MX9305312A - 2,4-diazepina aril-fusionada y hetaril-fusionada y agentes antiarritmicosde 2,4-diazocina. - Google Patents
2,4-diazepina aril-fusionada y hetaril-fusionada y agentes antiarritmicosde 2,4-diazocina.Info
- Publication number
- MX9305312A MX9305312A MX9305312A MX9305312A MX9305312A MX 9305312 A MX9305312 A MX 9305312A MX 9305312 A MX9305312 A MX 9305312A MX 9305312 A MX9305312 A MX 9305312A MX 9305312 A MX9305312 A MX 9305312A
- Authority
- MX
- Mexico
- Prior art keywords
- aryl
- fusionada
- alkyl
- hetaryl
- aralkyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/04—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D245/00—Heterocyclic compounds containing rings of more than seven members having two nitrogen atoms as the only ring hetero atoms
- C07D245/04—Heterocyclic compounds containing rings of more than seven members having two nitrogen atoms as the only ring hetero atoms condensed with carbocyclic rings or ring systems
- C07D245/06—Heterocyclic compounds containing rings of more than seven members having two nitrogen atoms as the only ring hetero atoms condensed with carbocyclic rings or ring systems condensed with one six-membered ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Abstract
La presente invención se refiere a novedosas 4,5-dihidro-1H-2,4-arilfusionado diazepinas, y a métodos y composiciones para tratar arritmiascardíacas en mamíferos empleando las 4, 5-dihidro-1H-2, 4-benzodiazepinas.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US97439692A | 1992-11-10 | 1992-11-10 | |
US2192693A | 1993-02-24 | 1993-02-24 |
Publications (1)
Publication Number | Publication Date |
---|---|
MX9305312A true MX9305312A (es) | 1995-01-31 |
Family
ID=26695257
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX9305312A MX9305312A (es) | 1992-11-10 | 1993-08-31 | 2,4-diazepina aril-fusionada y hetaril-fusionada y agentes antiarritmicosde 2,4-diazocina. |
Country Status (15)
Country | Link |
---|---|
EP (1) | EP0597540B1 (es) |
JP (1) | JPH06220025A (es) |
AT (1) | ATE138916T1 (es) |
AU (1) | AU4472093A (es) |
CA (1) | CA2104060A1 (es) |
CZ (1) | CZ237393A3 (es) |
DE (1) | DE69302991D1 (es) |
FI (1) | FI934895A (es) |
HU (1) | HUT67281A (es) |
IL (1) | IL107519A0 (es) |
MX (1) | MX9305312A (es) |
NO (1) | NO934058D0 (es) |
NZ (1) | NZ248414A (es) |
SK (1) | SK124593A3 (es) |
TW (1) | TW245714B (es) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1940828B1 (en) | 2005-10-27 | 2010-08-18 | Schering Corporation | Heterocyclic aspartyl protease inhibitors |
JP5529131B2 (ja) * | 2008-08-13 | 2014-06-25 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | キマーゼ阻害薬 |
US20130116241A1 (en) * | 2011-11-09 | 2013-05-09 | Abbvie Inc. | Novel inhibitor compounds of phosphodiesterase type 10a |
KR101991429B1 (ko) | 2014-12-19 | 2019-06-20 | 주식회사 엘지화학 | 새로운 화합물 및 이를 이용한 고분자 전해질막 |
CN113840820B (zh) * | 2019-05-29 | 2024-05-03 | St制药株式会社 | 酞嗪酮化合物及其用途 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH527828A (de) * | 1967-04-13 | 1972-09-15 | Ciba Geigy Ag | Verfahren zur Herstellung von 2,4-Benzdiazepinen |
US3696093A (en) * | 1970-09-30 | 1972-10-03 | Ciba Geigy Corp | 2,4-benzodiazepines |
NZ232396A (en) * | 1989-02-10 | 1991-07-26 | Merrell Dow Pharma | 2-(diphenylalkylamino) -1,3 nn heterocyclic compounds and pharmaceutical compositions |
US5032598A (en) * | 1989-12-08 | 1991-07-16 | Merck & Co., Inc. | Nitrogens containing heterocyclic compounds as class III antiarrhythmic agents |
US5215989A (en) * | 1989-12-08 | 1993-06-01 | Merck & Co., Inc. | Nitrogen-containing heterocyclic compounds as class III antiarrhythmic agents |
TW245719B (es) * | 1990-09-10 | 1995-04-21 | Sterling Winthrop Inc |
-
1993
- 1993-08-13 CA CA002104060A patent/CA2104060A1/en not_active Abandoned
- 1993-08-16 NZ NZ248414A patent/NZ248414A/en unknown
- 1993-08-17 AU AU44720/93A patent/AU4472093A/en not_active Abandoned
- 1993-08-31 MX MX9305312A patent/MX9305312A/es not_active IP Right Cessation
- 1993-09-15 TW TW082107576A patent/TW245714B/zh active
- 1993-09-22 JP JP5236532A patent/JPH06220025A/ja not_active Withdrawn
- 1993-11-04 HU HU9303135A patent/HUT67281A/hu unknown
- 1993-11-05 FI FI934895A patent/FI934895A/fi not_active Application Discontinuation
- 1993-11-05 IL IL10751993A patent/IL107519A0/xx unknown
- 1993-11-05 CZ CZ932373A patent/CZ237393A3/cs unknown
- 1993-11-06 DE DE69302991T patent/DE69302991D1/de not_active Expired - Lifetime
- 1993-11-06 EP EP93203115A patent/EP0597540B1/en not_active Expired - Lifetime
- 1993-11-06 AT AT93203115T patent/ATE138916T1/de not_active IP Right Cessation
- 1993-11-08 SK SK1245-93A patent/SK124593A3/sk unknown
- 1993-11-09 NO NO934058A patent/NO934058D0/no unknown
Also Published As
Publication number | Publication date |
---|---|
EP0597540A1 (en) | 1994-05-18 |
TW245714B (es) | 1995-04-21 |
NO934058L (es) | 1994-05-11 |
JPH06220025A (ja) | 1994-08-09 |
FI934895A (fi) | 1994-05-11 |
CZ237393A3 (en) | 1996-08-14 |
ATE138916T1 (de) | 1996-06-15 |
DE69302991D1 (de) | 1996-07-11 |
HU9303135D0 (en) | 1994-02-28 |
SK124593A3 (en) | 1994-08-10 |
CA2104060A1 (en) | 1994-05-11 |
NO934058D0 (no) | 1993-11-09 |
IL107519A0 (en) | 1994-02-27 |
HUT67281A (en) | 1995-03-28 |
FI934895A0 (fi) | 1993-11-05 |
AU4472093A (en) | 1994-05-26 |
EP0597540B1 (en) | 1996-06-05 |
NZ248414A (en) | 1995-02-24 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG | Grant or registration | ||
MM | Annulment or lapse due to non-payment of fees |