processes
- preparation
- pharmaceutical agents
- thiourea compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/50—Compounds containing any of the groups, X being a hetero atom, Y being any atom
- C07C311/52—Y being a hetero atom
- C07C311/54—Y being a hetero atom either X or Y, but not both, being nitrogen atoms, e.g. N-sulfonylurea
- C07C311/57—Y being a hetero atom either X or Y, but not both, being nitrogen atoms, e.g. N-sulfonylurea having sulfur atoms of the sulfonylurea groups bound to carbon atoms of six-membered aromatic rings
- C07C311/58—Y being a hetero atom either X or Y, but not both, being nitrogen atoms, e.g. N-sulfonylurea having sulfur atoms of the sulfonylurea groups bound to carbon atoms of six-membered aromatic rings having nitrogen atoms of the sulfonylurea groups bound to hydrogen atoms or to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/12—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms
- C07D295/135—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly or doubly bound nitrogen atoms with the ring nitrogen atoms and the substituent nitrogen atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C335/00—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C335/40—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of thiourea or isothiourea groups further bound to other hetero atoms
- C07C335/42—Sulfonylthioureas; Sulfonylisothioureas
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Heart & Thoracic Surgery (AREA)
- General Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Cardiology (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE4341655A DE4341655A1 (de) | 1993-12-07 | 1993-12-07 | Aminosubstituierte Benzolsulfonylharnstoffe und -thioharnstoffe, Verfahren zu ihrer Herstellung und ihre Verwendung als Pharmazeutika |
DE4341655 | 1993-12-07 |
Publications (3)
Publication Number | Publication Date |
---|---|
FI945729A0 FI945729A0 (fi) | 1994-12-05 |
FI945729A true FI945729A (fi) | 1995-06-08 |
FI107152B FI107152B (fi) | 2001-06-15 |
Family
ID=6504371
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI945729A FI107152B (fi) | 1993-12-07 | 1994-12-05 | Menetelmä uusien terapeuttisesti käyttökelpoisten aminosubstituoitujen bentseenisulfonyylitioureajohdannaisten valmistamiseksi |
Country Status (18)
Country | Link |
---|---|
US (1) | US5476850A (fi) |
EP (1) | EP0657423B1 (fi) |
JP (1) | JP3718246B2 (fi) |
KR (1) | KR100338168B1 (fi) |
CN (1) | CN1054372C (fi) |
AT (1) | ATE175192T1 (fi) |
AU (1) | AU678866B2 (fi) |
CA (1) | CA2137441C (fi) |
DE (2) | DE4341655A1 (fi) |
DK (1) | DK0657423T3 (fi) |
ES (1) | ES2127875T3 (fi) |
FI (1) | FI107152B (fi) |
GR (1) | GR3029768T3 (fi) |
HU (1) | HU219228B (fi) |
IL (1) | IL111870A (fi) |
NO (1) | NO302468B1 (fi) |
NZ (1) | NZ270062A (fi) |
ZA (1) | ZA949687B (fi) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE19503136A1 (de) * | 1995-02-01 | 1996-08-08 | Hoechst Ag | Substituierte Thiophenylsulfonylharnstoffe und -thioharnstoffe, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament |
ZA961314B (en) * | 1995-02-21 | 1996-08-27 | Hoechst Ag | Substituted benzenesulfonylureas and -thioreas processes for their preparation their use for the production of pharmaceutical preparations and medicaments containing them |
DE19832009A1 (de) | 1998-07-16 | 2000-01-20 | Hoechst Marion Roussel De Gmbh | 2,5-Substituierte Benzolsulfonylharnstoffe und -thioharnstoffe, Verfahren zu ihrer Herstellung, ihre Verwendung und sie enthaltende pharamazeutische Präparate |
US6503949B1 (en) | 1999-05-17 | 2003-01-07 | Noro Nordisk A/S | Glucagon antagonists/inverse agonists |
DE19923086A1 (de) | 1999-05-20 | 2000-11-23 | Aventis Pharma Gmbh | Cinnamoylaminoalkyl-substituierte Benzolsulfonamidderivate, Verfahren zu ihrer Herstellung, ihre Verwendung und sie enthaltende pharmazeutische Präparate |
