FI943024A0 - Proteiner inhiberande stamceller - Google Patents

Proteiner inhiberande stamceller

Info

Publication number
FI943024A0
FI943024A0 FI943024A FI943024A FI943024A0 FI 943024 A0 FI943024 A0 FI 943024A0 FI 943024 A FI943024 A FI 943024A FI 943024 A FI943024 A FI 943024A FI 943024 A0 FI943024 A0 FI 943024A0
Authority
FI
Finland
Prior art keywords
stem cells
inhibiting stem
proteins inhibiting
proteins
cells
Prior art date
Application number
FI943024A
Other languages
English (en)
Finnish (fi)
Other versions
FI943024A (sv
Inventor
Stewart Craig
Michael George Hunter
Richard Mark Edwards
Lloyd George Czaplewski
Richard James Gilbert
Original Assignee
British Bio Technology
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB919127319A external-priority patent/GB9127319D0/en
Priority claimed from GB929221587A external-priority patent/GB9221587D0/en
Application filed by British Bio Technology filed Critical British Bio Technology
Publication of FI943024A0 publication Critical patent/FI943024A0/sv
Publication of FI943024A publication Critical patent/FI943024A/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/521—Chemokines
    • C07K14/523—Beta-chemokines, e.g. RANTES, I-309/TCA-3, MIP-1alpha, MIP-1beta/ACT-2/LD78/SCIF, MCP-1/MCAF, MCP-2, MCP-3, LDCF-1, LDCF-2
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/67—General methods for enhancing the expression
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • C12N15/815—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts for yeasts other than Saccharomyces
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
FI943024A 1991-12-23 1994-06-22 Proteiner inhiberande stamceller FI943024A (sv)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB919127319A GB9127319D0 (en) 1991-12-23 1991-12-23 Modified proteins
GB929221587A GB9221587D0 (en) 1992-10-14 1992-10-14 Modified proteins
PCT/GB1992/002390 WO1993013206A1 (en) 1991-12-23 1992-12-23 Stem cell inhibiting proteins

Publications (2)

Publication Number Publication Date
FI943024A0 true FI943024A0 (sv) 1994-06-22
FI943024A FI943024A (sv) 1994-06-22

Family

ID=26300071

Family Applications (1)

Application Number Title Priority Date Filing Date
FI943024A FI943024A (sv) 1991-12-23 1994-06-22 Proteiner inhiberande stamceller

Country Status (10)

Country Link
US (2) US6057123A (sv)
EP (1) EP0627003A1 (sv)
JP (1) JPH07502404A (sv)
AU (1) AU679436B2 (sv)
CA (1) CA2125985C (sv)
FI (1) FI943024A (sv)
HU (2) HUT69788A (sv)
NO (1) NO942380L (sv)
NZ (1) NZ246354A (sv)
WO (1) WO1993013206A1 (sv)

Families Citing this family (50)

