ES2195309T3 - Derivados de tetrahidrofurano. - Google Patents

Derivados de tetrahidrofurano.

Info

Publication number
ES2195309T3
ES2195309T3 ES98900434T ES98900434T ES2195309T3 ES 2195309 T3 ES2195309 T3 ES 2195309T3 ES 98900434 T ES98900434 T ES 98900434T ES 98900434 T ES98900434 T ES 98900434T ES 2195309 T3 ES2195309 T3 ES 2195309T3
Authority
ES
Spain
Prior art keywords
tetrahydrofuran
derivatives
dihydroxytetrahydro
chem
salt
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES98900434T
Other languages
English (en)
Inventor
Hiroaki Sagawa
Shinji Okuda
Nobuko Muraki
Nobuto Koyama
Katsushige Ikai
Ikunoshin Kato
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takara Bio Inc
Original Assignee
Takara Bio Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takara Bio Inc filed Critical Takara Bio Inc
Application granted granted Critical
Publication of ES2195309T3 publication Critical patent/ES2195309T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/04—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D307/18—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/20—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/04—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D307/18—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/24—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/341—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide not condensed with another ring, e.g. ranitidine, furosemide, bufetolol, muscarine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Abstract

Acido 2,5-dihidroxitetrahidro-2-furancarboxílico representado por la siguiente fórmula [I], su sustancia activa óptimamente o sales de la misma. *fórmula [1]*
ES98900434T 1997-01-27 1998-01-19 Derivados de tetrahidrofurano. Expired - Lifetime ES2195309T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2575597 1997-01-27
JP14606797 1997-05-21

Publications (1)

Publication Number Publication Date
ES2195309T3 true ES2195309T3 (es) 2003-12-01

Family

ID=26363445

Family Applications (1)

Application Number Title Priority Date Filing Date
ES98900434T Expired - Lifetime ES2195309T3 (es) 1997-01-27 1998-01-19 Derivados de tetrahidrofurano.

Country Status (12)

Country Link
US (1) US6133238A (es)
EP (1) EP0994111B1 (es)
KR (1) KR100514071B1 (es)
CN (1) CN1140520C (es)
AT (1) ATE242227T1 (es)
AU (1) AU727225B2 (es)
CA (1) CA2277333A1 (es)
DE (1) DE69815347T2 (es)
EA (1) EA001657B1 (es)
ES (1) ES2195309T3 (es)
TW (1) TW448168B (es)
WO (1) WO1998032749A1 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6492338B1 (en) 1998-06-26 2002-12-10 Takara Shuzo Co., Ltd. Therapeutic agents
CN104119302B (zh) * 2013-07-03 2017-01-18 郑州裕昌有机硅化工有限公司 手性四氢呋喃类化合物及其制备方法和脱水产物

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2727799A1 (de) * 1977-06-21 1979-01-04 Koehler Valentin Verwendung von uronsaeuren, glucarsaeure und deren derivaten fuer die herstellung antimikrobieller mittel
US4950772A (en) * 1988-11-01 1990-08-21 Yamakawa Chemical Industry Co., Ltd. Method of racemization of optically active tetrahydrofuran-2-carboxylic acid
ATE142489T1 (de) * 1990-05-16 1996-09-15 Zbigniew Walaszek Zusammensetzung und verfahren zur prävention und behandlung von hypercholesterinämie und zellproliferationsstorungen

Also Published As

Publication number Publication date
EP0994111B1 (en) 2003-06-04
CA2277333A1 (en) 1998-07-30
EP0994111A1 (en) 2000-04-19
EA199900683A1 (ru) 2000-04-24
AU727225B2 (en) 2000-12-07
EA001657B1 (ru) 2001-06-25
WO1998032749A1 (fr) 1998-07-30
AU5498098A (en) 1998-08-18
CN1244197A (zh) 2000-02-09
DE69815347T2 (de) 2004-04-29
KR20000070476A (ko) 2000-11-25
ATE242227T1 (de) 2003-06-15
CN1140520C (zh) 2004-03-03
KR100514071B1 (ko) 2005-09-09
US6133238A (en) 2000-10-17
DE69815347D1 (de) 2003-07-10
EP0994111A4 (en) 2001-01-24
TW448168B (en) 2001-08-01

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