GR3033239T3 - Stable pharmaceutical compositions containing hybrid alpha-interferon. - Google Patents

Stable pharmaceutical compositions containing hybrid alpha-interferon.

Info

Publication number
GR3033239T3
GR3033239T3 GR20000400921T GR20000400921T GR3033239T3 GR 3033239 T3 GR3033239 T3 GR 3033239T3 GR 20000400921 T GR20000400921 T GR 20000400921T GR 20000400921 T GR20000400921 T GR 20000400921T GR 3033239 T3 GR3033239 T3 GR 3033239T3
Authority
GR
Greece
Prior art keywords
interferon
pharmaceutical compositions
compositions containing
hybrid alpha
stable pharmaceutical
Prior art date
Application number
GR20000400921T
Other languages
English (en)
Inventor
Nicholas Lowther
John Douglas Allen
Colin Howes
Original Assignee
Novartis Erfind Verwalt Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB939316849A external-priority patent/GB9316849D0/en
Priority claimed from GB9405879A external-priority patent/GB9405879D0/en
Application filed by Novartis Erfind Verwalt Gmbh filed Critical Novartis Erfind Verwalt Gmbh
Publication of GR3033239T3 publication Critical patent/GR3033239T3/el

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • A61K38/21Interferons [IFN]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12Carboxylic acids; Salts or anhydrides thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • A61K38/21Interferons [IFN]
    • A61K38/212IFN-alpha
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183Amino acids, e.g. glycine, EDTA or aspartame
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Dermatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
GR20000400921T 1993-08-13 2000-04-14 Stable pharmaceutical compositions containing hybrid alpha-interferon. GR3033239T3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB939316849A GB9316849D0 (en) 1993-08-13 1993-08-13 Pharmaceutical compositions
GB9405879A GB9405879D0 (en) 1994-03-24 1994-03-24 Pharmaceutical compositions

Publications (1)

Publication Number Publication Date
GR3033239T3 true GR3033239T3 (en) 2000-09-29

Family

ID=26303371

Family Applications (1)

Application Number Title Priority Date Filing Date
GR20000400921T GR3033239T3 (en) 1993-08-13 2000-04-14 Stable pharmaceutical compositions containing hybrid alpha-interferon.

Country Status (19)

Country Link
US (1) US5609868A (el)
EP (1) EP0641567B1 (el)
JP (1) JP3745395B2 (el)
KR (1) KR100351495B1 (el)
AT (1) ATE190498T1 (el)
AU (1) AU679233B2 (el)
CA (1) CA2129921C (el)
CY (1) CY2230B1 (el)
DE (1) DE69423402T2 (el)
DK (1) DK0641567T3 (el)
ES (1) ES2144034T3 (el)
FI (1) FI111222B (el)
GR (1) GR3033239T3 (el)
HU (1) HU224613B1 (el)
IL (1) IL110566A (el)
NO (1) NO315843B1 (el)
NZ (1) NZ264218A (el)
PT (1) PT641567E (el)
TW (1) TW249202B (el)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020102236A1 (en) * 1994-12-08 2002-08-01 Taylor Peter William Liposomal interferon hybrid compositions
US20030190307A1 (en) * 1996-12-24 2003-10-09 Biogen, Inc. Stable liquid interferon formulations
EE04223B1 (et) * 1996-12-24 2004-02-16 Biogen, Incorporated Interferooni stabiilne vedelkompositsioon, mis sisaldab aminohappeid
KR19990075253A (ko) * 1998-03-18 1999-10-15 성재갑 약학적으로 안정한 인터페론 제
US6685933B1 (en) 1998-07-28 2004-02-03 The United States Of America As Represented By The Department Of Health And Human Services Interferon α hybrids
ES2167189B1 (es) * 1999-12-17 2003-04-01 Lipotec Sa Formulacion farmaceutica estable para la administracion intravenosa o intramuscular, de principios activos peptidicos
IL155788A0 (en) 2000-11-07 2003-12-23 Chiron Corp Stabilized interferon compositions
US6887462B2 (en) * 2001-04-09 2005-05-03 Chiron Corporation HSA-free formulations of interferon-beta
AR044302A1 (es) * 2003-05-13 2005-09-07 Ares Trading Sa Formulaciones con proteinas liquidas estabilizadas en recipientes farmaceuticos
BRPI0613098A2 (pt) * 2005-06-29 2010-12-21 Yeda Res & Dev mutantes de interferon a2 (ifna2) recombinantes

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59196823A (ja) * 1983-04-20 1984-11-08 Sunstar Inc 皮膚および粘膜の真菌症治療用外用剤
US4855238A (en) * 1983-12-16 1989-08-08 Genentech, Inc. Recombinant gamma interferons having enhanced stability and methods therefor
EP0196203A3 (en) * 1985-03-25 1987-09-30 Schering Corporation Stable gamma interferon formulation
EP0205404B1 (en) * 1985-06-11 1992-07-15 Ciba-Geigy Ag Hybrid interferons
US4847079A (en) * 1985-07-29 1989-07-11 Schering Corporation Biologically stable interferon compositions comprising thimerosal
IL88233A (en) * 1987-11-03 1993-08-18 Genentech Inc Gamma interferon formulation
EP0331635A3 (en) * 1988-02-29 1990-02-28 The Board of Regents of the University of Texas System Preparations for treating bladder cancer

Also Published As

Publication number Publication date
CA2129921C (en) 2006-12-05
HUT68692A (en) 1995-07-28
KR100351495B1 (ko) 2003-02-19
HU9402356D0 (en) 1994-10-28
AU679233B2 (en) 1997-06-26
ES2144034T3 (es) 2000-06-01
HU224613B1 (hu) 2005-11-28
EP0641567B1 (en) 2000-03-15
FI943705A0 (fi) 1994-08-10
EP0641567A1 (en) 1995-03-08
CA2129921A1 (en) 1995-02-14
PT641567E (pt) 2000-08-31
JP3745395B2 (ja) 2006-02-15
FI943705A (fi) 1995-02-14
AU6893994A (en) 1995-02-23
NO942983L (no) 1995-02-14
DE69423402D1 (de) 2000-04-20
JPH07145070A (ja) 1995-06-06
US5609868A (en) 1997-03-11
NO942983D0 (no) 1994-08-12
DE69423402T2 (de) 2000-08-03
IL110566A (en) 1999-12-22
TW249202B (el) 1995-06-11
IL110566A0 (en) 1995-01-24
NO315843B1 (no) 2003-11-03
ATE190498T1 (de) 2000-04-15
KR950005325A (ko) 1995-03-20
FI111222B (fi) 2003-06-30
CY2230B1 (en) 2003-04-18
DK0641567T3 (da) 2000-08-14
NZ264218A (en) 1995-07-26

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Legal Events

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