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GB9308060D0 (en) * 1993-04-19 1993-06-02 Cancer Res Campaign Tech Stem cell inhibitor
GB9312344D0 (en) * 1993-06-15 1993-07-28 British Bio Technology Pharmaceutical formulations
US5728377A (en) * 1993-07-20 1998-03-17 Board Of Regents, The University Of Texas System Methods and compositions incorporating IP-10
CA2179638A1 (en) * 1993-12-24 1995-07-06 Peter Schulz-Knappe Human circulating cytokine cc-1
GB9517014D0 (en) * 1995-08-19 1995-10-25 British Biotech Pharm Haematopoietic recovery
US5786335A (en) * 1995-11-06 1998-07-28 Warner-Lambert Company Sulfhydryl containing peptides for treating vascular disease
GB9600559D0 (en) * 1996-01-11 1996-03-13 British Biotech Pharm Use of chemokines
AU4561497A (en) * 1996-09-25 1998-04-17 British Biotech Pharmaceuticals Limited Human rantes mutants incapable of aggregate formation
US6121023A (en) * 1998-01-22 2000-09-19 Akzo Nobel N.V. Isothermal transcription based assay for the detection and quantification of the chemokine rantes
CA2245224A1 (en) 1998-08-14 2000-02-14 Jiang-Hong Giong Chemokine receptor antagonists and chemotherapeutics
JP2002506830A (ja) 1998-03-13 2002-03-05 ザ ユニバーシティ オブ ブリティッシュ コロンビア 治療的ケモカイン受容体アンタゴニスト
CA2305787A1 (en) 2000-05-09 2001-11-09 The University Of British Columbia Cxcr4 antagonist treatment of hematopoietic cells
US7378098B2 (en) 2000-04-12 2008-05-27 The University Of British Columbia CXC chemokine receptor 4 agonist peptides
US7368425B2 (en) 2006-03-24 2008-05-06 Chemokine Therapeutics Corp. Cyclic peptides for modulating growth of neo-vessels and their use in therapeutic angiogenesis
CA2335109A1 (en) * 2000-04-12 2001-10-12 Chemokine Therapeutics Corporation Cxcr4 agonist treatment of hematopoietic cells
US20050059584A1 (en) 2002-08-16 2005-03-17 Ahmed Merzouk Novel chemokine mimetics synthesis and their use
US7311905B2 (en) 2002-02-13 2007-12-25 Anthrogenesis Corporation Embryonic-like stem cells derived from post-partum mammalian placenta, and uses and methods of treatment using said cells
JP4294316B2 (ja) 2000-12-06 2009-07-08 ハリリ，ロバート，ジェイ． 胎盤幹細胞の回収方法
EP2316918B1 (en) 2001-02-14 2015-07-01 Anthrogenesis Corporation Post-partum mammalian placenta, its use and placental stem cells therefrom
US6515001B2 (en) 2001-03-05 2003-02-04 Chemokine Therapeutic Corporation IL-8 receptor ligands-drugs for inflammatory and autoimmune diseases
ATE421974T1 (de) * 2001-12-17 2009-02-15 Serono Lab Chemokine mutanten, die als chemokine antagonisten wirken
US7682803B2 (en) 2005-10-13 2010-03-23 Anthrogenesis Corporation Immunomodulation using placental stem cells
US7498171B2 (en) * 2002-04-12 2009-03-03 Anthrogenesis Corporation Modulation of stem and progenitor cell differentiation, assays, and uses thereof
CN1668733A (zh) * 2002-05-30 2005-09-14 细胞基因公司 利用jnk或mkk抑制剂调节细胞分化并治疗骨髓增生异常和脊髓发育不良综合症的方法
JP2004196770A (ja) * 2002-10-24 2004-07-15 Effector Cell Institute Inc 樹状細胞前駆体の血中レベル上昇剤
BR0316695A (pt) 2002-11-26 2005-10-18 Anthrogenesis Corp Unidade citoterapêutica, kit para tratamento, método de tratamento de uma enfermidade, biblioteca de unidades citoterapêuticas e método de tratamento de um paciente
AU2005326226B2 (en) * 2005-01-31 2010-11-11 Eci, Inc. Immunopotentiating agent
ES2706726T3 (es) 2005-12-29 2019-04-01 Celularity Inc Poblaciones de células madre placentarias
WO2007079184A2 (en) 2005-12-29 2007-07-12 Anthrogenesis Corporation Co-culture of placental stem cells and stem cells from a second source
US7993918B2 (en) * 2006-08-04 2011-08-09 Anthrogenesis Corporation Tumor suppression using placental stem cells
JP5979811B2 (ja) 2007-02-12 2016-08-31 アンスロジェネシス コーポレーション 胎盤幹細胞を使用した炎症性疾患の治療
TWM322542U (en) * 2007-05-23 2007-11-21 Universal Scient Ind Co Ltd Testing machine
US9200253B1 (en) 2007-08-06 2015-12-01 Anthrogenesis Corporation Method of producing erythrocytes
EP2203176B1 (en) 2007-09-28 2014-11-26 Anthrogenesis Corporation Tumor suppression using human placental perfusate and human placenta-derived intermediate natural killer cells
PE20110399A1 (es) * 2008-08-20 2011-06-22 Anthrogenesis Corp Tratamiento de la apoplejia utilizando celulas placentarias aisladas
WO2010021714A2 (en) 2008-08-20 2010-02-25 Anthrogenesis Corporation Improved cell composition and methods of making the same
JP2012500792A (ja) 2008-08-22 2012-01-12 アンスロジェネシス コーポレーション 胎盤細胞集団による骨欠損の治療のための方法および組成物
KR20110086176A (ko) 2008-11-19 2011-07-27 안트로제네시스 코포레이션 양막 유래 부착성 세포
MX353489B (es) * 2009-07-02 2018-01-16 Anthrogenesis Corp Metodo para producir eritrocitos sin celulas alimentadoras.
EP2529007B1 (en) 2010-01-26 2017-07-12 Anthrogenesis Corporation Treatment of bone-related cancers using placental stem cells
MX347451B (es) 2010-04-07 2017-04-27 Anthrogenesis Corp Angiogenesis utilizando celulas madre placentarias.
JP2013523823A (ja) 2010-04-08 2013-06-17 アントフロゲネシス コーポレーション 胎盤幹細胞を用いるサルコイドーシスの治療
KR20180099915A (ko) 2010-07-13 2018-09-05 안트로제네시스 코포레이션 천연 킬러 세포의 생성 방법
AR093183A1 (es) 2010-12-31 2015-05-27 Anthrogenesis Corp Aumento de la potencia de celulas madre de placenta usando moleculas de arn moduladoras
DK2714059T3 (en) 2011-06-01 2019-01-21 Celularity Inc TREATMENT OF PAIN WHEN USING PLACENT STAM CELLS
US9925221B2 (en) 2011-09-09 2018-03-27 Celularity, Inc. Treatment of amyotrophic lateral sclerosis using placental stem cells
CN115137753A (zh) 2013-02-05 2022-10-04 细胞结构公司 来自胎盘的自然杀伤细胞
KR102682118B1 (ko) * 2016-04-29 2024-07-08 주식회사유한양행 Ccl3 변이체를 포함하는 융합 단백질 및 이의 용도
WO2020014298A1 (en) 2018-07-10 2020-01-16 Rush University Medical Center Use of immunomodulators to control infection and stimulate healing in normal and diabetic wounds
WO2024092025A1 (en) 2022-10-25 2024-05-02 Nykode Therapeutics ASA Constructs and their use