DE10054482A1 (de) | 2000-11-03 | 2002-05-08 | Aventis Pharma Gmbh | Heteroarylacryloylaminoalkyl-substituierte Benzolsulfonamidderivate, ihre Herstellung, ihre Verwendung und sie enthaltende pharmazeutische Präparate |
DE10054481A1 (de) | 2000-11-03 | 2002-05-08 | Aventis Pharma Gmbh | Acylaminoalkyl-substituierte Benzolsulfonamidderivate, ihre Herstellung, ihre Verwendung und sie enthaltende pharmazeutische Präparate |
CN1330630C (zh) * | 2004-03-10 | 2007-08-08 | 中国药科大学 | 新的磺酰(硫)脲衍生物、其制备方法及含有它们的药物组合物 |
DE102004061017A1 (de) * | 2004-12-18 | 2006-06-22 | Sanofi-Aventis Deutschland Gmbh | Piperidinsulfonylharnstoffe und -thioharnstoffe, ihre Herstellung, ihre Verwendung und sie enthaltende pharmazeutische Präparate |
PT2164825E (pt) * | 2007-06-05 | 2014-06-24 | Sanofi Sa | Derivados de di(hetero)arilciclo-hexano, sua preparação, sua utilização e composições farmacêuticas compreendendo os mesmos |
JP2023534674A (ja) * | 2020-07-17 | 2023-08-10 | 上海森輝医薬有限公司 | スルホニル尿素誘導体及びその医薬用途 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1518874C3 (de) * | 1964-10-07 | 1975-03-13 | Farbwerke Hoechst Ag, Vormals Meister Lucius & Bruening, 6000 Frankfurt | Benzolsulfonylharnstoffe und Verfahren zu ihrer Herstellung |
DE2413514C3 (de) * | 1974-03-21 | 1982-03-04 | Hoechst Ag, 6000 Frankfurt | N-Acylaminoathylbenzolsulfonyl-N'-methylharnstoffe, Verfahren zu ihrer Herstellung und deren Verwendung |
-
1993
- 1993-12-07 DE DE4341655A patent/DE4341655A1/de not_active Withdrawn
-
1994
- 1994-12-01 AT AT94118931T patent/ATE175192T1/de active
- 1994-12-01 DK DK94118931T patent/DK0657423T3/da active
- 1994-12-01 EP EP94118931A patent/EP0657423B1/de not_active Expired - Lifetime
- 1994-12-01 ES ES94118931T patent/ES2127875T3/es not_active Expired - Lifetime
- 1994-12-01 DE DE59407559T patent/DE59407559D1/de not_active Expired - Lifetime
- 1994-12-05 FI FI945729A patent/FI107152B/fi not_active IP Right Cessation
- 1994-12-05 AU AU80213/94A patent/AU678866B2/en not_active Ceased
- 1994-12-05 US US08/353,263 patent/US5476850A/en not_active Expired - Lifetime
- 1994-12-05 IL IL11187094A patent/IL111870A/en not_active IP Right Cessation
- 1994-12-05 CN CN94119386A patent/CN1054372C/zh not_active Expired - Fee Related
- 1994-12-05 HU HU9403486A patent/HU219228B/hu not_active IP Right Cessation
- 1994-12-05 NZ NZ270062A patent/NZ270062A/xx not_active IP Right Cessation
- 1994-12-06 ZA ZA949687A patent/ZA949687B/xx unknown
- 1994-12-06 CA CA002137441A patent/CA2137441C/en not_active Expired - Fee Related
- 1994-12-06 NO NO944699A patent/NO302468B1/no not_active IP Right Cessation
- 1994-12-06 JP JP30173994A patent/JP3718246B2/ja not_active Expired - Fee Related
- 1994-12-07 KR KR1019940033038A patent/KR100338168B1/ko not_active IP Right Cessation
-
1999
- 1999-03-23 GR GR990400855T patent/GR3029768T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
CN1054372C (zh) | 2000-07-12 |
CA2137441A1 (en) | 1995-06-08 |
EP0657423A1 (de) | 1995-06-14 |
US5476850A (en) | 1995-12-19 |
AU8021394A (en) | 1995-06-15 |
HU9403486D0 (en) | 1995-02-28 |
IL111870A0 (en) | 1995-03-15 |
NZ270062A (en) | 1996-07-26 |
ZA949687B (en) | 1995-07-10 |
ATE175192T1 (de) | 1999-01-15 |
JP3718246B2 (ja) | 2005-11-24 |
KR950017942A (ko) | 1995-07-22 |
ES2127875T3 (es) | 1999-05-01 |
KR100338168B1 (ko) | 2003-02-11 |
HUT71125A (en) | 1995-11-28 |
CA2137441C (en) | 2005-10-18 |
DE59407559D1 (de) | 1999-02-11 |
NO944699D0 (no) | 1994-12-06 |
EP0657423B1 (de) | 1998-12-30 |
NO302468B1 (no) | 1998-03-09 |
NO944699L (no) | 1995-06-08 |
FI945729A0 (fi) | 1994-12-05 |
FI107152B (fi) | 2001-06-15 |
HU219228B (en) | 2001-03-28 |
AU678866B2 (en) | 1997-06-12 |
CN1111238A (zh) | 1995-11-08 |
GR3029768T3 (en) | 1999-06-30 |
DK0657423T3 (da) | 1999-07-19 |
JPH07196597A (ja) | 1995-08-01 |
IL111870A (en) | 1999-03-12 |
DE4341655A1 (de) | 1995-06-08 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MM | Patent lapsed |