FI943705A0 - Farmaseuttiset koostumukset - Google Patents

Farmaseuttiset koostumukset

Info

Publication number
FI943705A0
FI943705A0 FI943705A FI943705A FI943705A0 FI 943705 A0 FI943705 A0 FI 943705A0 FI 943705 A FI943705 A FI 943705A FI 943705 A FI943705 A FI 943705A FI 943705 A0 FI943705 A0 FI 943705A0
Authority
FI
Finland
Prior art keywords
pharmaceutical compositions
stabiliser
interferon
buffer
aqueous solution
Prior art date
Application number
FI943705A
Other languages
English (en)
Swedish (sv)
Other versions
FI111222B (fi
FI943705A (fi
Inventor
Nicholas Lowther
John Douglas Allen
Colin Howens
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB939316849A external-priority patent/GB9316849D0/en
Priority claimed from GB9405879A external-priority patent/GB9405879D0/en
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of FI943705A0 publication Critical patent/FI943705A0/fi
Publication of FI943705A publication Critical patent/FI943705A/fi
Application granted granted Critical
Publication of FI111222B publication Critical patent/FI111222B/fi

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • A61K38/21Interferons [IFN]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12Carboxylic acids; Salts or anhydrides thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • A61K38/21Interferons [IFN]
    • A61K38/212IFN-alpha
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183Amino acids, e.g. glycine, EDTA or aspartame
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
FI943705A 1993-08-13 1994-08-10 Menetelmä hybridi-alfa-interferoniliuoksen valmistamiseksi FI111222B (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB9316849 1993-08-13
GB939316849A GB9316849D0 (en) 1993-08-13 1993-08-13 Pharmaceutical compositions
GB9405879 1994-03-24
GB9405879A GB9405879D0 (en) 1994-03-24 1994-03-24 Pharmaceutical compositions

Publications (3)

Publication Number Publication Date
FI943705A0 true FI943705A0 (fi) 1994-08-10
FI943705A FI943705A (fi) 1995-02-14
FI111222B FI111222B (fi) 2003-06-30

Family

ID=26303371

Family Applications (1)

Application Number Title Priority Date Filing Date
FI943705A FI111222B (fi) 1993-08-13 1994-08-10 Menetelmä hybridi-alfa-interferoniliuoksen valmistamiseksi

Country Status (19)

Country Link
US (1) US5609868A (fi)
EP (1) EP0641567B1 (fi)
JP (1) JP3745395B2 (fi)
KR (1) KR100351495B1 (fi)
AT (1) ATE190498T1 (fi)
AU (1) AU679233B2 (fi)
CA (1) CA2129921C (fi)
CY (1) CY2230B1 (fi)
DE (1) DE69423402T2 (fi)
DK (1) DK0641567T3 (fi)
ES (1) ES2144034T3 (fi)
FI (1) FI111222B (fi)
GR (1) GR3033239T3 (fi)
HU (1) HU224613B1 (fi)
IL (1) IL110566A (fi)
NO (1) NO315843B1 (fi)
NZ (1) NZ264218A (fi)
PT (1) PT641567E (fi)
TW (1) TW249202B (fi)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020102236A1 (en) * 1994-12-08 2002-08-01 Taylor Peter William Liposomal interferon hybrid compositions
US20030190307A1 (en) 1996-12-24 2003-10-09 Biogen, Inc. Stable liquid interferon formulations
WO1998028007A1 (en) * 1996-12-24 1998-07-02 Biogen, Inc. Stable liquid interferon formulations
KR19990075253A (ko) * 1998-03-18 1999-10-15 성재갑 약학적으로 안정한 인터페론 제
US6685933B1 (en) * 1998-07-28 2004-02-03 The United States Of America As Represented By The Department Of Health And Human Services Interferon α hybrids
ES2167189B1 (es) * 1999-12-17 2003-04-01 Lipotec Sa Formulacion farmaceutica estable para la administracion intravenosa o intramuscular, de principios activos peptidicos
US6994847B2 (en) 2000-11-07 2006-02-07 Chiron Corporation Stabilized interferon compositions
US6887462B2 (en) * 2001-04-09 2005-05-03 Chiron Corporation HSA-free formulations of interferon-beta
AR044302A1 (es) * 2003-05-13 2005-09-07 Ares Trading Sa Formulaciones con proteinas liquidas estabilizadas en recipientes farmaceuticos
ES2435846T3 (es) * 2005-06-29 2013-12-23 Yeda Research And Development Co. Ltd. Mutantes de Interferón alfa 2 (IFN alfa 2) recombinante

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59196823A (ja) * 1983-04-20 1984-11-08 Sunstar Inc 皮膚および粘膜の真菌症治療用外用剤
US4855238A (en) * 1983-12-16 1989-08-08 Genentech, Inc. Recombinant gamma interferons having enhanced stability and methods therefor
MA20647A1 (fr) * 1985-03-25 1986-10-01 Schering Corp Compositions stables a base d'interferon-gamma
EP0205404B1 (en) * 1985-06-11 1992-07-15 Ciba-Geigy Ag Hybrid interferons
US4847079A (en) * 1985-07-29 1989-07-11 Schering Corporation Biologically stable interferon compositions comprising thimerosal
IL88233A (en) * 1987-11-03 1993-08-18 Genentech Inc Gamma interferon formulation
EP0331635A3 (en) * 1988-02-29 1990-02-28 The Board of Regents of the University of Texas System Preparations for treating bladder cancer

Also Published As

Publication number Publication date
GR3033239T3 (en) 2000-09-29
ES2144034T3 (es) 2000-06-01
NO942983L (no) 1995-02-14
DE69423402D1 (de) 2000-04-20
EP0641567B1 (en) 2000-03-15
CA2129921A1 (en) 1995-02-14
KR950005325A (ko) 1995-03-20
US5609868A (en) 1997-03-11
HU9402356D0 (en) 1994-10-28
CY2230B1 (en) 2003-04-18
AU6893994A (en) 1995-02-23
FI111222B (fi) 2003-06-30
KR100351495B1 (ko) 2003-02-19
FI943705A (fi) 1995-02-14
CA2129921C (en) 2006-12-05
AU679233B2 (en) 1997-06-26
NZ264218A (en) 1995-07-26
ATE190498T1 (de) 2000-04-15
IL110566A0 (en) 1995-01-24
JPH07145070A (ja) 1995-06-06
HUT68692A (en) 1995-07-28
PT641567E (pt) 2000-08-31
IL110566A (en) 1999-12-22
EP0641567A1 (en) 1995-03-08
NO942983D0 (no) 1994-08-12
TW249202B (fi) 1995-06-11
NO315843B1 (no) 2003-11-03
JP3745395B2 (ja) 2006-02-15
DE69423402T2 (de) 2000-08-03
DK0641567T3 (da) 2000-08-14
HU224613B1 (hu) 2005-11-28

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Legal Events

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Owner name: NOVARTIS AG