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4929555A (en) * 1987-10-19 1990-05-29 Phillips Petroleum Company Pichia transformation
DE69020573T3 (de) * 1989-09-25 1999-12-16 Crc Technology Ltd., London Verfahren zur wachstumshemmung von stammzellen.
JPH03228683A (ja) * 1989-12-20 1991-10-09 Chemo Sero Therapeut Res Inst 生理活性ペプチドＬＤ７８α、ＬＤ７８βおよびその製法、これに用いる組換えプラスミド
JPH06503710A (ja) * 1990-09-14 1994-04-28 カイロン　コーポレイション 酵母細胞におけるマクロファージ誘導タンパク質（ｍｉｐ）の発現

Also Published As

Publication number Publication date
EP0627003A1 (en) 1994-12-07
HU9401902D0 (en) 1994-09-28
AU679436B2 (en) 1997-07-03
NZ246354A (en) 1995-10-26
HUT69788A (en) 1995-09-28
NO942380D0 (sv) 1994-06-22
WO1993013206A1 (en) 1993-07-08
JPH07502404A (ja) 1995-03-16
US5856301A (en) 1999-01-05
FI943024A (sv) 1994-06-22
CA2125985A1 (en) 1993-07-08
CA2125985C (en) 2001-04-17
HU211605A9 (en) 1995-12-28
US6057123A (en) 2000-05-02
AU3260493A (en) 1993-07-28
NO942380L (no) 1994-08-23

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Owner name: BRITISH BIOTECH PHARMACEUTICALS LIMITED